Rheumatoid Arthritis Word Scramble

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Question	Answer
Pathophysiology of Rheumatoid Arthirtis	From longterm exposure to unknown antigen, genetically. They target synovial membranes, Then leukocytes- go to area and degrade synovial tissues and cartilage. Immune response is↑,
Rheumatoid Factors	Antibodies that present in RA
Pannus	An abnormal tissue layer that includes new formed blood vessels, that may develop within the synovial membrane, leading to greater loss of bone and cartilage. This leads to scar tissue.
Risk Factors for RA	Family HX, smoking, obesity, physical, emotional trauma, air pollution, insecticides, and occupational exposure,
Manifastations	Elderly- hard to distinguish between osteoarthritis and RA. redness, warmth, pain welling and deformities, ↓appetite, fever, fatigue, anemia, sleep patterns, quality of life, emotional.
Swan Neck Deformity	Hyperextension of the PIP joints, Boutonniere Deformity
Respiratory	pleural disease, interstitial fibrosis, pneumonitis
Cardiovascular	Vasculitis, Pericarditis
Metabolic	Fatigue, weakness, anorexia, weight loss, ↓ fever
Integumentary	Rheumatoid Nodules
Exocrine	Dry eyes/mouth
Musculoskeletal	joint swelling, redness, warmth, pain, tenderness, morning stiffness, cervical pain, neuro. , limited ROM, Deformity, carpal tunnel syndrome, Ulnar deviation, swam-neck deform, joint effusion (Fluid in joint area) unstable, pain from moving
Concept of RA	Immunity
Interrelated Concepts	Confort, Pain, Clotting
Typical Age Ranges	40-60 .
Epstein Barr Virus	Highest link between that and RA
Genetics	50% RISK, 60% with the disease have Human Leukocyte Antigen (HLA)-DR4
Assessment: Noticing	Look for signs; joint swelling, pain, warmth, deformity . Also look for fever, anorexia, fatigue Psychosocial, Labs- RA factor, antinuclear-antibody titer, ESR, serum complement, serum protein, immunoglobulins, CT, Xray, arthrocentesis, bone scan
Most Commonly Effected	Hands and Feet
Not limited to Joints	Anemia, multisystem effects, Can have periods of remission
Complications	weight loss, fever, fatigue, periods of exacerbations, subQ nodules, Resp. & cardiac complications, Vasculitis (inflammation of the blood vessels), periungual (lesions on finger/toenails), paresthesia (burning hands/feet)
Associated Syndromes	Sjogren's Syndrome (dry eyes/mouth) Felty's Syndrome Caplan's Syndrome
Analysis: Interpreting	Chronic Inflammation,↓ mobility, potential for↓self-esteem
Planning and Implementation: Responding	Management of chronic inflammation and pain by meds, and supplements
Pharm Therapy	DMARDS- disease modifying anti-rheumatic drugs (methotrexate), NSAIDS, BRMS- biological response modifiers (Humara- helps with↓signals of inflammation.
Other Pharm Therapy	Glucocorticoids, immunosuppressive agents, Supplements- calcium, omega 3, linolenic acid, WATCH for kidney stones from calcium, omega 3- can interfere with clotting
Non Pharm Interventions	Rest, proper positioning, ice/heat, plasmapheresis (helps with↑ levels of CRP, surgery, complementary and integrative therapies, promotion of self-care, management of fatigue,↑body image . Hydrotherapy
Promote Mobility	Independence- adaptive devices, splints/braces, walkers/canes wheelchair, Encourage movement . Combat Fatigue- physical therapy, conserving energy
Juvenile Idiopathic Arthritis	Unknown Cause in children, Inflammation lasting longer than 6 weeks, and one or more joints. Dx ↓ 16
Pathophysiology JIA	unknown but thought to have a autoimmune link joint inflammation that leads to scar tissue and limited ROM. Altered growth of the epiphyseal plates
Incidence of JIA	onset between 3-6 years of age & around puberty. occurs more often in males than females. 1-1000 kids in the US
Manifestations of JIA	Symptoms- fever, rash, lymphadenopathy (swollen lymph nodes), Splenomegaly/Hepatomegaly (enlarged spleen/liver), Joints-↓ mobility, swelling, pain, gait differences
Tests for JIA	No definitive confirmation for it, ESR and CRP are beneficial for determining amount of inflammation; RA, ANA X-rays, r/o other causes (fractures) Monitor joint damage and bone development
Treatment:Planning	Control Inflammation (also pain), Pain, Preserve function, Prevention of deformities, Remission, ↓side effects of disease, splints for promoting bone growth
Pharm Therapy for JIA	NSIADS -(↓inflammation/pain), Ibuprofen, naproxen, Indomethacin, Meloxicam DMARD- methotrexate Steroids- Prednisone, methylprednisone
Nursing Care	Promote mobility, ROM with Stretching/hydrotherapy Encourage adequate nutrition Educate the PT

Created by: harley_chevy_girl