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Bacteriophage
Microbiology - comparison of bacteriophage & animal virus
Stage | Bacteriophage | Animal Virus |
---|---|---|
Attachment sites | attachment of tail fibers to cell wall proteins | attachment of spikes, capsid, or envelope to plasm a membrane proteins |
Penetration | injection of viral nucleic acid through bacterial cell wall | endocytosis or fusion |
uncoating | none needed | enzymatic digestion of viral proteins |
synthesis | in cytoplasm; bacterial synthesis ceased; Viral DNA or RNA replicated, formation of viral mRNA; viral components synthesized | host cell synthesis ceased; Viral DNA or RNA replictaed, formation of viral RNA; Viral components synthesized |
maturation | addition of collar, sheath, base plate, & tail fibers to viral nucleic acid-containing head | insertion of viral nucleic acid into capsid |
release | host cell lysis | budding (enveloped viruses), cell rupture (nonenvelopedviruses) |
Chronic infection | lysogeny | latency, chronic infection, cancer |