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Ch. 10 Vocabulary


Adsorption attachment process--virus sticks to the surface of the host cell
Attachment factor (key)host cell receptor and attachment coponents--lock & key in which the key can only recognize cell types that carry the correct lock
Bacteriophage bacterial viruses--cause a hole in the layer of bacteria in a petri dish by killing the bacteria
Capsid protien coat of a virus-
Capsomere protein subunits of a capsis--
Carcinogenic viruses that induce or generate cancer
Cell killing when cells are killed by virus growth in an area
Cytopathic effects clinical specimen collected--placed on human cells in a tissue culture and watch for changes in the cell--(CPE)
Enveloped virus virus with an envelope--most nucleocapsids are icosahedral/helical
Glycoprotein surface protein of virion--has a specific attachment site--binds to specific receptor on types of cells the virus infects
Host factory supply enzymes and building blockes to propagate new virions--viruses can't produce their own energy for growth
Inclusion bodies microscopically observable dark areas of virus particles that accumuate on culture dish
Luekemias (leuko--white)--cancers in cells that freely move around normally occur in white blood cells
Lyse lytic viruses--break open the cell
Lysogens DNA of DNA viruses integrate into host cell DNA--divide with the cell but lyse the cell under certain conditions--(proviruses)--have potential to become lytic
Naked virus viruses without an envelope--most nucleocapsids are icosahedral/helical
Nucleocapsid nucleic acid plus the protein coat of a virus
Obligate intracellular parasites incapable of growing outside a host cell
plaque area with no living cells--observed as a hole in the cell layer--info is useful in lab--plaques on a dish can be counted to quantify # of virions in a sample
Provirus (lysogens)--have the potential to become lytic--DNA of DNA viruses integrate into host cell DNA--divide with the cell--can lyse the cell under certain conditions
Receptor cell types that carry the correct lock for attachment factor of viruses
Retrovirus exception to general viruses--carry out transcription in reverse--carry 2 copies of the RNA genome
Reverse transcriptase (RT)--RNA dependent DNA polymerase--uses viral RNA as template to produce duplex DNA copy--integrated into the host chromosome--host transcription/translation machinery can express the viral genes
Round up host cells no longer adhere tightly to the bottom of the tissue culture dish--can be seen with microscope
Syncytia formation viruses that cause cells to fuse together into giant cells
Transformation type of CPE where tumor cells keep growing until piles of cells are visible in the dish--same mechanism involved when tumor cells grow uncontrollably or metastasize
Tumor a solid or tissue cancer
Tumorigenesis viruses that induce tumors--
virions complete virus particles
Virus simplest organism on Earth--contain 2-50 genes--can't code for all molecular biology processes-translation which requires 90 genes--can't produce their own energy for growth
Virus particle any virus with its appropriate coating layer--virion--refer to physical structures--viruses aren't cells--nucleic acid may be DNA/RNA not both--nucleic acid may be single/double stranded--
Created by: heatherlvn