Modulation of movement by the cerebellum
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show | False. They send prominant projections to virtually all circuits that govern Upper motor neurons
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Projections TO the cerebellum come from the | show 🗑
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show | the deep cerebellar nuclei
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show | To detect the difference or "motor error" between the intended movement and the actual movment
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show | Purkinje cells are GABAergic. They are the only source of output from the cerebellum
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show | Axons from the pontine nuclei are called mossy fibers.
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Where do mossy fibers receive their projections from? | show 🗑
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show | The contralateral cerabellar cortex. They synapse on neurons in the deep cerebellar nuclei, and on granule cells in the granule layer of the cererbal cortex.
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What are the axons of granule cells called, and where do they go? | show 🗑
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show | They form T-shaped excitatory synapses with the dendrites of Purkinje cells.
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True or false: Mossy fibers from the pontine nuclei synapse with granule cells, whose axons (parallel fibers) synapse with purkinje cells | show 🗑
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True or false: Parallel fibers are the same thing as purkinje cells. | show 🗑
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show | Climbing fibers are the axons of the cells arising from the inferior olive.
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show | Climbing fibers directly modulate input to purkinje cells
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True or false: The Sole output of the cerebellum is excitatory | show 🗑
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show | They are found in the molecular layer. They receive input from parallel fibers, and provide inhibitory feedback to granule cells.
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show | LTD happens when both climbing fibers and parallel fibers are activated at the synapses with Purkinje cells.
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show | There is a reduction in the efficacy of parallel fiber input to purkinje cells. This weakens the influence of the inhibitory loop by increasing the response of neurons in the deep cerebellar nuclei to afferent activity
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What does the formation of LTD seem to be? | show 🗑
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show | Reductions in the purkinje cell responses to parallel fiber inputs.
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