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Cell Phys Chap 16 Test

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1.
actin filaments and microtubules assemble (__________) and disassembly by the addition and removal of subunits (_______) at the end of the polymer
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2.
________ of the bound nucleotide reduces the binding affinity of the subunit for neighboring subunits making it more likely to dissociate from each end of the filament
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3.
two-stranded helical polymers of actin protein subuinits
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4.
ATP or GTP that is hydrolyzed must be replenished by a _____ _____ _____ of the free subunit creating a steady state. diphosphate --> triphosphate
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5.
the motor protiens that move on microtubules are either members of the _____ _____ or the _____ _____
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6.
actin binds ___
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7.
some ________ ______ assemble filaments into larger ordered structures by cross-linking them to one another in geometrically defined ways
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8.
Lateral side arms of a microvillus are composed of ______ and ______. They connect the sides of the actin filament bundle to the overlying plasma membrane
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9.
Different subunit inretactions are broken when a subunit is lost at either end
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10.
eacg actin molecule carries a tightly bound ____ that is ydrolyzed to ___ soon after assembly into the polymer
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11.
latrunulin
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12.
other types of this cytoskeleton filament extend across the cytoplasm gining cells mechanical strength
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13.
long, hollow cylinders made of tubulin subunits; outer diameter of 25 nm
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14.
what are the main types of myosin?
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15.
________ are the largest of the known molecular motors, and they are also among the fastest. They are independently evolved and have distinct structure and mechanism of action. (can move microtubules in test tube 14 mm/sec)
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16.
function of microtubules
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17.
some accessory proteins alter filament dynamics by _____ to the ends of filaments or _____ the filaments into smaller fragments
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18.
Dyenin movement is from ________ to _________
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19.
the rate of loss is given by ____ which has units of ____
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20.
As the polymer grows, subunits are used up, and C is observed to _____ until it reaches a constant value called the _____ _____
A.
accessory proteins
B.
kinesin superfamily or the dynein family
C.
nucleotide exchange reaction
D.
false (exactly the same subunit)
E.
actin filaments (microfilaments)
F.
myosin I and the Ca2+ binding protien in calmodulin
G.
positive to negative
H.
Dyneins
I.
ATP; ADP
J.
determine the positions of membrane-enclosed organelles and direct intracellular transport
K.
binding; severing
L.
drop; critical concentration
M.
(polymerize); (monomers)
N.
ATP
O.
intermediate filaments
P.
Koff; sec-1
Q.
hydrolysis
R.
microtubules
S.
myosin I (located in microvilli) and myosin II ( motor head for muscle contraction)
T.
actin-specific drug that binds subunits and prevents their polymerization
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21.
the only structural element shared among all members of each superfamily is the motor _____ domain
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22.
Microtubules depolymerize about 100 times faster from an end containing ____ tubulin that from one containing ____ tubulin
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23.
huge multinucleated cells form by the fusion of many muscle cell precursors, called ________
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24.
At the apical (upper) surface, facing the intestinal lumen, bundled actin filaments form ______ that increase the cell surface area available for absorbing nutrients from food
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25.
the formation of ______ _______ from much smaller protein subunits allows regulated filament assembly and disassembly to reshape the cytoskeleton
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26.
for ______ nucleation tthe nucleus is larger and has a more complicated structure consisting of a ring of 13 or more molecules
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27.
in epithelial tissue, they span the cytoplasm from one cell junction to another, strengthening the entire epithelium
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28.
______ _______ undergo dynamic instability, growing and shrinking at their plus ends
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29.
in isolated doublet microtubules dynein produces ______ ______
Type the Question that corresponds to the displayed Answer.
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30.
actin-specific drug that caps filaments plus ends

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