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Rickettsia Part 2
Microbiology 1 - Rickettsia Part 2
Question | Answer |
---|---|
Typhus Fever | Rickettsia Prowazeki |
Typhus Fever History | WWI - 3 million died |
Louse bites | lice deposit organism next to bite, person scratches = transmission |
lice abandon | dead bodies & those w/high fevers |
typhus fever incubation | 12 days |
Rash development | trunk then to extremities |
typhus fever treatement | antibiotic therapy (erythromycin / chloramphenicol) |
typhus fever mortality | 3-40% |
Brill's Zinsser | Rickettsia Prowazeki reactivation |
Brill's Zinsser aka | recrudescent fever typhus |
Brill's Zinsser studied among | NYC European immigrants |
Brill's Zinsser has | milder symptoms & short duration |
Brill's Zinsser often no | skin rash |
Brill's Zinsser caused by | reactiviation of organism that has been in lymph nodes |
Brill's Zinsser serologically distinguished | from epidemic typhus |
Endemic/Murine Typhus | Rickettsia Typhi |
R. Typhi | rat associated, transmission similar to plague |
R. Typhi transmission | by scratch - organism enters mucous membranes |
R. Typhi incubation | 10-14 days |
R. Typhi Sx: | high fever, headache, rash |
R. Typhi | self-limiting - 2 wks if untreated |
R. Typhi mortality | 2% |
Scrub Typhus | Rickettsia Tsutsugamushi |
R. Tsutsugamushi | Japanese for "bad little bug" |
R. Tsutsugamushi | when soldiers crawled on bellies |
R. Tsutsugamushi Sx: | fever, chills, headache - sloughing lesion at site of bite = spotty rash |
R. Tsutsugamushi moratily if untreated | 50% |
Rickettsial Pox | Rickettsi Akari |
Rickettsi Akari | resembles chicken pox |
Rickettsi Akari | not deadly |