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Properties of Toxins
Microbiology - Properties of Toxins
side one | side two |
---|---|
mostly Gram+, some Gram- | exotoxins |
extracellular, excreted into medium | exotoxins |
unstable, denatured above 60 degrees & ultraviolet light | exotoxins |
most powerful toxins | exotoxins |
highly specific, some act as neurotoxins or cardiac m. toxins | exotoxins |
little or no fever produced | exotoxins |
strong antigenicity; stimulates antibody production & immunity | exotoxins |
treatment with heat or chemicals; toxoid used to immunize against toxins | exotoxins |
Ex: botulism, gas gangrene, tetanus, diptheria, staphylococcal food poisoning, cholera, entertoxins, plague | exotoxins |
mostly Gram+ | endotoxins |
bound withing bacterial cell wall; released upon death of bacterium | endotoxins |
lipopolysaccharide complex | endotoxins |
relatively stable; can withstand several hours above 60 degrees | endotoxins |
weak, but can be fatal in relatively large doses | endotoxins |
nonspecific; ache all over systemic effects or local site reactions | endotoxins |
rapid rise in temperature to high fever | endotoxins |
weak; recovery from disease often does not produce immunity | endotoxins |
cannot be converted to toxoid; cannot be used to immunize | endotoxins |
Ex: Salmonellosis, tularemia, endotoxic shock | endotoxins |