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chapter 23

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What name is given to the intermediate in an enzyme-catalyzed reaction?   Enzyme-substrate complete  
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Which of the following will cause the rate of enzyme activity to first increase and then level off?   increasing the substrate concentration.  
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Which of the following is the reason that trypsin is synthesized as trypsinogen?   trypsin would attack the body's natural proteins.  
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Which of the following is associated with noncompetitive inhibition?   allosterism  
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In which type of inhibition is it not possible to restore the maximum rate of enzyme activity by adding additional substrate?   noncompetitive inhibition  
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Which of the following is true?   the majority of enzymes are globular proteins.  
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In which type of inhibition is it possible to restore the maximum rate of enzyme activity by adding additional substrate?   Competitive inhibition.  
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Which of the following is true of enzymes?   both a and b, (think about what an enzyme does and what it is.)  
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What is the general name used when the product of a reaction sequence inhibits an earlier step in that sequence?   Feedback control  
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In Which type of inhibition does the inhibitor bind to the active site?   Competitive inhibition.  
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The names of enzymes are often derived from which of the following?   both a and b, (~where they catalyze an what they catalyze?)  
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Which of the following will cause the rate of enzyme activity to increase linearly?   increasing the enzyme concentration  
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Which of the following is commonly associated with protein modification?   Phosphorylation/dephosphorylation  
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Which of the following is true of all allosteric enzymes?   Binding at one site affects protein function at a second site.  
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Transition- state analogs do which of the following ?   all of the above,(mimics transition state of substrate experimentally used to verify active site clinically inhibit enzymes used to design artificial enzymes.)  
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Which of the following is true of isozymes?   They are different forms of the same enzyme found in different tissues.  
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Which of the following can cause enzyme activity to either increase or decrease?   both a and b,(ph and temp?.)  
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What term is used to describe a species which affects the functioning of an allosteric enzyme?   regulator  
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Which of the following is used in diagnosing infectious hepatitis?   ALT (Alanine aminotransferase .)  
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which of the following explains why succinylcholine is used as a muscle relaxant?   it is slowly hydrolyzed by acetylcholinesterase  
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Which of the following is another name for a proenzyme?   Zymogen  
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Which of the following are monitored to diagnose the severity of a heart attack?   All of these. (AST,LDH,CPK,PHI)  
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What name is given to any (organic or inorganic) nonprotein portion of an enzyme?   cofactor  
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What name is given to the molecule on which the enzyme works?   substrate  
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In addition to proteins, which type of molecules sometimes function as enzymes?   RNA  
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Which of the following is a foreign substance that produces an immune response?   An antigen  
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In which type of inhibition does the inhibitor bind to the protein at a site other than the active site?   noncompetitive inhibition  
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What disease is diagnosed by monitoring amylase activity?   pancreatic disease  
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What disease is diagnosed by monitoring acid phosphatase activity?   prostate cancer  
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An abzyme is which of the following?   An antibody with catalytic ability  
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What is the name given to a material which slows down enzyme function?   Inhibitor  
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What name is given to the organic cofactor of an enzyme?   coenzyme  
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