| Question | Answer |
| Cytokines that affect hematopoiesis in bone marrow are called colony-stimulating factors (CSFs)
based on their ability to: | Regulate blood cells |
| Which of the following genes for the hematopoietic growth factors has been cloned and its
recombinant protein is now used to treat anemia of kidney failure and cancer? | Epogen (EPO) |
| Leukocytes consist of three categories of cells that have different roles in the inflammatory and
immune responses. Which of the following leukocytes is correctly matched with its function? | Eosinophils—allergic reactions |
| A client asks, “What do these basophils and mast cells do in the body?” The health care provider
responds that they: | Are involved when you have an allergic reaction |
| T-cell lymphocytes leave the bone marrow and travel to the thymus. If successful, they
differentiate into which of the following cells? Select all that apply. | CD4+helper T cells
CD8+ cytotoxic T cells |
| A client with a long-standing diagnosis of human immunodeficiency virus (HIV) has recently
developed neutropenia and been admitted to a hospital. Which of the following measures should
be prioritized by the nurses who are providing his care? | Vigilant handwashing to protect against severe bacterial infections |
| Which of the following clients experiencing an abnormally low neutrophil count (neutropenia)
could have developed this as a side effect to his or her medical regimen? A client with: | Hyperthyroidism being treated with propylthiouracil to maintain normal metabolic rate |
| enlarged lymph nodes and a sore throat. His girlfriend was recently
diagnosed with infectious mononucleosis. While educating this teenager, the nurse emphasizes
that infectious mononucleosis is caused by which pathogen and usually transmitted via: | Epstein-Barr virus; saliva |
| daughter's recent malaise and lethargy. Which of the following assessments should the clinician
perform in an effort to confirm or rule out infectious mononucleosis? | Palpating the client's lymph nodes |
| Leukemias are classified according to the predominant cell type. The myelogenous cell type of
leukemia can: | Interfere with thrombocyte cell maturation |
| Which of the following clients are at high risk for developing acute myeloid leukemia? Select all
that apply. | Owner of a convenience store who pumps gas for his customers
C) Wife married to a “chain” smoker who smokes 3 packs/day for the past 50 years |
| A client presents to the emergency clinic not feeling well. Which of the following complaints
leads the health care provider to suspect the client may have acute leukemia? | Bleeding from the gums, not related to brushing the teeth |
| A client asks the health care worker why he is taking allopurinol. The client states, “I don't have
gout. My grandpa took this for his gout.” The best response would be: | “When the chemo kills the leukemia cells, this causes your uric acid levels to rise.
Allopurinol will help lower uric acid levels.” |
| Which of the following factors differentiates chronic leukemias from acute leukemias? | The leukemic cells are more fully differentiated than in acute leukemias. |
| An elderly client presents to the clinic just not “feeling well.” Which of the following bone
marrow results would confirm the diagnosis of chronic lymphocytic leukemia? | Proliferation of well-differentiated blood cells in the marrow |
| Down syndrome and has been experiencing unexplained nose bleeds for the past several months. His blood tests identify blast cells in the peripheral smear. In addition to nose bleeds, his acute leukemia will typically manifest which signs/symptoms? | Infections due to neutropenia
B) Fatigue due to RBC deficiency
D) Bleeding due to thrombocytopenia |
| Following peripheral blood testing and a bone marrow biopsy, a client has been diagnosed with
chronic myelogenous leukemia. Which of the following is most likely to have preceded the
client's diagnosis? | The presence of a Philadelphia chromosome |
| A client with chronic myelogenous leukemia (CML) has been diagnosed with terminal blast
crisis. Which of the following clinical manifestations should the nurse focus the assessment on
for this client? Select all that apply. | sob and progressive dyspnea
Headache and lethargy
D) Increasing confusion |
| A client has been diagnosed with non-Hodgkin lymphoma (NHL), a form of malignancy that
most likely originated in which of the following sites? | Lymph nodes |
| A young adult is preparing to begin treatment for non-Hodgkin lymphoma (NHL), a disease that
has disseminated widely. What is the most likely treatment regimen for this client? | Radiation and chemotherapy |
| The client is undergoing diagnostic workup for possible Hodgkin type of lymphoma. Which of
the following laboratory results would confirm the diagnosis of Hodgkin lymphoma? | Reed-Sternberg cells |
| A client is suspected of having Hodgkin lymphoma. Which of the following assessment findings
would confirm Hodgkin lymphoma rather than non-Hodgkin lymphoma? | Pruritus and night fevers |
| A client is undergoing a diagnostic workup to rule out multiple myeloma. Which of the
following diagnostic findings would confirm the diagnosis of multiple myeloma? | Plasma cells greater than 10% on bone marrow biopsy |
| Which of the following client complaints should prompt a clinician to order a diagnostic workup
for multiple myeloma? | “Lately my bones just seem to ache so badly, and nothing seems to help.” |
| Which of the following abnormal blood work results is most closely associated with a diagnosis
of multiple myeloma? | Low glomerular filtration rate and high calcium levels |
