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A2 Chemistry OCR (B)

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Instantaneous dipole - induced dipole bonds   a dipole is formed from the uneven distribution of electrons over a molecule. This dipole induces a dipole in another molecule  
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electronegativity   a measure of the attraction of an atom for a pair of electrons in a covalent bond. F is the most electronegative followed by O, N, Cl and Br.  
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permanent dipole - permanent dipole bonds   attractive forces between polar molecules  
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hydrogen bonds   attractive forces between the lone pairs on an O, N or F and a delta positive hydrogen  
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enthalpy change of solution   the enthalpy change when one mole of a solute dissolves to form an infinitely dilute solution. Insoluble compounds have a positive value, soluble compounds have a negative value  
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lattice enthalpy   the enthalpy change when one mole of a solid lattice is formed from its gaseous ions  
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enthalpy change of hydration   the enthalpy change when a solution of ions is formed from one mole of gaseous ions. It always has a negative value  
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strong acid   an acid which fully dissociates in water. Has a strong tendency to donate protons  
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strong base   fully dissociates in water  
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weak acid   only partially dissociates in water  
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buffer solution   a solution which can resist changes in pH on the addition of small amounts of acid or alkali  
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addition reaction   where 2 or more molecules react to form a single larger molecule  
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condensation reaction   two molecules react together to form a larger molecule with the loss of water  
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elimination reaction   reaction of 2 molecules to form a larger molecule with the elimination of a smaller molecule (usually water or HCl)  
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substitution reaction   when one functional group in an organic molecule is substituted for another one  
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oxidation   loss of electrons, increase in oxidation number, reaction with oxygen, removal of hydrogen  
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reduction   gain of electrons, decrease in oxidation number, reaction with hydrogen, removal of hydrogen  
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hydrolysis   reaction with water or hydroxide ions  
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radical   a species with an unpaired electron  
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electrophile   a positively charged ion or a molecule with a delta positive charge that will be attracted to a negatively charged area and react by accepting a lone pair of electrons to form a covalent bond  
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nucleophile   a molecule or negatively charged ions with a lone pair of electrons that it can donate to a positively charged atom to form a covalent bond  
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carbocation   a positively charged carbon atom  
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saturated   contains single bonds only  
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unsaturated   contains multiple bonds  
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Pharmacophore   functional group(s) that determine the pharmacological (curing) activity of the molecule, makes it a successful medicine.  
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Receptor site   a specific set of functional groups that can bind one only molecule, which is complementary (stereospecific) to the site. Usually the receptor site can bind a specific optical or geometric isomer.  
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Lead compound   a compound that shows some promise in curing a disease. This compound can further be modified to produce better results  
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Molecular recognition   this is the group of atoms that is involved in binding to the receptor. The structural fragment fits precisely into the shape of the receptor, and functional groups on both are correctly positioned to interact.  
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Chromophore   part of the molecule responsible for colour. Usually has conjugated electrons or extended delocalised system. Functional groups such as –NH2, -OH, -NR2 are often present. They also contain lone pairs that can get involved in the delocalised system.  
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