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Phase 1 week 5 PBL

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show Cartilage is a CONNECTIVE TISSUE consisting of a dense matrix of collagen fibres and elastic fibres embedded in a rubbery ground substance. Is strong and flexible.  
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What are the main cells in cartilage?   show
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show Chondrocytes = mesenchymal stem cells - they synthesise and maintain EM  
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show It cushions bones at joints  
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show In most species it is converted largely to bone with maturation  
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show Forms most of the TEMPORARY SKELETON of the embryo. • During the embryonic development of most vertebrates, the skeleton forms as cartilage before most of it hardens to bone  
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List the three different types of cartilage and give where they are found   show
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show Cartilage is NOT INNERVATED (supplied with nerves) and therefore relies on diffusion to obtain nutrients. This causes it to heal VERY SLOWLY.  
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show . Cartilage differs from bone in that it is AVASCULAR and its microarchitecture is less organised than bone. Cartilage is NOT INNERVATED (supplied with nerves) and therefore relies on diffusion to obtain nutrients. This causes it to heal VERY SLOWLY.  
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What is the matrix in cartilage produced by and what happens to them?   show
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show MATURE CARTILAGE CELLS = CHONDROCYTES  
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show They occur, either singly or in groups, within spaces called LACUNAE (singular, lacuna) in the matrix  
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show The surface of most of the cartilage in the body is surrounded by a membrane of dense irregular connective tissue called PERICHONDRIUM  
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show Unlike other connective tissues, cartilage contains NO BLOOD VESSELS OR NERVES - EXCEPT in the perichondrium  
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show • Few visible collagen fibres (in light microscope) • Avascular • Has perichondrium, except for articular cartilage  
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What does hyaline cartilage cover and where especially?   show
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show Hyaline cartilage  
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What is the matrix of hyaline cartilage mostly made up of?   show
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show Hyaline cartilage tissue provides SMOOTH SURFACES, enabling tissues to move/slide easily over each other, e.g. facilitating smooth movements at joints. It also provides flexibility and support  
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What is fibrocartilage?   show
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show A perichondrium  
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show • Avascular • Abundant collagen fibres • Chondrocytes aligned  
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What is special about fibrocartilage?   show
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Give three places where fibrocartilage tissue is found   show
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show Fibrocartilage  
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Give three places where elastic cartilage is found   show
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show Function is to provide support and maintain shape  
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show Yes, and hyaline cartilage - it is just fibrocartilage that doesn't have a perichondrium  
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show In elastic cartilage, which is yellowish in colour, the cartilage cells (chondrocytes) are located in a threadlike network of elastic fibres within the matrix of the cartilage  
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What do the elastic fibres in elastic cartilage look like under the microscope? What lies between the fibres in elastic cartilage?   show
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What is the principal protein in elastic cartilage?   show
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show It's a STRUCTURAL PROTEIN arranged as fibres -Abundant in skin, lung and blood vessels - stretch and elastic recoil -Assembly into functional fibres requires the presence of a structural glycoprotein - FIBRILLIN  
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Created by: Aimee76