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Heart Failure

Drugs recognition: chap 12

digoxin (Lanoxin) Positive Inotropic (increases strength of contraction)
digoxin immune Fab – antidote for digoxin toxicity Positive Inotropic (increases strength of contraction)
ACE inh Vasodilators
ARB’s Vasodilators
hydralazine (Apresoline) Vasodilators
isorobide dinitrate (Isordil) Vasodilators
spironolactone (Aldactone) Aldosterone Antagonists
eplerenone (Inspra) Aldosterone Antagonists
carvedilol (Coreg) Beta Blockers
metoprolol (Lopressor, Toprol XL) Beta Blockers
bisoprolol (Zebeta) Beta Blockers
furosemide (Lasix) Diuretics
bumetanide (Bumex) Diuretics
torsemide (Demadex) Diuretics
bumetamide reduce edema and congestion
furosemide reduce edema and congestion
torsemide reduce edema and congestion
what lead to cardiac remodeling angiotensin II and sympathetic activation
what does cardiac remodeling do reduce systolic and diastolic function
what do drugs of positive inotropic do? increase cardiac output by increasing cardiac contractility
drugs used to prevent cardiac remodeling angiotensin inhibitors and B- blockers
digitalis absorption inhibited by antacids and cholestyramide
digitalis clearance reduced by diltiazem, verapamil, and quinidine
diuretic-induced hypokalemia precipitates (worsen) digitalis toxicity
carvedilol indication heart failure
carvedilol adverse effects light-headedness, dizziness, bradycardia, worsening of heart failure (vasodilation, and decreased blood pressure)
carvedilol class block a and b- adrenoceptor, antioxidant
B-blockers moa Reduce excess sympathetic stimulation
Aldosterone Blockers moa Increase Na excretion, decrease K excretion, mild diuresis
Aldosterone Blockers adverse actions Hyperkalemia,Gynecomastia,Impotence
a pt complaining of nausea, vomiting, blurred, abnormal-colored vision, and palpitations adverse effects of digoxin
positive inotropic increase contractility
Created by: prinluu