PSYC 271 Midterm 2
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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show | Ions
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show | Difference in the concentration of charges between two solutions
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show | electrostatic pressure
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4 important ions for neural conduction | show 🗑
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show | Voltmeter, or oscilloscope with electrical stimulator
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____ concentration is higher outside of the cell | show 🗑
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____ concentration is higher inside the cell | show 🗑
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Na is driven in by both ______ _______ and its _____ _____ (random motion) | show 🗑
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show | IN, OUT
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show | active force (ATP) that exchanges 3NA+ inside for 2K outsode
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EPSP causes ______, and an ______probability of action potential. Ie Na or Ca influx | show 🗑
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show | hyperpolarization, decreased
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PSPs are _______, and they are transmitted ______ and ______ | show 🗑
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show | less negative, closer, more
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show | more negative, further, less
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What is typically needed to cause a neuron to fire? | show 🗑
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In order to generate an AP, the ______ of _____ must be reached near the axon | show 🗑
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show | -65mV
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3 examples of spatial summation of PSPs | show 🗑
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Temporal summation of PSPs | show 🗑
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Steps in ionic basis of action potentials: | show 🗑
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Resting membrane potential: | show 🗑
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Depolarization | show 🗑
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show | point that voltage gated sodium channels open, AP occurs
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show | membrane potential becomes negative again, approaching the resting membrane potential
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Hyperpolarization: | show 🗑
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show | backward
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Absolute refractory period: | show 🗑
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show | Threshold less negative than rest, more difficult to initiate another AP (more depolarization necessary)
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show | active, slower, nondecremental
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Diffusion of Na+ triggers next ___ ____ | show 🗑
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show | Na
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show | to
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Antidromic conduction is transmission | show 🗑
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show | saltatory conduction
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show | Myelinated, larger
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show | squid, different, mammal cerebral
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Fo interneurons fire action potentials? | show 🗑
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Are dendrites able to fire action potentials? | show 🗑
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Mammal cerebral action potentials vary in ____, ______, and ______ | show 🗑
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Can mammalian cerebral axons fire potentials in the absence ofinput? | show 🗑
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Axoaxonic synapses | show 🗑
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show | bidirectional
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show | rare
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show | synapses between axon shafts - parallel side by side, synapse onto other
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show | common for monoamine neurotransmission - diffuse release of NT
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Some communication is through ____ _____ between cells | show 🗑
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_____ appear to modulate neuronal activity within their own domain | show 🗑
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show | cytoplasm of axon terminal buttons
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show | packaged into synaptic vesicles by golgi complex at terminal button
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show | in cytoplasm of cell body by ribosomes
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Packaging of large molecule neurotransmitter | show 🗑
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Transport of large molecule neurotransmitter | show 🗑
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show | small, large, each
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show | AP arrives at terminal button, voltage gated calcium channels open, Ca++ enters, vesicles fuse, empty contents via exocytosis
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Ionotropic receptors AKA ______ or _______ | show 🗑
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Ionotropic receptors are ____ acting | show 🗑
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Ionotropic receptirs usually have a _____ effect | show 🗑
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Depending on the type, Ionotropic receptros can _____ or _____ | show 🗑
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Metabotropic receptors AKA | show 🗑
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Metabotropic receptors are usually ____ acting | show 🗑
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Metabotropic receptors have a ____ effect by modifying ___ ____ | show 🗑
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show | neurotransmitter, neurotransmitter
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Neurotransmitter reuptake | show 🗑
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Neurotransmitter degradation by enzymes | show 🗑
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show | Amino acids, monoamines, acetylcholine, unconventional neurotransmitters, neuropeptides
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AA NTs | show 🗑
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show | more diffuse, non-directed synapses. Metabotropic receptors with diverse functions, arise in brainstem. Catecholamines, indolamines
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Ach NTs | show 🗑
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What defines something as an unconventional neurotransmitter? | show 🗑
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show | Soluble gases that exist only briefly, endocannabinoids
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Soluble gases that exist only briefly | show 🗑
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show | produced on-demand, released from dendrites, inhibit presynaptic neurons. rapidly degraded
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Neuropeptides are ____ ______ of amino acids | show 🗑
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show | variety
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show | Endorphins ie Endogenous opiods, analgesia/reward system
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show | Facilitate neurotransmitter's effects
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Antagonists | show 🗑
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Drugs may impact ___ _____ of the synaptic transmission pathway | show 🗑
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Agonist drug effect on synthesis | show 🗑
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show | Blocks synthesis of NT molecule
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Agonist drug on breakdown | show 🗑
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show | NT molecules leak from vesicles, destroyed by degrading enzymes
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Agonist drug on exocytosis | show 🗑
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Antagonist drug on exocytosis | show 🗑
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Agonist drug on inhibitory feedback | show 🗑
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Antagonist drug on inhibitory feedback | show 🗑
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show | binds to postsynaptic receptor, activates/increases effect on NT molecule
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show | receptor blocker, binds to postsynaptic receptors to block NT effect
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show | blocks deactivation of NT, blocking degradation or reuptake
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Antagonist drug on deactivation | show 🗑
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show | acetylcholine receptor subtypes, endogenous opioids, antipsychotic drugs
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Historically, we used to think that each NT had ___ kind of receptor | show 🗑
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Different _____ selective to specific _____ subtypes, exerting different effects despite involving the same NT | show 🗑
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show | Different locations, receptor function, and behavioural effects
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show | Activation at neuromuscular junction stimulates muscle contraction
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show | Activation slows heart and constricts pupils in ANS
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Ancient Greeks would consume _____ extracts for stomach ailments and pupil dilation | show 🗑
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The PNS releases ______ on _______ receptors within iris sphincter muscles to constrict pupils | show 🗑
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_____, the main active ingredient of belladonna, blocks _____ receptors, blocking Ach effect on pupils | show 🗑
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_______: Extract of certain vines used by South American natives as a paralytic poison for darts in hunting and war | show 🗑
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Curare blocks _____ receptors at the neuromuscular junction, causing _____ | show 🗑
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show | no muscular movement during surgery, but artificial respiration needed
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Extracted toxin of botulism bacteria | show 🗑
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show | acetylcholine, tremors, wrinkles
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show | brain mechanisms of pleasure and pain
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show | Opium
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Main active ingredient in Opium is _____, an analgesic | show 🗑
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show | PAG
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show | Analgesia
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show | Endorphins
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"in the head" opiates | show 🗑
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show | Parkinsonian-like
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Parkinson's disease associated with death of what? Where? | show 🗑
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______ _____, such as cocaine and amphetamines can induce and exacerbate phycosis | show 🗑
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Dopamine antagonists can _____ psychotic symptoms | show 🗑
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What are 2 X-ray based research techniques? | show 🗑
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show | PET and SPECT
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What are 3 magnetic field-based research techniques? | show 🗑
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show | Dense, softer
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Are X rays normally useful for neuroimaging? Why or why not? | show 🗑
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show | skull and bone fragments, foreign objects
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show | carcinogenic
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show | 2D
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show | radio-opaque, absorbs
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_____ ______ is excellent at imaging blood vessels | show 🗑
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show | multiple angles, 3D
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show | Relatively low
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Health effects of CT better or worse than X-ray? Why? | show 🗑
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show | local blood flow
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show | positrons
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Typical examples of radiolabelled tracers used in SPECT | show 🗑
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show | Intravenously
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SPECT has very _____ temporal resolution | show 🗑
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show | specific substances
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show | Alzheimers - decreased temporal-parietal metabolism
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PET has the same features as SPECT, except what? | show 🗑
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PET tracers have longer or shorter half lives than SPECT? | show 🗑
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show | 2-DG, taken up by active NTs (not metabolized) anywhere glucose is taken up
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Why is PET expensive | show 🗑
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PET tracers are usually administered ____ or ____ | show 🗑
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Pet has ____ spatial and temporal resolution than SPECT, but is more expensive | show 🗑
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Constructed image from measures electromagnatic signals emitted by H atoms as they return to alignment with a strong magnetic field after a radio-frequency burst | show 🗑
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MRI has very ____ resolution 3D images | show 🗑
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There is high ____ between white and gray matter in MRIs | show 🗑
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What can MRIs be combined with? Examples? | show 🗑
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Exceptions to MRI safety/non-invasiveness | show 🗑
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show | fMRI
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show | Cognitive activity
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what response does fMRI measure? | show 🗑
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What can fMRI be used to detect alongside BOLD? | show 🗑
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show | Paired-image subtraction/ controls for external thought, isolates for actual elucidated response
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show | Low frequency fluctuations, regional homegeneity
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Diffusion Tensor Imaging measures pathways along which ____ _____ rapidly diffuse | show 🗑
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show | connected
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fUS imaging | show 🗑
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show | blood volume
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show | passage
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show | cheap, prtable, useful for those who can't use PET or MRI
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show | lesions
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fMRI signals is a process that occurs many times/second, so signals can be _____ to one another | show 🗑
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The default mode network is _____ _____ throughout the brain | show 🗑
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What is the default mode network? | show 🗑
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Default mode network is a source of ____ ____, actively unrelated to a task | show 🗑
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show | near-infrared light
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fNIRS involves measuring changes in _____ and ____________ concentration | show 🗑
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Measures electical activity on the scalp and is a reflection of neuronal synchrony | show 🗑
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show | epilepsy, temporal, spatial
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EEG measures the ______ of brain waves | show 🗑
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show | Increasing the number of electrodes
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show | event-related potentials
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EEG _______ cancels out after a certain amount of trials | show 🗑
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Early EEG components are usually related to ______ features (exogenous components) | show 🗑
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show | cognitive
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show | Far Field Potentials
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show | Magnetoencephalography
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show | heavily insulated
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brain electrical currents create _____ _____ _____ | show 🗑
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show | coils
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Pros of MEG | show 🗑
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measures the changing difference in the voltage between two large electrodes placed on the skin above a large muscle | show 🗑
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What does EMG measure? | show 🗑
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What is electrooculagraphy (EOG)? | show 🗑
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EOG has been replaced by what? | show 🗑
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The general level of skin conductance associated with a particular situation | show 🗑
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A rapid change in skin conductance in response to a particular event | show 🗑
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Example of skin conductance response uses? | show 🗑
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show | Heart rate
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Blood pressure is measured via a | show 🗑
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show | Plethysmography
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show | decreases
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If behaviour from TMS is disrupted, that means what? | show 🗑
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Transcranial electrical stimulation _______ brain function by passing ____ _____ through the cortex | show 🗑
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In tES, is the current strong enough to elicit an action potential? | show 🗑
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How does transcranial direct current stimulation work? | show 🗑
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show | electrodes
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show | frequency, strength
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show | frequency
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tRNS has different effects depending on _____ of stimulation | show 🗑
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show | animal
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Stereotaxic surgery uses stereotaxic ______ and instrument | show 🗑
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show | lesions, probes, electrodes
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In a _______ lesion, tissue is sucked up into a pipette | show 🗑
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What remains behind following an aspiration lesion? why? | show 🗑
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________-________ lesions occur when high-frequency currents are administered through the tip of an electrode | show 🗑
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show | heat
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Radio frequency lesions everything where? | show 🗑
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Knife cut lesions are useful for _____ | show 🗑
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show | inactivate
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show | Lidocaine, cold
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Excitotoxic lesions excite neurons past the point of what? | show 🗑
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show | tracts and blood vessels
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show | more
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show | compensates for
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show | localization
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show | Unilateral, bilateral
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What kind of stimulation typically has the opposite effect of lesions? | show 🗑
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Intracellular unit recording measures changes in the ___ _____ of a neuron over time, requiring a ______ positioned inside a neuron | show 🗑
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show | Hard to keep microelectrode inside neuron
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show | near
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show | spikes, action potential
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show | amplitude
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show | rate of firing
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Invasive EEG uses electrodes where? | show 🗑
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show | more accurate recordings than normal (scalp) EEG
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The route of drug administration influences the ____ and _____ to which the drug reaches its site of action | show 🗑
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Difficulties of oral ingestion in non-human subjects? | show 🗑
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Absorption via the digestive tract is _________ | show 🗑
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show | capillaries
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show | regulation can be difficult, can damage lungs
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Absorption through mucous membrane entry points: | show 🗑
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show | digestive tract
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show | Intraperitoneally
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show | Subcutaneously
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show | Intramuscularly
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show | Intravenously
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______ injection is injection into CNS | show 🗑
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Central injection bypasses digestive tract and ____ ____ _____ | show 🗑
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Into a ventricle to affect the whole brain | show 🗑
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Autoradiography measures the location of _______ of interest when the brain is active during an _____ | show 🗑
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Difference between PET scan and autoradiography | show 🗑
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show | vivo
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show | antibodies
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show | mRNA/DNA
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Organisms lacking a ______ of interest | show 🗑
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Replacing one gene with another gene | show 🗑
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CRISPR/Cas9 edit genes at a particular time of ______- | show 🗑
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Optogenetics is the combination of _______ and _____ methods to achieve gain or loss of function in specific cells of living tissue | show 🗑
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Current neurophychological assessments focus more on the ______ of a patient | show 🗑
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Brain scanning is best at _____ _____ or metabolic disturbances, but lack ______ to other problems | show 🗑
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show | No
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What is a standard battery of neuropsychological tests? | show 🗑
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Problem with the standard battery of neurophychological tests? | show 🗑
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What is the HRB test? | show 🗑
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HRB Category Test | show 🗑
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show | placing varied shapes in holes without sight
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show | detect similarities and differences between rhythms
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HRB speech sounds perception test | show 🗑
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show | Tap index finger as fast as possible for 10 seconds
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show | tests visual attention and task switching
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show | Tests motor difficulties of each hemisphere
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Customized test batteries are used to measure ________, with more precise tests used in follow-ups | show 🗑
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show | modern theories
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Cognitive _____, not just performance is measured in customized test batteries | show 🗑
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3 tests of the common neuropsychological battery measure what? | show 🗑
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show | general verbal skills including verbal fluency, relies on prior knowledge
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show | examines a problem, drawing upon visual motor/spatial skills
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show | hold information so it can be used to solve a problem
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show | focus attention, quickly scan, discriminate between, and sequentially order visual information
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How do they measure which hemisphere is dominant for language? | show 🗑
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What is species common behaviours? | show 🗑
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What do the open field tests and the elevated plus maze test for | show 🗑
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What are the three measures of emotionality | show 🗑
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In the colony-intruder paradigm, rats are placed in a chamber with a _________,_________ rat | show 🗑
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show | lordosis
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How to measure sexual behaviour in male rats | show 🗑
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show | step-by-step process, temporal continuity, principle of equipotentiality
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show | spatial
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show | anti-anxiety
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show | sensitivity and acuity, iris
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The lens focuses light on the _________, in a process called _________ | show 🗑
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When the lens is cylindrical, focus is on a _________ object | show 🗑
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When the lens is flattened, focus is on a _________ object | show 🗑
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Most of what is seen is seen through _________ eyes | show 🗑
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show | closer, depth perception
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show | front
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show | side
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show | 5
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the fovea has high _________ vision | show 🗑
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optic disk involves the _________ spot and _________ | show 🗑
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show | no, some can see in very little light
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Wavelength is associated closely with the perception of | show 🗑
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intensity is closely associated with the perception of | show 🗑
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_________ is the turning of the eyes slightly inward when looking at something nearby | show 🗑
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In the retina, the cells at the _________ are the first to detect light | show 🗑
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show | inside-out
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show | cell
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show | five
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Receptor layer of the retina | show 🗑
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show | lateral communication
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amacrine cell later of retina | show 🗑
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show | high-acuity
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show | thinning, distortion
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the optic disk is where axons of _________ ganglion cells penetrate _________, exit eye through optic nerve | show 🗑
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show | different kinds of vision
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show | phototopic, high-acuity
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show | scototpic, high-sensitivity, detail
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show | low
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show | high
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show | cones
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show | neither
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show | spectral
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show | saccdes
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the visual system responds to _________ | show 🗑
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show | conversion
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show | light
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Visual transduction information is transmitted via | show 🗑
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What is the pigment found in rods? | show 🗑
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Rhodospin is a receptor that responds to _________ rather than NTs | show 🗑
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In the dark, rhodopsin Na+ channels are partially _________, (partial _________), _________ glutamate | show 🗑
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show | close, hyperpolarize, inhibiting
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In both eyes, left hits _________ and right hits _________ | show 🗑
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Each eye only processes _________ of visual field, contralaterally | show 🗑
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The _________ hemiretina of each eye connects to the _________ lateral geniculate nucleus, | show 🗑
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Magnocellular layers have _________ cell bodies, are the _________ 2 laters of LGN | show 🗑
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Magnocellular bodies are particularily responsive to _________, input primarily from _________ | show 🗑
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show | small, top
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Parvocellular layers are responsive to _________, _________, _________/_________ objects, and input primarily from cones | show 🗑
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Retinotopic organization of primary visual cortex means that information received at _________ portions of the retina _________ _________ in the striate cortex | show 🗑
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show | contrast
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Mach bands are _________ striped that the visual system _________ for enhancement | show 🗑
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Mach bands makes edges _________ to see, are a consequence of _________ _________ | show 🗑
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_________ _________ is the area of the visual field within which it is possible for a visual stimulus to influence the firing of a GIVEN neuron | show 🗑
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show | Curare-d a cat, placed extracellular electrode near a neuron, mapped the receptive field
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show | similarities
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Receptive fields of _________ area are smaller than those in the periphery | show 🗑
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Neuron's receptive fields are _________ in shape, and are _________ (respond to a particular eye) | show 🗑
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show | excitatory, inhibitory
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show | on, inhibition
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show | fully illuminated
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show | diffuse
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firing responds to _________ _________ between centers and peripheries of their visual fields | show 🗑
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Many cells have receptive fields with a _________-_________ organization | show 🗑
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on/off-center neurons have excitatory and inhibitory regions separated by a _________ _________ | show 🗑
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show | do not have
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|
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show | edges/bars, monocular
🗑
|
||||
Complex striate cells respond best to _________ _________ of a particular orientation | show 🗑
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||||
Binocular complex striate cells - over half are _________, the other half display _________ _________ | show 🗑
|
||||
End-stopped extrastriate cells respond best to _________ _________ of a particular _________ and orientation | show 🗑
|
||||
Simple striate cells have _________ receptive fields, with on and off regions that are _________ and _________ sensitive | show 🗑
|
||||
show | monocular, complex
🗑
|
||||
show | previous stimuli
🗑
|
||||
Complex striate cells have _________ receptive fields than simple | show 🗑
|
||||
show | orientation, receptive field
🗑
|
||||
show | moving lines, moving corners/angles
🗑
|
||||
show | functional
🗑
|
||||
show | Yes
🗑
|
||||
What is the trichromatic theory of colour | show 🗑
|
||||
short spectral sensitivity | show 🗑
|
||||
show | green/yellow
🗑
|
||||
long spectral sensitivity | show 🗑
|
||||
show | two different classes of cells that encode colour, another to encode brightness
🗑
|
||||
show | opponent-process theory
🗑
|
||||
show | both - colour by cones operates according to componenet theory, while opponent processing is seen at all subsequent levels
🗑
|
||||
Colour constancy is the _________ of the same colour despite the change in _________ | show 🗑
|
||||
Retinex theory states that colour perception is based on the _________ of light of different wavelengths that a surface reflects | show 🗑
|
||||
As visual information flows through hierarchy, receptive fields become _________ and respond to ... | show 🗑
|
||||
Scotomas are areas of _________ in contralateral visual field due to damage to the _______ _________ cortex | show 🗑
|
||||
show | conscious awareness
🗑
|
||||
what is a possible explanation of blindsight? | show 🗑
|
||||
Lesions in each area of the secondary visual cortex and association cortex result in _________ deficits | show 🗑
|
||||
How many functionally distinct areas have been identified so far in the secondary visual and association cortexes? | show 🗑
|
||||
show | Dorsal and ventral streams
🗑
|
||||
The dorsal stream is the pathway from _________ to _________ to _________. | show 🗑
|
||||
show | where, control of behaviour
🗑
|
||||
Ventral stream is the pathway from the _________ to _________ to _________ | show 🗑
|
||||
show | what, conscious perception of objects
🗑
|
||||
show | visual agnosia, prosopagnosia, akinetopsia
🗑
|
||||
Visual agnosia is the inability to distinguish between | show 🗑
|
||||
Prosopagnosia is the inability to distinguish | show 🗑
|
||||
show | movement in a normal, smooth fashion
🗑
|
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Or sort by any of the columns using the down arrow next to any column heading.
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Created by:
esavoy