Session 4 Pharm- 2 Word Scramble
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Question | Answer |
What is the difference between opiate and opioid | opiate is naturally derived drug from opium (morphine and Codeine) a opioid is a drug natural or synthetic with morphine like qualities |
A drug with addictive properties that can produce analgesic and sedative effects is termed what | narcotic |
What are the functional classifications of opioids | Agonist, Antagonist, Agonist/antagonist and other |
What type of drug is Fentanyl (Sublimaze, Duragesic) | Strong Opioid Agonist |
What type of drug is alfentanil, remifentanil and sufentanil | strong opioid agonist used for anesthesia related to fentanyl |
What type of drug is heroin | Strong Opioid Agonist that has no medical use |
What type of drug is Hydromorphone (Dilaudid) | Strong Opioid Agonist |
What type of drug is Meperidine (Demerol) | Strong Opioid Agonist |
What type of drug is methadone | Strong Opioid Agonist |
What type of drug is Morphine Sulfate (MS Contin) | strong opioid agonist |
What type of drug is Codeine (Robitussin AC) | Moderate Opioid Agonist |
What type of drug is Oxycodone (OxyContin) | Moderate Opioid Agonist |
What type of drug is Hydrocodone | Moderate Opioid Agonist |
Tylenol | 2,3,4 are combos of what drugs |
Vicodin and Lortab combine what drugs | acetaminophen/hydrocodone |
Vicoprofen combines what drugs | Ibuprofen/Hydrocodone |
Percocet is a combo of what drugs | acetaminophen/Oxycodone (class II schedule drug) |
What type of drug is Loperamide (Imodium) | weak opioid agonist |
What type of drug is Diphenoxylate (Lomotil) | Weak opioid Agonist combined with atropine |
What type of drug is Propoxyphene (Darvon | Weak Opioid Agonist combined with acetaminophen |
What type of drug is Dextromethorphan (Delsym, Robitussin DM) | Weak Opioid Agonist |
What type of opioid is Tramadol (Ultram( | Classified as Other opioid |
What type of drug is Pentazocine (Talwin | Opioid Agonist/antagonist |
What type of drug is Nalbuphine (Nubain) | Opioid Agonist/antagonist |
What type of drug is Butorphanol (Stadol) | Opioid Agonist/antagonist |
What type of drug is Naloxone (Narcan) | Opioid Antagonist |
What Type of drug is Naltrexone (ReVia) | Opioid Antagonist |
Define a schedule I controlled substance | no medical use high addiction potential (Heroin) |
Define a schedule II controlled substance | medical use but has high addiction potential (strong and moderate opioid agonists) |
Define a Schedule III controlled substance | Medical Use potential for dependence (Lortab, Tylenol |
Define a Schedule IV controlled substance | Medical Use low abuse potential (Weak Opioid agonists) |
What are the 5 types of opioids receptors | Mu "reap, Kappa "Sam", Delta, Epsilon, Sigma |
What is the Mu opioid receptor associated with in regards to opioids tx | REAP- respiratory depression, euphoria, analgesia, physical dependence |
What is the kappa opioid receptor associated with in regards to opioid tx | SAM- Sedation, Analgesia, Miosis |
What are the endogenous Opioids | Endorphins, Dynorphins, Enkephalins |
T/F the highest number of opioid MU receptors are found in the cerebral cortex | T |
Pain can be modified anywhere along the pain pathway where are the three main sites for opioids to exert their analgesic effects | Spinal Cord, Thalamus and Limbic System, Brainstem |
Opioids blocking pain in the spinal cord are typically modifying ascending pain signal (afferent) or Efferent pain signal | Inhibit release of neurotransmitters in spinal cord form afferents |
What are the contraindications for using morphine | respiratory compromise, Asthma, Intracranial injuries, Paralytic Ileus |
What are the adverse effects of morphine | euphoria, dysphoria, respiratory depression, Nausea, Constipation, sedation, pruritis, urticaria, bronchospasm, urinary retention, anxiety, hypotension. |
What schedule is morphine | schedule 2 |
What receptors does morphine act on | Mu (REAP- respiratory depression, euphoria, analgesia, physical dependence), Kappa (SAM- Sedation, Analgesia, Miosis) |
What options exists for route of delivery of morphine | PO, IV, SC, IM, PR |
What type of pain is morphine most effective on | visceral pain |
T/F morphine could potentially be given to suppress a cough | T |
What effect does morphine have on the skin | it causes histamine release and causes pruritis |
What effects does morphine have on the lungs besides respiratory depression | Bronchospasm avoid use in asthmatics |
If you give morphine to stop pain during labor what could you cause | prolongation of labor because it effects contractions of the uterus |
What is the half life of morphine | 2.5- 3 hours lose 90% in the first day |
What is the clinical uses for Methadone | absorbed well orally used in maintenance program for narcotic dependence treatment and powerful pain reliever |
Why is Meperidine (Demerol) a good pain relief choice for patients with biliary disease | it does not constrict the sphincter of Odi |
When is Meperidine (Demerol) contra indicated | pts receiving MAOI |
How much more potent is Fentanyl than morphine | 80-100 times |
Fentanyl comes in a dermal formula (Duragesic) what are some concerns with using this route | Easy overdose potential if pt forgets to take of previous patch and puts another one on (especially elderly) |
What are some common uses for Fentanyl (Sublimaze, Duragesic) | Used in epidurals, and transdermally (Duragesic) for chronic pain patients |
Apart from analgesia what positive effects does Codeine have | antitussive |
T/F Codeine has a high abuse potential | F it rarely produces dependence |
T/F propoxyphene a derivative of methadone is equal to aspirin in its analgesic effects | T so there is no real reason to prescribe in place of aspirin except for maybe when you are worried about aspirin toxicities |
What other drugs do you want to avoid giving with Tramadol (Ultram) | antidepressants Tramadol inhibits serotonin and norepi uptake like the antidepressants and can cause serotonin syndrome if combined |
What is the clinical use for Dextromethorphan | antitussive |
What is the clinical use for loperamide (Imodium and Diphenoxylate (Lomotil) | Antidiarrheal |
What is the use for buprenorphine (Subutex) | it is a partial agonist and can be used for outpatient opioid detox |
What is the only benefit of using the opioid agonist/antagonists pentazocine (Talwin), Nalbuphine (Nubain) and Butorphanol (Stadol) | They don't cause respiratory depression |
What use do Naloxone (Narcan) and Naltrexone (ReVia) have | they are opioid antagonists and can dramatically and completely reverse the effects of opioids |
What is one concern of using Naltrexone (ReVia) long term to treat addiction | it is very hepatotoxic |
Which has a longer half life Naloxone (Narcan) or Naltrexone (ReVia) | Naltrexone (ReVia) has a half life of about 48hrs; Narcan 1-2hrs |
Created by:
smaxsmith
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