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Path 1 Exam 2 Renal
Dr. Kashif
Question | Answer |
---|---|
Simplest filtration unit | nephron |
Kidneys function | Formation of urine, Vit D activation, formation erythropoietin, regulate BP |
What is filtered in the kidneys | blood |
4 processes that take place in kidneys | filtration, reabsorption, secretion (toxic back into urine), excretion |
What is not being filtered in the blood | Proteins, too large and negatively charged |
Normal urine protein range is how much mgm per 24 hrs | 100-150 mgm |
what is the test for protein in urine | Urine D/R |
Urine culture (CS) evaluates | presence of bateria in urine |
IF GFR is decreased this is called | Prerenal Azotemia |
IF urine flow is obstructed | postrenal Azotemia |
Two type of syndromes that result in glomerular disease | Nephritic syndrome vs Nephrotic syndrome |
Nephritic vs Nephrotic, primary defect is decreased GFR | Nephritic |
Nephrotic syndromes Primary defect is increased permeability of__________ | Glomerular to filter protein |
Define oliguria | less output than input (not enough urine) |
Nephritic vs Nephrotic results in Oliguria | Nephritic |
Nephritic vs Nephrotic results in proteinuria | Nephrotic |
Nephritic vs Nephrotic, ass. w/ hematuria | Nephritic |
Nephritic vs Nephrotic Proteinuria less than 3.5grams/day | Nephritic |
Nephritic vs Nephrotic Increase blood urea nitrogen (BUN) and creatinine | Nephritic |
Define hypoproteinemia | Decreased plasma proteins in blood (albumin) loss of protein in urine |
Why do we loose water in the blood in hypoproteinemia | Proteins are lose and they exert osmotic pressure resulting in edema of face and feet, water out of cell into interstitial |
Nephritic vs Nephrotic Hypoproteinemia | Nephortic |
Nephritic vs Nephrotic Proteinuria (loosing proteins) >3.5grams | Nephrotic |
Nephritic vs Nephrotic Hypertension | Nephritic |
associated with inflammation in glomeruli | nephritic |
Nephritic vs Nephrotic edema may or may not be present | Nephritic |
Nephritic vs Nephrotic always ass. w/ EDEMA | |
Proteins retain _______ in the blood | water |
Nephritic vs Nephrotic HyperLipidemia | Nephrotic (increase lipoproteins) |
Nephritic vs Nephrotic Lipiduria | lipoproteins in urine |
Nephritic vs Nephrotic RBS in urine | nephritic |
If kidney diseases are not taken care of they will result in | Renal Failure |
ESRD stands for | End Stage Renal Disease |
The degree of renal failure can be measured by determining _____ | GFR, =125ml/minute |
When GFR is decreased from 125ml/minute to 10-20ml patient requires use of | Renal dialysis |
T or F Renal failure always developes quickly | False, can develop acutely or slowly over many years |
T or F, high dose of Vit C can cause kidney stones | TRUE |
2 chemical markers in blood that are increased in Renal Failure | Creatinine, BUN |
ESRD or ESRF is ass. w/ dialysis | ESRF |
3 conditions ass. w/ Nephritis syndrome | 1st Acute Prolif PostStrep Gnephritis, 2nd IgA nephropathy, 3rd Rapidly progressive Gnephritis |
What syndrome first occurs 1-4 wks after a streptococcal infection | Acute Proliferative poststreptococcal GlomerulonephRITIS…. Ass/ w/ red-brown urine |
Acute Proliferative poststreptococcal GlomerulonephRITIS cases occur in what age group | 6-10 years old |
Berger disease is a | IgA nephropathy ("immune response") |
in APpSGnephritis do most patients recover? | yes most cases do, some progress to crescentic Gnephritis |
Berger disease age group | children and young adults |
Mesangial deposition of IgA in children is which disease | Berger disease |
Henoch Schnolein is another name for | Berger disease/IgA nephropathy |
T or F 50% of cases of IgA nephropathy lead to renal failure | True |
Which disease is ass. w/ recurrent microscopic and gross hematuria | berger disease |
Crescents composed of cells and protein in the glomerulus is ass. w/ | RPGN Rapidly progressive (crecentic) GlomeruloNephritis |
What 3 Typediseases can lead to RPGN | |
Nephritic syndromes can lead to _ _ _ _ if not treated succesfully | ESRD |