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CNS - Cerebellum

CNS 2nd lecture exam - Cerebellum

Cerebellum intergrate very rapidly information on what ? (3) 1. Momentary status of muscle contraction 2. Joint tension 3. Visual and auditory input on equilibrium
Cerebellum makes our movements ___? Smooth and effective (influences muscle tone and posture)
Right cerebellar hemisphere deals with which side of the body? Right
___ is one of the cerebellum's greates attributes? Compensation
The cerebellum is attache to the MO via the ___. To the pons via the ___ and the midbrain via the ____ 1. Inferior cerebellar peduncle - restiform body 2. Middle cerebellar peduncle 3. Superior cerebellar peduncle
Most common brain tumor in a child is a ___? Where does it occur? 1. Medulloblastoma 2. Superior medullary velum
External subdivisions of the cerbellum? Median = vermis Lateral = Hemispheres
Inferior cerebellar peduncle: __ dominate and __ are present Afferent dominate and efferent are present
Middle cerebellar peduncle: ___ fibers only! Afferent
Superior cerebellar peduncle: __ dominate and ___ are present Efferent fibers dominate and afferent fibers are present
What is the white mater of the cerebellum called? Corpus meduallare
White matter of cerebellum is continuous with what? The 6 cerebellar peduncles
Extension of white matter toward the periphery appear as a branching tree called the what? Arbor Vitae
The anterior of Paleocerebellar lobe receives its input from which 2 tracts? Spinocerebellar and cuneocerebellar
The function of the paleocerebellar lobe? General muscle tone
The posterior or neocerebellar layer gets its input from where and what is its function? 1.Corticopontocerebellar 2. Coordination of skilled movement
The flocculonodular lobe receives input from where and its function? 1. Vestibular nucleus 2. Equilibrium
Isolated in the white matter are 4 pairs of nuclei called the what? Central cerebellar nuclei
Types of neurons in the cerebellum? Perkinje, golgi II, Stellate, Basket, Grannular
Two axons that bring input to the cerebellum? Mossy and climbing fibers
How might the cerebellum deal with restoring muscle tone of the left thigh? 1. Anterior spinocerebellar tract will take input to the inferior and-or superior cerebellar peduncles. 2. From there, fibers will travel to the anterior lobe. 3. From there, fibers will go down to the globose and fastigial nucleus.
What fibers take messages away from the cerebellum? (efferent) Purkinje fibers
Most purkinje axons terminate in the ___. But a few bypass to ___. What neurotransmitter do they release? 1. Deep central cerebellar nuclei 2. Deiter's portion of the vestibular nuclei 3. GABA
Grannular cells are stimulates by incomming what? Mossy fibers
Grannular cells are stimulated by what? Glutamate
Mossy fibers originate where? Spinocerebellar and corticopontocerebellar tracts
Information leaves the cerebellar cortex via ___? Their inhibitory target is the what? 1. Perkinje cells 2. Deep cerebellar nuclei
Grannular cells are excitatory to what? Neurotransmitter? 1. Perkinje cells 2. Glutamate
Where do climbing fibers originate? Neurotransmitter? 1. Inferior olivary nucleus 2. Aspartate
Purkinje cell layer is composed of haw many cell bodies? 30 million
Are pukinje cells excititory or inhibitory? Inhibitory
What is the most abundant neurotransmitter in the brain? Glutamate!
How many grannular cells are there? 3-7 million per mm3
Mossy fibers stimulate what? Excitory or inhibitory? 1. Grannular cells 2. Excititory
Which are more numorus: mossy or climbing fibers? Mossy
Grannular cells synapse with what? They are ___ and release what? 1. Purkinje 2. Excititory 3. Glutamate
Purkinje are stimulated by 2 excititory cells? Mossy and climbing fibers
Input from climbing and mossy fibers is intergrates through which cells? Perkinje, stelate, basket, golgi II, grannular
Mossy fibers are excitatory to what? Grannular cells
Purkinje cells go where? Excitatory or inhibitory? Neurotransmitter? 1. Deep nuclei 2. Inhibitory 3. GABA
Climbing fibers go where? Excitatory or inhibitory? Neurotransmitter? 1. Purkinje cells 2. Extremly excitatory 3. Aspartate
Largest and most lateral nuclei? Dentate
The anterior lobe of cerebellum synapses with which 2 deep nuclei? Globose and fastigial
The posterior lobe synapses with what deep nuclei? Eboliform and dentate
What does the flocculonodual lobe synapse with? Fastigial nuclei
Efferent cerebella outflow: Where does the fastigial nucleus terminate? Via what? Vestibular nuclei and CN 3, 4 and 6 via the inferiror cebrebellar peduncle
Cerebellar outflow: where do globose axons terminate? Via what? Red nucleus and reticular formation via the superior cerebellar peduncle
Cerebellar efferent outflow: Where do the dentate and eboliform axons terminate? Red nucleus and thalamus via the superior cerebellar peduncle
Is the cerebellar functionally ipsi or bilateral? Ipsilateral
Equilibrium disturbances where patient fights from falling backwards AKA what? This is due to a lesion in this lobe. Flocculonodular syndrome due to a lesion in the flocculonodular lobe
Ataxia is what and results from a lesion in what lobe? Lack of order of coordination due to a lesion in the neocerebellum
Intension tremors are common in what lobe? Neocerebellar
What is dysmetria? When you over or undershoot your target
Repetative jerking movements of the eyeballs is called what? This is due to a ___ impairement. 1. Nystagmus 2. Flocculus-Fastigial impairment
Nystagmus is related to which cranial nerves? 3,4,6
Created by: LrB