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Ch. 39 questions
Acquired Immonodeficiency Syndrome
| Question | Answer |
|---|---|
| What is a retrovirus? | have the enzyme reverse transcriptase-synthesizes DNA from an RNA template,a reverse transcription |
| What is so unusual about the reverse transcriptase? | enzyme can replicate a double strand of DNA from a single strand of RNA |
| What is the receptor for HIV attachment to cells, and what cells have this receptor? | HIV attaches to the T cell receptor in CD4 or Th cells |
| Discuss the transmission of HIV | infection requires access to recipient's bloodstream via cut or tear in skin-which is exposed to semen, vaginal fluids, or blood |
| When do overt symptoms of AIDS appear? | 8-10 yrs after initial infection with HIV or when CD4 cell count drops to less than 200cells/mm |
| How does the genome of HIV persist in certain human cells? | genome of HIV persists in certain human cells because reverse transcriptase makes DNA ccopy-intigrates to become part of cell genome |
| What actually kills AIDS patients? | CD4 cells gradually reduced to zero-prevents formation of memory cells-expanded cell population of any immune cells--opportunistic infections can't be surmounted by immune system |
| what is the relationship between AIDS and Kaposi's sarcoma | high incidence of Kaposi's sarcoma in AIDS pts due to reactivation of the human herpes virus 8 |
| How can the spread of AiDS be reduced? | if people avoid anal sex, do not have multiple sex partners, avoid recapping needles, use condoms, abstinence, single sex partner, use gloves/proper face/eye covering if mucous membrane exposure possible |
Created by:
heatherlvn
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