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Session 2 CM pulm2
CM- pulm -2- Asthma 1&2
Question | Answer |
---|---|
What is the pathogenesis of Asthma | chronic inflammatory disease IgE combines with antigen triggering histamine release causing leaky venules, increased airway secretion stimulates irritant receptors and vagal release of ACH causing BRONCHOconstriction |
What are the assoicated s/sx of asthma | coughing, wheezing, breathlessness and chest tightness. |
Are the s/sx of asthma reversible | usually reversible |
What innate immunity response can cause ashtma | TH1 and TH2 type cytokine responses |
What environmental factors can cause asthma | airborne allergens, viral respiratory infections |
what is the triad of asthma | Dyspnea, Cough, Wheezing |
When are asthma symptoms worse | worse at night or early morning |
When running spirometry what will you administer to check for asthma | give a bronchodilator looking for 12% improvement pre vs post bronchodilator |
What are the biomarkers for inflammation in asthma | eosinophils and sputum |
What are the treatment goals with asthma | reduce impairment reduce risk- prevent exacerbations |
what are the four components of asthma care | 1 asses severity and control of asthma 2 EDUCATION 3 control environmental factors and comorbid conditions 4 Medications |
When thinking of impairment from asthma what should come to mind | current problems such as night time awakenings, activity limitations |
When thinking of risks and asthma what should come to mind | think of risks as future problems controlling future frequency and exacerbation of asthma or occurence of tx related adverse effects |
Does increased impairment from asthma equate to an increase in asthma risk | no |
Assess severity to _______ Therapy and Assess control to ________ therapy | Assess severity to initiate Therapy and Assess control to adjust therapy |
in component 2 of asthma treatment, education, what do you want to accomplish | ensure the family and patient understand basic facts about asthma, role of medication long term and short term acting medicines and controlling environmental conditions like possibly getting rid of a pet or smoking or other habits |
What comorbid conditions can exacerbate asthma | GERD, Obesity, OSA, rhinnitis/sinusitis, stress/depression |
What are the long term medications for treating asthma | corticosteroids, mast cell stablilizers, immunomodulators, leukotriene modifiers, LABA salmetrol and formoterol, methylxanthines |
What are the short acting meds for asthma tx | anticholinergics SABAs- albuterol, levalbuterol pirbuterol systemic corticosteroids |
after giving a tx for asthma what should you do | follow up and evaluate the controls see if you need to step up treatment or if you can step down tx |
If you aren't getting the desired control of the asthmas what should you look at | review pt's compliance if compliance is ok step up medications consider alternative diagnosis |
what would be considered mild asthma | dyspnea only with activity |
what would be considered moderate asthma | dyspnea interferes or limits usual activity |
What would be considered severe asthma | dyspnea at rest or interferes with conversation |
what would be considered life threatening asthma | too dyspneic to speak or perspiring |