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pharmacology drugs
| Name | Receptor | Used in |
|---|---|---|
| Acetylcholine (ACh) | muscarinic and nicotinic agonist. | neurotransmitter |
| Adrenaline | non-selective adrenoreceptor agonist. | cardiac arrest anaphylaxis (allergic rxn) |
| Atropine | non-selective muscarinic agonist | premedication before surgery bardycardia (low BPM) GI spasms anticholinesterase poisoning |
| Bethanecol | non-selective muscarinic agonist | urinary retension constipation -relaxes muscles |
| Botox | exocytosis blocker selective cholinergic uptake | hyperhydrosis (increased sweating/perspiration) muscle spasm |
| Butoxamine | β2-adrenoceptor antagonist | experimental pharmacology |
| Carbachol | (synthetic) muscarinic and nicotinic agonist | relaxes smooth muscle eye/ophthalmic purposes like glaucoma |
| Carbidopa | inhibitor of DOPA decarboxylase | Parkinsons |
| Clonidine | partial α2-adrenoceptor agonist | hypertension (high BP) |
| Darifenacin | M3-selective muscarinic antagonist | reduce urinary frequency |
| Diclyomine | non-selective muscarinic antagonist | irritable bowel syndrome |
| Distigmine | medium duration anticholinesterase | inhibits breakdown of ACh in synapse, so prolongs it's effecs on the postsynaptic receptors |
| Dobutamine | β1-adrenoceptor agonist | cardiogenic shock cardiac surgery |
| Ecothiopate | irreversible anticholinesterase | glaucoma (eye drops - reduce intraocular pressure within eye) |
| Ephedrine | indirectly acting sympathomimetic | nasal congestion - relaxes airways stimulant - speeds up heart and nervous system |
| Guanethidine | blocks NA realease | hypertensive crisis (high BP, impairing 1+ major organ system) |
| Hemicholinium | presynaptic ACh uptake blocker | decreases production of ACh - so is an indirect ACh antagonist. No clinical use - but used in research experiments |
| Hyoscine | non-selective muscarinic antagonist | premedication before surgery GI spasms motion sickness |
| Ipratropium | non-selective muscarinic antagonist | asthma - relaxes airways by inhibiting constriction of smooth muscles |
| Isoprenaline | non-selective β-adrenoceptor agonist | shock |
| Labetalol | non-selective α1, β1-2 antagonist | hypertension (high BP) |
| Methyldopa | partial α2-adrenoceptor agonist precursor | hypertension (high BP) in pregnancy |
| Muscarine | non-selective muscarinic agonist | favours rest and digest |
| Neostigmine | medium duration anticholinesterase | constipation - contracts GI tract smooth muscles |
| Nicotine | nicotinic AChR agonist | |
| Noradrenaline (NA) | non-selective adrenoceptor agonist | neurotransmitter |
| Oxotremorine | non-selective muscarinic agonist | experimental pharmacology |
| Phenoxybenzamine | irreversible α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline) |
| Phentolamine | α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline) |
| Phenylephrine | α1-adrenoceptor agonist | nasal congestion acute hypertension (high BP) |
| Pilocarpine | non-selective muscarinic agonist | glaucoma dry eyes mouth |
| Pirenzepine | M1-selective muscarinic antagonist | peptic ulcer |
| Prazosin | α1-adrenoceptor antagonist | hypertension (high BP) prostatic hyperplasia (enlarged prostate) |
| Propanolol | non-selective β-adrenoceptor antagonist | hypertension (high BP) anxiety migraine |
| Reserpine | vesicular monoamine uptake blocker | experimental can cause depression/hypotension |
| Salbutamol | β2-adrenoceptor agonist | asthma (short term) premature labour |
| Salmeterol | β2-adrenoceptor agonist | asthma prophylaxis |
| Timolol | non-selective β-adrenoceptor antagonist | hypertension angina migraine glaucoma |
| Tropicamide | non-selective (but M4 prefering) muscarinic antagoninst | eye examinations |
| Tyramine | amino acid responsible for cheese reaction | |
| Vesamicol | vesicular ACh uptake blocker | |
| Yohimbine | α2-adrenoceptor antagonist | aphrodisiac? |
| α-Methyltyrosine | inhibitor of tyrosine kinase | |
| Atenolol | β1-adrenoceptor antagonist. | hypertension (high BP) angina (narrowing of coronal arteries) arrhythima (irregular heart beat) |
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