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PSYC 271 Midterm 2

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
        Help!  

Question
Answer
show Ions  
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show Difference in the concentration of charges between two solutions  
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show electrostatic pressure  
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4 important ions for neural conduction   show
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show Voltmeter, or oscilloscope with electrical stimulator  
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____ concentration is higher outside of the cell   show
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____ concentration is higher inside the cell   show
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Na is driven in by both ______ _______ and its _____ _____ (random motion)   show
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show IN, OUT  
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show active force (ATP) that exchanges 3NA+ inside for 2K outsode  
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EPSP causes ______, and an ______probability of action potential. Ie Na or Ca influx   show
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show hyperpolarization, decreased  
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PSPs are _______, and they are transmitted ______ and ______   show
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show less negative, closer, more  
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show more negative, further, less  
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What is typically needed to cause a neuron to fire?   show
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In order to generate an AP, the ______ of _____ must be reached near the axon   show
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show -65mV  
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3 examples of spatial summation of PSPs   show
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Temporal summation of PSPs   show
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Steps in ionic basis of action potentials:   show
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Resting membrane potential:   show
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Depolarization   show
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show point that voltage gated sodium channels open, AP occurs  
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show membrane potential becomes negative again, approaching the resting membrane potential  
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Hyperpolarization:   show
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show backward  
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Absolute refractory period:   show
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show Threshold less negative than rest, more difficult to initiate another AP (more depolarization necessary)  
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show active, slower, nondecremental  
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Diffusion of Na+ triggers next ___ ____   show
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show Na  
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show to  
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Antidromic conduction is transmission   show
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show saltatory conduction  
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show Myelinated, larger  
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show squid, different, mammal cerebral  
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Fo interneurons fire action potentials?   show
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Are dendrites able to fire action potentials?   show
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Mammal cerebral action potentials vary in ____, ______, and ______   show
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Can mammalian cerebral axons fire potentials in the absence ofinput?   show
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Axoaxonic synapses   show
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show bidirectional  
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show rare  
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show synapses between axon shafts - parallel side by side, synapse onto other  
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show common for monoamine neurotransmission - diffuse release of NT  
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Some communication is through ____ _____ between cells   show
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_____ appear to modulate neuronal activity within their own domain   show
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show cytoplasm of axon terminal buttons  
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show packaged into synaptic vesicles by golgi complex at terminal button  
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show in cytoplasm of cell body by ribosomes  
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Packaging of large molecule neurotransmitter   show
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Transport of large molecule neurotransmitter   show
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show small, large, each  
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show AP arrives at terminal button, voltage gated calcium channels open, Ca++ enters, vesicles fuse, empty contents via exocytosis  
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Ionotropic receptors AKA ______ or _______   show
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Ionotropic receptors are ____ acting   show
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Ionotropic receptirs usually have a _____ effect   show
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Depending on the type, Ionotropic receptros can _____ or _____   show
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Metabotropic receptors AKA   show
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Metabotropic receptors are usually ____ acting   show
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Metabotropic receptors have a ____ effect by modifying ___ ____   show
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show neurotransmitter, neurotransmitter  
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Neurotransmitter reuptake   show
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Neurotransmitter degradation by enzymes   show
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show Amino acids, monoamines, acetylcholine, unconventional neurotransmitters, neuropeptides  
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AA NTs   show
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show more diffuse, non-directed synapses. Metabotropic receptors with diverse functions, arise in brainstem. Catecholamines, indolamines  
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Ach NTs   show
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What defines something as an unconventional neurotransmitter?   show
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show Soluble gases that exist only briefly, endocannabinoids  
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Soluble gases that exist only briefly   show
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show produced on-demand, released from dendrites, inhibit presynaptic neurons. rapidly degraded  
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Neuropeptides are ____ ______ of amino acids   show
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show variety  
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show Endorphins ie Endogenous opiods, analgesia/reward system  
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show Facilitate neurotransmitter's effects  
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Antagonists   show
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Drugs may impact ___ _____ of the synaptic transmission pathway   show
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Agonist drug effect on synthesis   show
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show Blocks synthesis of NT molecule  
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Agonist drug on breakdown   show
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show NT molecules leak from vesicles, destroyed by degrading enzymes  
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Agonist drug on exocytosis   show
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Antagonist drug on exocytosis   show
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Agonist drug on inhibitory feedback   show
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Antagonist drug on inhibitory feedback   show
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show binds to postsynaptic receptor, activates/increases effect on NT molecule  
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show receptor blocker, binds to postsynaptic receptors to block NT effect  
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show blocks deactivation of NT, blocking degradation or reuptake  
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Antagonist drug on deactivation   show
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show acetylcholine receptor subtypes, endogenous opioids, antipsychotic drugs  
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Historically, we used to think that each NT had ___ kind of receptor   show
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Different _____ selective to specific _____ subtypes, exerting different effects despite involving the same NT   show
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show Different locations, receptor function, and behavioural effects  
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show Activation at neuromuscular junction stimulates muscle contraction  
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show Activation slows heart and constricts pupils in ANS  
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Ancient Greeks would consume _____ extracts for stomach ailments and pupil dilation   show
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The PNS releases ______ on _______ receptors within iris sphincter muscles to constrict pupils   show
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_____, the main active ingredient of belladonna, blocks _____ receptors, blocking Ach effect on pupils   show
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_______: Extract of certain vines used by South American natives as a paralytic poison for darts in hunting and war   show
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Curare blocks _____ receptors at the neuromuscular junction, causing _____   show
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show no muscular movement during surgery, but artificial respiration needed  
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Extracted toxin of botulism bacteria   show
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show acetylcholine, tremors, wrinkles  
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show brain mechanisms of pleasure and pain  
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show Opium  
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Main active ingredient in Opium is _____, an analgesic   show
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show PAG  
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show Analgesia  
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show Endorphins  
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"in the head" opiates   show
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show Parkinsonian-like  
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Parkinson's disease associated with death of what? Where?   show
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______ _____, such as cocaine and amphetamines can induce and exacerbate phycosis   show
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Dopamine antagonists can _____ psychotic symptoms   show
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What are 2 X-ray based research techniques?   show
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show PET and SPECT  
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What are 3 magnetic field-based research techniques?   show
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show Dense, softer  
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Are X rays normally useful for neuroimaging? Why or why not?   show
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show skull and bone fragments, foreign objects  
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show carcinogenic  
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show 2D  
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show radio-opaque, absorbs  
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_____ ______ is excellent at imaging blood vessels   show
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show multiple angles, 3D  
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show Relatively low  
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Health effects of CT better or worse than X-ray? Why?   show
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show local blood flow  
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show positrons  
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Typical examples of radiolabelled tracers used in SPECT   show
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show Intravenously  
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SPECT has very _____ temporal resolution   show
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show specific substances  
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show Alzheimers - decreased temporal-parietal metabolism  
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PET has the same features as SPECT, except what?   show
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PET tracers have longer or shorter half lives than SPECT?   show
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show 2-DG, taken up by active NTs (not metabolized) anywhere glucose is taken up  
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Why is PET expensive   show
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PET tracers are usually administered ____ or ____   show
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Pet has ____ spatial and temporal resolution than SPECT, but is more expensive   show
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Constructed image from measures electromagnatic signals emitted by H atoms as they return to alignment with a strong magnetic field after a radio-frequency burst   show
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MRI has very ____ resolution 3D images   show
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There is high ____ between white and gray matter in MRIs   show
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What can MRIs be combined with? Examples?   show
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Exceptions to MRI safety/non-invasiveness   show
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show fMRI  
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show Cognitive activity  
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what response does fMRI measure?   show
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What can fMRI be used to detect alongside BOLD?   show
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show Paired-image subtraction/ controls for external thought, isolates for actual elucidated response  
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show Low frequency fluctuations, regional homegeneity  
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Diffusion Tensor Imaging measures pathways along which ____ _____ rapidly diffuse   show
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show connected  
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fUS imaging   show
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show blood volume  
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show passage  
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show cheap, prtable, useful for those who can't use PET or MRI  
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show lesions  
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fMRI signals is a process that occurs many times/second, so signals can be _____ to one another   show
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The default mode network is _____ _____ throughout the brain   show
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What is the default mode network?   show
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Default mode network is a source of ____ ____, actively unrelated to a task   show
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show near-infrared light  
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fNIRS involves measuring changes in _____ and ____________ concentration   show
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Measures electical activity on the scalp and is a reflection of neuronal synchrony   show
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show epilepsy, temporal, spatial  
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EEG measures the ______ of brain waves   show
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show Increasing the number of electrodes  
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show event-related potentials  
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EEG _______ cancels out after a certain amount of trials   show
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Early EEG components are usually related to ______ features (exogenous components)   show
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show cognitive  
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show Far Field Potentials  
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show Magnetoencephalography  
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show heavily insulated  
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brain electrical currents create _____ _____ _____   show
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show coils  
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Pros of MEG   show
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measures the changing difference in the voltage between two large electrodes placed on the skin above a large muscle   show
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What does EMG measure?   show
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What is electrooculagraphy (EOG)?   show
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EOG has been replaced by what?   show
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The general level of skin conductance associated with a particular situation   show
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A rapid change in skin conductance in response to a particular event   show
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Example of skin conductance response uses?   show
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show Heart rate  
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Blood pressure is measured via a   show
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show Plethysmography  
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show decreases  
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If behaviour from TMS is disrupted, that means what?   show
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Transcranial electrical stimulation _______ brain function by passing ____ _____ through the cortex   show
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In tES, is the current strong enough to elicit an action potential?   show
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How does transcranial direct current stimulation work?   show
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show electrodes  
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show frequency, strength  
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show frequency  
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tRNS has different effects depending on _____ of stimulation   show
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show animal  
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Stereotaxic surgery uses stereotaxic ______ and instrument   show
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show lesions, probes, electrodes  
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In a _______ lesion, tissue is sucked up into a pipette   show
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What remains behind following an aspiration lesion? why?   show
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________-________ lesions occur when high-frequency currents are administered through the tip of an electrode   show
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show heat  
🗑
Radio frequency lesions everything where?   show
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Knife cut lesions are useful for _____   show
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show inactivate  
🗑
show Lidocaine, cold  
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Excitotoxic lesions excite neurons past the point of what?   show
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show tracts and blood vessels  
🗑
show more  
🗑
show compensates for  
🗑
show localization  
🗑
show Unilateral, bilateral  
🗑
What kind of stimulation typically has the opposite effect of lesions?   show
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Intracellular unit recording measures changes in the ___ _____ of a neuron over time, requiring a ______ positioned inside a neuron   show
🗑
show Hard to keep microelectrode inside neuron  
🗑
show near  
🗑
show spikes, action potential  
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show amplitude  
🗑
show rate of firing  
🗑
Invasive EEG uses electrodes where?   show
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show more accurate recordings than normal (scalp) EEG  
🗑
The route of drug administration influences the ____ and _____ to which the drug reaches its site of action   show
🗑
Difficulties of oral ingestion in non-human subjects?   show
🗑
Absorption via the digestive tract is _________   show
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show capillaries  
🗑
show regulation can be difficult, can damage lungs  
🗑
Absorption through mucous membrane entry points:   show
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show digestive tract  
🗑
show Intraperitoneally  
🗑
show Subcutaneously  
🗑
show Intramuscularly  
🗑
show Intravenously  
🗑
______ injection is injection into CNS   show
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Central injection bypasses digestive tract and ____ ____ _____   show
🗑
Into a ventricle to affect the whole brain   show
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Autoradiography measures the location of _______ of interest when the brain is active during an _____   show
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Difference between PET scan and autoradiography   show
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show vivo  
🗑
show antibodies  
🗑
show mRNA/DNA  
🗑
Organisms lacking a ______ of interest   show
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Replacing one gene with another gene   show
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CRISPR/Cas9 edit genes at a particular time of ______-   show
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Optogenetics is the combination of _______ and _____ methods to achieve gain or loss of function in specific cells of living tissue   show
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Current neurophychological assessments focus more on the ______ of a patient   show
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Brain scanning is best at _____ _____ or metabolic disturbances, but lack ______ to other problems   show
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show No  
🗑
What is a standard battery of neuropsychological tests?   show
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Problem with the standard battery of neurophychological tests?   show
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What is the HRB test?   show
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HRB Category Test   show
🗑
show placing varied shapes in holes without sight  
🗑
show detect similarities and differences between rhythms  
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HRB speech sounds perception test   show
🗑
show Tap index finger as fast as possible for 10 seconds  
🗑
show tests visual attention and task switching  
🗑
show Tests motor difficulties of each hemisphere  
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Customized test batteries are used to measure ________, with more precise tests used in follow-ups   show
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show modern theories  
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Cognitive _____, not just performance is measured in customized test batteries   show
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3 tests of the common neuropsychological battery measure what?   show
🗑
show general verbal skills including verbal fluency, relies on prior knowledge  
🗑
show examines a problem, drawing upon visual motor/spatial skills  
🗑
show hold information so it can be used to solve a problem  
🗑
show focus attention, quickly scan, discriminate between, and sequentially order visual information  
🗑
How do they measure which hemisphere is dominant for language?   show
🗑
What is species common behaviours?   show
🗑
What do the open field tests and the elevated plus maze test for   show
🗑
What are the three measures of emotionality   show
🗑
In the colony-intruder paradigm, rats are placed in a chamber with a _________,_________ rat   show
🗑
show lordosis  
🗑
How to measure sexual behaviour in male rats   show
🗑
show step-by-step process, temporal continuity, principle of equipotentiality  
🗑
show spatial  
🗑
show anti-anxiety  
🗑
show sensitivity and acuity, iris  
🗑
The lens focuses light on the _________, in a process called _________   show
🗑
When the lens is cylindrical, focus is on a _________ object   show
🗑
When the lens is flattened, focus is on a _________ object   show
🗑
Most of what is seen is seen through _________ eyes   show
🗑
show closer, depth perception  
🗑
show front  
🗑
show side  
🗑
show 5  
🗑
the fovea has high _________ vision   show
🗑
optic disk involves the _________ spot and _________   show
🗑
show no, some can see in very little light  
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Wavelength is associated closely with the perception of   show
🗑
intensity is closely associated with the perception of   show
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_________ is the turning of the eyes slightly inward when looking at something nearby   show
🗑
In the retina, the cells at the _________ are the first to detect light   show
🗑
show inside-out  
🗑
show cell  
🗑
show five  
🗑
Receptor layer of the retina   show
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show lateral communication  
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amacrine cell later of retina   show
🗑
show high-acuity  
🗑
show thinning, distortion  
🗑
the optic disk is where axons of _________ ganglion cells penetrate _________, exit eye through optic nerve   show
🗑
show different kinds of vision  
🗑
show phototopic, high-acuity  
🗑
show scototpic, high-sensitivity, detail  
🗑
show low  
🗑
show high  
🗑
show cones  
🗑
show neither  
🗑
show spectral  
🗑
show saccdes  
🗑
the visual system responds to _________   show
🗑
show conversion  
🗑
show light  
🗑
Visual transduction information is transmitted via   show
🗑
What is the pigment found in rods?   show
🗑
Rhodospin is a receptor that responds to _________ rather than NTs   show
🗑
In the dark, rhodopsin Na+ channels are partially _________, (partial _________), _________ glutamate   show
🗑
show close, hyperpolarize, inhibiting  
🗑
In both eyes, left hits _________ and right hits _________   show
🗑
Each eye only processes _________ of visual field, contralaterally   show
🗑
The _________ hemiretina of each eye connects to the _________ lateral geniculate nucleus,   show
🗑
Magnocellular layers have _________ cell bodies, are the _________ 2 laters of LGN   show
🗑
Magnocellular bodies are particularily responsive to _________, input primarily from _________   show
🗑
show small, top  
🗑
Parvocellular layers are responsive to _________, _________, _________/_________ objects, and input primarily from cones   show
🗑
Retinotopic organization of primary visual cortex means that information received at _________ portions of the retina _________ _________ in the striate cortex   show
🗑
show contrast  
🗑
Mach bands are _________ striped that the visual system _________ for enhancement   show
🗑
Mach bands makes edges _________ to see, are a consequence of _________ _________   show
🗑
_________ _________ is the area of the visual field within which it is possible for a visual stimulus to influence the firing of a GIVEN neuron   show
🗑
show Curare-d a cat, placed extracellular electrode near a neuron, mapped the receptive field  
🗑
show similarities  
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Receptive fields of _________ area are smaller than those in the periphery   show
🗑
Neuron's receptive fields are _________ in shape, and are _________ (respond to a particular eye)   show
🗑
show excitatory, inhibitory  
🗑
show on, inhibition  
🗑
show fully illuminated  
🗑
show diffuse  
🗑
firing responds to _________ _________ between centers and peripheries of their visual fields   show
🗑
Many cells have receptive fields with a _________-_________ organization   show
🗑
on/off-center neurons have excitatory and inhibitory regions separated by a _________ _________   show
🗑
show do not have  
🗑
show edges/bars, monocular  
🗑
Complex striate cells respond best to _________ _________ of a particular orientation   show
🗑
Binocular complex striate cells - over half are _________, the other half display _________ _________   show
🗑
End-stopped extrastriate cells respond best to _________ _________ of a particular _________ and orientation   show
🗑
Simple striate cells have _________ receptive fields, with on and off regions that are _________ and _________ sensitive   show
🗑
show monocular, complex  
🗑
show previous stimuli  
🗑
Complex striate cells have _________ receptive fields than simple   show
🗑
show orientation, receptive field  
🗑
show moving lines, moving corners/angles  
🗑
show functional  
🗑
show Yes  
🗑
What is the trichromatic theory of colour   show
🗑
short spectral sensitivity   show
🗑
show green/yellow  
🗑
long spectral sensitivity   show
🗑
show two different classes of cells that encode colour, another to encode brightness  
🗑
show opponent-process theory  
🗑
show both - colour by cones operates according to componenet theory, while opponent processing is seen at all subsequent levels  
🗑
Colour constancy is the _________ of the same colour despite the change in _________   show
🗑
Retinex theory states that colour perception is based on the _________ of light of different wavelengths that a surface reflects   show
🗑
As visual information flows through hierarchy, receptive fields become _________ and respond to ...   show
🗑
Scotomas are areas of _________ in contralateral visual field due to damage to the _______ _________ cortex   show
🗑
show conscious awareness  
🗑
what is a possible explanation of blindsight?   show
🗑
Lesions in each area of the secondary visual cortex and association cortex result in _________ deficits   show
🗑
How many functionally distinct areas have been identified so far in the secondary visual and association cortexes?   show
🗑
show Dorsal and ventral streams  
🗑
The dorsal stream is the pathway from _________ to _________ to _________.   show
🗑
show where, control of behaviour  
🗑
Ventral stream is the pathway from the _________ to _________ to _________   show
🗑
show what, conscious perception of objects  
🗑
show visual agnosia, prosopagnosia, akinetopsia  
🗑
Visual agnosia is the inability to distinguish between   show
🗑
Prosopagnosia is the inability to distinguish   show
🗑
show movement in a normal, smooth fashion  
🗑


   

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