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urinary
anatomy
extracellular fluid | consists of blood plasma, interstitial fluid, transcellular fluid (CSF, joint fluids, eye humors), lymph; provides constant environment for cells and transporting substances |
intracellular fluid | water inside the cells; facilitates intracellular chemical reactions |
aldosterone | helps restore normal ECF; decreased blood pressure or increased K+ levels |
angiotensin I & II | increase aldosterone secretion |
factors that determine urine volume | glomerular filtration rate & rate of water reabsorption by kidney tubules |
urine volume | regulated by secretion of ADH or ANH (ADH reduces water loss; ANH prevents loss of Na+ via urine) |
urinary system | main organ is the kidneys; excretes nitrogen compounds, toxins, water, electrolytes |
hilum | concave notch on the medial surface of the kidneys; site of entry and exit of blood vessels and other structures |
renal cortex | outer region |
renal medulla | inner region |
renal pyramids | triangular wedges that make up much of the medullary tissue |
renal columns | areas where cortical tissue dips between pyramids |
calyx | cuplike structures; site of urine collection that is ready to leave the body |
renal artery | large branch of the abdominal aorta brings blood into each kidney; divides into segmental then lobar arteries |
afferent arterioles | carry blood directly to nephrons |
ureters | convey urine from kidneys to bladder; lined with urothelium |
urinary bladder | urine reservoir; expels urine from the body through the urethra |
detrusor muscle | bundles of smooth muscle that makes up the wall of the bladder |
micturition | urination; voiding; increased pressure against bladder wall stimulates involuntary micturition contractions; causes internal urethral sphincter muscles to relax |
external urethral sphincter | voluntary contractions |
nephrons | makes up the bulk of each kidney; renal corpuscle and renal tubule |
renal corpuscle | glomerular capsule and glomerulus; fluid filters out of the glomerulus and into the gl. capsule |
glomerular capsule | Bowman capsule; filtrate enters this space to be processed in the nephron |
glomerulus | network of capillaries |
renal tubule | extends from renal corpuscle to the end of the nephron where it joins a collecting dust; divided into the proximal convoluted tubule, nephron loop, and distal convoluted tubule |
proximal convoluted tubule | second part of nephron but first part of renal tubule; wall consists of epithelial cells that have a brush border with microvilli, increasing its surface area |
nephron loop | Henle loop; descending and ascending limb; its length is important in production of highly concentrated or dilute urine |
distal convoluted tubule | conducts filtrate out of a nephron and into a collecting duct |
juxtaglomerular apparatus | secretes renin when blood pressure in afferent arteriole drops; contribute to homeostasis by controlling the ability to produce concentrated urine from the kidneys |
collecting duct | formed by joining of renal tubules of several nephrons; release urine into a minor calyx |
kidney | process blood plasma and excretes urine; sodium, chloride, nitrogen (urea), potassium; forms urine by filtration, reabsorption, and secretion |
urine | ~95% water; pH 4.6-8.0 |
filtration | first step; occurs in renal corpuscles |
reabsorption | occurs as a result of passive and active transport mechanisms from the renal tubules; major portion occurs in PCTs |
regulation of urine volume | ADH influences water reabsorption, reduces water loss; aldosterone increases sodium reabsorption and promotes water reabsorption; ANH promotes loss of Na+, produces more urine |