Fat soluble vitamins
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Vitamin E is also called | show 🗑
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show | Alpha-tocopherol
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show | hemolytic anemia
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In children, vitamin D deficiency can result | show 🗑
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In adults, vitamin D deficiency --> | show 🗑
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Principle function of vitamin D | show 🗑
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fat soluble vitamins include... | show 🗑
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show | bile & dietary fat
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show | night vision, cell differentiation, growth regulation
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Preformed vitamin A compounds= | show 🗑
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show | carotenoid
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what has activity of vitamin A? | show 🗑
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Retinoids and carotenoids are transported from the intestine in | show 🗑
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show | retinol
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vitamin A form that circulates in blood | show 🗑
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show | retinal
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show | retinoic acid
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show | retinal (but no converting back!)
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Carotenoids that are not converted to vitamin A may act as | show 🗑
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in eye, retinal combines with _____ to form _____ | show 🗑
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show | transform the energy from light into a nerve impulse that is sent to the brain (interprets as vision)
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rhodopsin embedded in ____ cells | show 🗑
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show | retinoic acid enters nucleus, binds to specific protein receptors
-RA receptor binds to regulatory region on DNA
--> alters level of mRNA produced
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show | growth and development, embryogenesis and the IMMUNE system
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vitamin A deficiency caused by | show 🗑
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show | liver, fatty fish, fish oils and egg yolks
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Vitamin D is important for..... | show 🗑
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show | parathyroid gland releases parathyroid hormone (PTH)
--> kidney to activate enzymes to convert 25-hydroxyvitamin D3 to active form, 1,25-hydroxyvitamin D3
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show | -increase calcium transport proteins in intestines (move Ca from intestine to body)
-in bones, stimulate release of Ca by bone breakdown
-in kidney, increase amount of Ca retained by kidneys and put back into the blood
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show | genes regulating bone health, immune response, reproductive functions, and skin growth.
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though rare, individuals at risk for vitamin E deficiency are... | show 🗑
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show | Koagulation (danish for coagulation)
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show | phylloquinone and menaquinones
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show | -phylloquinone in plants (leafy green vegetables)
-menaquinones in fish oil, meats and synthesized by bacteria in the human intestine
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show | -blood clotting
-Involved in proteins needed for bone mineralization and demineralization
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show | -results in abnormal blood coagulation
-common in newborns (little transfer to fetus by mother, low vitamin K in breast milk)
-infants given vitamin K injection right after birth
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retinoids & cartenoids transportation | show 🗑
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some cartenoids converted to ______ in ___________ | show 🗑
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show | retinol must bind to RETINOL-BINDING PROTEIN
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vitamin D from sunlight/ food --> active form | show 🗑
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show | increase calcium absorption from INTESTINE
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show | stimulate PTH increase bone breakdown; stimulates kidney to activate enzymes convert 25-hydroxyvitamin D3 to ACTIVE form; KIDNEY increase calcium retention
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show | • Active vitamin D binds Vitamin D receptor proteins @ target tissues → affect gene expression
o Increase blood calcium levels
o Targets= intestinal cells, bone, kidney
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show | rickets (children), osteomalacia (adults)
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where vitamin E works as antioxidant | show 🗑
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show | DONATES e- to eliminate free radicals, Vitamin C restores antioxidant functions (gives back e-)
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why infants need shot of vitamin K | show 🗑
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show | uncontrolled bleeding
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