| |
| Which of the following diseases is generally caused by contaminated food?
Mumps
Shigellosis
Legionellosis
Tuberculosis | Shigellosis |
| “Animalcules” were first described by
Robert Hooke
Antonie van Leeuwenhoek
Hans Janssen
John Needham | Antonie van Leeuwenhoek |
| A microscope that provides a three-dimensional image of a specimen is a
dark-field microscope.
transmission electron microscope.
bright-field microscope.
scanning electron microscope. | scanning electron microscope. |
| Which of the following scientists discovered the antibiotic properties of Penicillium?
Alexander Fleming
Louis Pasteur
Joseph Lister
Edward Jenner | Alexander Fleming |
| Which scientist is most responsible for ending the controversy about spontaneous generation?
John Needham
Joseph Lister
Louis Pasteur
Robert Koch | Louis Pasteur |
| Molds belong to which of the following groups of eukaryotic organisms?
Protozoans
Archaea
Fungi
Algae | Fungi |
| Which of the following is used to add color to microbes so they can be better observed under a microscope?
Stains and dyes
Growth media
Inoculation loops
Petri dishes | Stains and dyes |
| Complex communities of microorganisms on surfaces are called
colonies
biofilms
biospheres
flora | biofilms |
| A relationship between organisms in which the waste product of one provides nutrients for another is called
mutualism
competition
synergism
commensalism | commensalism |
| Which of the following scientists performed the first vaccination against smallpox?
Pasteur
Jenner
Semmelweis
Koch | Jenner |
| The cell organelles found only in algae and plant cells are
chloroplasts
mitochondria
vacuoles
vesicles | chloroplasts |
| The structures that can move fluid, mucus, or cells over the surface of a cell are
microvilli
cilia
fimbriae
flagella | cilia |
| The cell organelle responsible for the packaging of proteins is the
ribosome
Golgi complex
rER
lysosome | Golgi complex |
| Which of the following organelles contain oxidative enzymes capable of oxidizing toxic substances?
Mitochondria
Chloroplasts
Lysosomes
Peroxisomes | Peroxisomes |
| Which of the following organisms produces toxins that target cholesterol?
Aeromonas hydrophila
Escherichia coli
Streptococcus pyogenes
Corynebacterium diphtheriae | Streptococcus pyogenes |
| Which of the following is an active transport mechanism?
Osmosis
Facilitated diffusion
Filtration
Pinocytosis | Pinocytosis |
| Binary fission is a form of reproduction used by
viruses
bacteria
fungi
helminths | bacteria |
| he actual genetic makeup of an organism is referred to as its
phenotype
genotype
conjugation
construct | genotype |
| A special structure formed by some bacterial cells to allow them to survive in harsh conditions is called a(n)________________________.
Nuclein
Mitochondria
Endospore
Cytoplasm | Endospore |
| Formic acid is a fermentation product of
Streptococcus
Klebsiella
Clostridium
Actinomyces | Actinomyces |
| Rod-shaped bacteria, some of which are endospore forming, are referred to as
cocci
bacilli
spirals
vibrios | bacilli |
| Beadlike chains of cocci formed after cell division along a single axis are called
diplococci
streptococci
tetrads
sarcinae | streptococci |
| The causative agent for Lyme disease is a
Spirochete
Spirillum
Vibrio
Diplococcus | Spirochete |
| Bacteria that use organic compounds as the source of both carbon and energy are referred to as
photoautotrophs
chemoautotrophs
photoheterotrophs
chemoheterotrophs | chemoheterotrophs |
| Microorganisms that show optimal growth in moderate temperatures (between 25° C and 40° C) are called
thermophiles
psychrophiles
mesophiles
psychrotrophs | mesophiles |
| Which of the following organisms is a common cause of peptic ulcers?
Treponema pallidum
Vibrio cholerae
Helicobacter pylor
Escherichia coli | Helicobacter pylor |
| Legionella and Neisseria are examples of
facultative anaerobic gram-negative rods
gram-negative aerobic rods and cocc
spirochetes
anaerobic gram-negative cocci | gram-negative aerobic rods and cocc |
| Staphylococci and streptococci are best classified in the group of
gram-positive cocci
gram-negative cocci
gram-negative aerobic rods and cocci
anaerobic gram-negative cocci | gram-positive cocci |
| Bacteria that prefer high levels of salt in their growing environment are referred to as
calciphiles
halophiles
osmophiles
mesophiles | halophiles |
| The time bacteria need to adapt to a medium before cell division starts is called the __________ phase of a bacterial growth curve.
Lag
Logarithmic growth
Stationary
Death | Lag |
| Viruses can infect
plants
bacteria
animals
all organisms | all organisms |
| adsorption, penetration, uncoating, replication, assembly, release
penetration, adsorption, assembly, uncoating, replication, release
adsorpb, uncoat, penetrate, replicate, assembly, release
penetrate, uncoat, adsorpb, replicate, assembly, release | adsorption, penetration, uncoating, replication, assembly, release |
| A persistent infection that is not lytic but productive is called a __________ infection.
chronic
latent
slow
transforming | chronic |
| Which of the following viruses belong to the family Herpesviridae?
Poxvirus
Epstein-Barr virus
SARS
HIV | Epstein-Barr virus |
| The most common viruses causing respiratory illness belong to
Herpesviridae
Papovaviridae
Adenoviridae
Poxviridae | Adenoviridae |
| Which of the following bunyaviruses is not arthropod-borne?
Phlebovirus
Hantavirus
Nairovirus
Uukuvirus | Hantavirus |
| Which of the following diseases is caused by a human coronavirus?
Hepatitis B
Measles
SARS
Creutzfeldt-Jacob Disease | SARS |
| Transmissible spongiform encephalopathies are caused by
You Answered
flavoviruses
virusoids
prions
orthomyxoviruses | prions |
| The phase of viral multiplication where no infectious phage particles can be found in the host cell is referred to as the ____________ period.
Lytic
Eclipse
Lysis and release
Lysogenic | Eclipse |
| A virus that infects bacteria is referred to as a __________
virusoid
bacteriophage
viroid
prion | bacteriophage |
| The antibiotics penicillin and cephalosporin are produced by
algae
slime molds
fungi
protozoans | fungi |
| Fungi are free-living _________ organisms.
autotrophic
chemotrophic
heterotrophic
phototrophic | heterotrophic |
| The so-called “red tide” is generally caused by which of the following organisms?
Lichens
Bacteria
Pfiesteria
Dinoflagellates | Dinoflagellates |
| Which of the following microorganisms require a moist environment to survive and most often live in ponds, streams, lakes, and oceans?
Mycorrhizae
Armillaria gallica
Blastospores
Protozoans | Protozoans |
| Plasmodium is a type of
algae
protozoan
slime mold
helminth | protozoan |
| Toxoplasma gondii belongs to which group of eukaryotic organisms?
Algae
Fungi
Protozoans
Helminths | Protozoans |
| Which of the following is commonly referred to as a pinworm?
Enterobius vermicularis
Necator americanus
Ascaris lumbricoides
Ancylostoma duodenale | Enterobius vermicularis |
| The protozoan that lacks a cyst stage and therefore must be transferred quickly from host to host is
Giardia lamblia
Trichomonas vaginalis
Balantidium coli
Entamoeba histolytica | Trichomonas vaginalis |
| The process by which the nucleus of protozoans undergoes multiple divisions before the cell divides is called
budding
mitosis
schizogony
fragmentation | schizogony |
| Many species of protozoans are capable of entering a dormant stage in which the organism exists as a __________
cyst
Mitosome
Apical complex
Sporozoite | cyst |
| Decontamination is defined as the
killing of all microorganisms in a given area
reduction or removal of unwanted chemical or biological agents
stopping of the growth of microorganisms in a given area
removal of all vegetative organisms | reduction or removal of unwanted chemical or biological agents |
| Which of the following has a higher resistance to environmental stresses than the others?
Bacterial endospores
Fungal spores
Enveloped viruses
Vegetative bacterial cells | Bacterial endospores |
| Which of the following methods is the simplest heat-related method to sterilize metal?
Incineration
Autoclaving
Direct flaming
Indirect heating | Direct flaming |
| The technique that combines freezing and drying to preserve microbes and other cells is
desiccation
lyophilization
pasteurization
radiation | lyophilization |
| The term “zone of inhibition” is used in which of the following procedures?
Use-dilution test
Growth inhibition test
Disk-diffusion test
Multiple inhibition test | Disk-diffusion test |
| Which of the following is a general-purpose medium?
Tryptic soy agar
Blood agar
Mannitol salt agar
MacConkey agar | Tryptic soy agar |
| The destruction of all microorganisms and their endospores is referred to as
disinfection
degermination
sanitization
sterilization | sterilization |
| Which of the following stains is the most widely used differential stain in hematology laboratories?
Carbolfuchsin stain
Ziehl-Neelson stain
Kinyoun stain
Wright’s stain | Wright’s stain |
| Media that contain complex organic substances such as blood for the growth of specific bacteria are referred to as
enriched media
general-purpose media
Irradiation
reducing media | enriched media |
| The stain used to identify bacteria with a large amount of peptidoglycan in their cell walls is the
acid-fast stain
methylene blue stain
Gram stain
negative stain | Gram stain |
| The branch of pharmacology that addresses drug amounts at various sites in the body after drug administration is called
pharmacodynamics
pharmacokinetics
pharmacotherapeutics
pharmacy | pharmacokinetics |
| The most rapid rate of drug absorption is achieved by __________ administration.
on the skin
intravenous
intramuscular
sublingual | intravenous |
| The specific antidote to botulinum toxin is
sodium bicarbonate
pralidoxime
antitoxin
naloxone | antitoxin |
| The term used to indicate the extent to which a drug reaches its site of action is
bioavailability
bioactivity
bioremediation
biostasis | bioavailability |
| All of the following are general metabolic or structural targets for antimicrobial drugs except
Lipid synthesis inhibition
Protein synthesis inhibition
Interference with nucleic acid synthesis
Interference with cell wall synthesis | Lipid synthesis inhibition |
| Which of the following is not a common characteristic used in the selection of an antimicrobial drug?
Selective toxicity
Ability to administer intravenously
Potential for allergic reaction | Ability to administer intravenously |
| The term bacteriostatic means that bacteria
are killed by the antimicrobial drug
show continuous growth
no longer cause disease
no longer can multiply | no longer can multiply |
| When two antibiotics are given together to increase the therapeutic effect, the phenomenon is referred to as
antagonism
mutualism
synergism
parasitism | synergism |
| Which of the following antimicrobials is effective against mycobacteria?
Penicillin
Rifampin
Erythromycin
Cephalosporin | Rifampin |
| Which of the following is an antiviral agent?
Amantadine
Vancomycin
Chloramphenicol
Macrolides | Amantadine |
| Which type of symbiosis benefits both members?
Mutualism
Parasitism
Commensalism
Pathogenesis | Mutualism |
| The presence of microbes in or on the body is a(n)
infection
disease
contamination
adhesion | contamination |
| When a pathogen spreads from the original site to other tissues or organs it is called a(n) __________ infection.
local
focal
natural
acute | focal |
| Which of the following is likely to be the most frequently used portal of entry for pathogens?
Skin
Gastrointestinal tract
Respiratory tract
Conjunctiva | Respiratory tract |
| The number of new cases of a disease over a certain period of time compared with the general healthy population is a referred to as
incidence
prevalence
virulence
mortality | incidence |
| An antibody is
a substance initiating an allergic response
a marker on the cell surface of macrophages
a protein produced by plasma cells
a marker on the cell surface of macrophages | a protein produced by plasma cells |
| Which of the following provide defense against viral infections?
Histamines
Antibiotics
Prostaglandins
Interferons | Interferons |
| Immunity that is a result of an actual infection is called
artificially acquired passive immunity
artificially acquired active immunity
naturally acquired passive immunity
naturally acquired active immunity | naturally acquired active immunity |
| Which of the following is not part of the second line of defense?
pH of the skin
Cytokines
Phagocytosis
Fever | pH of the skin |
| GALT is an example of a collection of lymphatic nodules in the
respiratory tract
small intestine
stomach
female reproductive system | small intestine |
| Langerhans cells, which play a role in defense against microbes, are located in the
Dermis
Mucous Membrane
Epidermis
Hypodermis | Epidermis |
| Which of the following organisms is the causative agent of skin infections and toxic shock syndrome?
Propionibacterium acnes
Micrococcus luteus
Staphylococcus aureus
Pseudomonas aeruginosa | Staphylococcus aureus |
| he organism often called “flesh-eating bacteria” is
Staphylococcus aureus
Streptococcus pyogenes
Propionibacterium acnes
Staphylococcus epidermidis | Streptococcus pyogenes |
| Warts are commonly caused by the
HIV
varicella-zoster virus
herpesvirus
human papillomavirus | human papillomavirus |
| Diaper rash in infants is commonly caused by
Actinomyces
Sporothrix schenckii
Malassezia furfur
Candida albicans | Candida albicans |
| Tinea capitis is a fungal infection of the
mouth
scalp
hands
feet | scalp |
| The most important fungi that cause diseases of the skin, hair, and nails are called
Plasmodium
sporozoites
dermatophytes
nematodes | dermatophytes |
| Its difficult for antibiotics to reach the infection site of osteomyelitis primarily because of
inflammation and edema
destruction of the local blood supply
denaturing of the drug by normal flora
excessive production of pus at the infection site | destruction of the local blood supply |
| Athlete’s foot” is referred to as
tinea pedis
tinea capitis
tinea versicolor
tinea corporis | tinea pedis |
| The papillary layer of the skin is part of the
dermis
hypodermis
subcutaneous layer
epidermis | dermis |
| All of the following are structures of the lower respiratory system except
Trachea
Pharynx
Lungs
Bronchi | Pharynx |
| Which of the following organisms is commonly found in the normal flora of the upper respiratory system?
Mycoplasma pneumoniae
Staphylococcus aureus
Klebsiella pneumoniae
Bordetella pertussis | Staphylococcus aureus |
| Whooping cough is caused by the organism
Corynebacterium diphtheriae
Bordetella pertussis
Haemophilus influenzae
Streptococcus pneumoniae | Bordetella pertussis |
| Tuberculosis is transmitted primarily through
aerosols
oral-fecal route
fomites
blood transfusions | aerosols |
| Which of the following geographic areas contains reservoirs for Coccidioides immitis?
France
Arizona
Iowa
South Africa | Arizona |
| The “strawberry tongue” symptom is often associated with
pharyngitis
pneumonia
scarlet fever
rheumatic fever | scarlet fever |
| Strep throat is caused by which of the following organisms?
Streptococcus agalactiae
Streptococcus faecalis
Streptococcus pyogenes
Streptococcus pneumoniae | Streptococcus pyogenes |
| Klebsiella pneumoniae is a
gram-negative, motile bacillus
gram-positive, spore-forming bacillus
gram-negative, encapsulated bacillus
gram-positive, encapsulated coccus | gram-negative, encapsulated bacillus |
| The formation of a “fungus ball” within preexisting cavities is a common development in
pulmonary aspergillosis
blastomycosis
histoplasmosis
coccidioidomycosis | pulmonary aspergillosis |
| Which of the following cannot be and should not be treated with antibiotics?
Diphtheria
Common cold
Strep throat
Tuberculosis | Common cold |
| All of the following are components of the gastrointestinal tract except the
stomach
spleen
pharynx
esophagus | spleen |
| Many peptic ulcers are due to
Helicobacter pylori
Salmonella enterica
Salmonella typhi
Shigella boydii | Helicobacter pylori |
| Bacillary dysentery is also called
campylobacteriosis
typhoid fever
shigellosis
salmonellosis | shigellosis |
| The most common cause of infectious diarrhea in infants and children is
adenoviruses
noroviruses
caliciviruses
rotaviruses | rotaviruses |
| (+) ssRNA viruses that have been isolated from birds, cats, dogs, pigs, sheep, cows, and humans and are a major cause of gastroenteritis are the
noroviruses
rotaviruses
adenoviruses
caliciviruses | caliciviruses |
| The human pinworm Enterobius vermicularis lives in the __________ of humans.
rectum
transverse colon
ileum | rectum |
| Giardiasis is a waterborne gastrointestinal disease caused by Giardia intestinalis, which is a
fungus
virus
protozoan
bacterium | protozoan |
| Cholera is a serious gastrointestinal illness caused by bacteria of the genus
Escherichia
Acinetobacter
Vibrio
Salmonella | Vibrio |
| Botulism is a disease caused by the production of a potent neurotoxin by bacteria of the genus
Salmonella
Klebsiella
Staphylococcus
Clostridium | Clostridium |
| A microbial biofilm that can form on the enamel surface of teeth and often causes tooth decay and/or periodontal problems is referred to as______ __________.
dental plaque
mucosa
periodontitis
gingivitis | dental plaque |
| An inflammation of the brain is called_________
meningoencephalitis
meningitis
bacteremia
encephalitis | encephalitis |
| To prevent meningitis, routine vaccination in the United States is provided against______________
Mycobacterium tuberculosis
Haemophilus influenzae
Neisseria meningitidis
Listeria monocytogenes | Haemophilus influenzae |
| Meningococcal meningitis is caused by________
Neisseria meningitidis
Listeria monocytogenes
Mycobacterium tuberculosis
Haemophilus influenzae | Neisseria meningitidis |
| In bacterial meningitis, some antibiotics are prevented from reaching the infection due to
chemical degradation of the antibiotic
scar tissue formation
degradation of local blood vessels
blood-brain barrier | blood-brain barrier |
| Toxoplasmosis is caused by the organism Toxoplasma gondii, which is a___________
virus
protozoan
fungus
bacterium | protozoan |
| The toxic condition caused by the multiplication of bacteria in the blood is referred to as_____
bloodborne infection
septicemia
shock
bacteremia | septicemia |
| When microorganisms enter the circulatory system through the lymphatic drainage and cause an infection, the condition is called__________________
viremia
microbemia
bacteremia
septicemia | microbemia |
| Malaria is caused by a _________
virus
helminth
protozoan
bacterium | protozoan |
| Which of the following is the causative agent for fungal meningitis, mostly in immunocompromised patients?
Trypanosoma cruzi
Trypanosoma brucei
Cryptococcus neoformans
Listeria meningitis | Cryptococcus neoformans |
| The term used to describe an inflammation of the saclike membrane surrounding the heart is ________________
anemia
myocardial infarction
pericarditis
peritonitis | pericarditis |
| The primary bacterium responsible for most UTIs is _______
Escherichia coli
Bacillus subtilis
Staphylococcus aureus
Lactobacillus acidophilus | Escherichia coli |
| The urinary tract infection involving infection of the urinary bladder is called __________
cystitis
colitis
phenylketonuria
gram-negativetoxoplasmosis | cystitis |
| The presence of bacteria in the urine is called
urethritis
bacteriuria
toxemia
mycoses | bacteriuria |
| The most common fungus causing urinary tract infections is
Microsporum
Candida albicans
Saccharomyces cerevisia
Rhizopus | Candida albicans |
| Two parasites that cause urinary tract infections are
Giardia lamblia and Treponema pallidum
Schistosoma haematobium and Trichomonas vaginalis
Plasmodium falciparum and Giardia lamblia
Plasmodium and Borrelia burgdorferi | Schistosoma haematobium and Trichomonas vaginalis |
| Bacteria responsible for nonsexually transmitted infections of reproductive system
S. faecalis, K. oxytoca, and S. marcescens
C. tetani, B. cereus, and S. aureus
N. gonorrhoeae, H. pylori, and P. aeruginosa
E. coli, G. vaginalis, and S. aureus | Escherichia coli, Gardnerella vaginalis, and Staphylococcus aureus |
| The normal flora present in the healthy male reproductive system is best characterized as
primarily gram-positive rods
sterile, no normal flora
acid-fast rods.
gram-positive spore formers only | sterile, no normal flora |
| Factors that can increase the chances of vaginitis are
use of antibiotics, pregnancy, and menopause
menopause, stress, and steroid use
puberty, exposure to HPV, and smoking/tobacco use
urinary blockage, drug use, and stress | use of antibiotics, pregnancy, and menopause |
| The drug most often used in fighting protozoan infections of the reproductive system is
ciprofloxacin
ampicillin
tetracycline
metronidazole | metronidazole |
| One of the defense mechanisms in place in the organs/tissues of the reproductive tract that prevent microbial infection includes
high sugar concentration
high body temperature
alkaline pH
acidic pH | acidic pH |
| The highly specialized structure that protects the fetus from microorganisms is the____________
mammary gland
uterus
placenta
vagina | placenta |
| Congenital CMV infections are caused by
coronavirus
Epstein-Barr virus
herpes simplex virus
cytomegalovirus | cytomegalovirus |
| Infectious mononucleosis most often occurs in
young adults
adolescents
the elderly
infants | young adults |
| Infectious diseases in the adult population are responsible for about one-third of all deaths in individuals over the age of
65 years
60 years
50 years
55 years | 65 years |
| Which of the following is a Category A agent?
Chlamydia psittaci
Vibrio cholerae
Bacillus anthracis
Escherichia coli | Bacillus anthracis |
| The most lethal form of anthrax is
nasopharyngeal
inhalation anthrax
gastrointestinal
cutaneous anthrax | inhalation anthrax |
| Which of the following diseases was declared by the WHO in 1980 to be eradicated?
Pertussis
Botulism
Mumps
Smallpox | Smallpox |
| Specific small niches in which populations and guilds within a community reside are referred to as ______
biospheres
habitats
ecosystems
microhabitats | microhabitats |
| Which of the following processes is most commonly used in wastewater treatment?
Carbon dioxide
Anammox
Sulfur
Phosphorus | Anammox |
| Which of the following diseases was declared by the WHO in 1980 to be eradicated?
Botulism
Pertussis
Mumps
Smallpox | Smallpox |