PCol - Exam 2 Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
ACh | endogenous NT (not a good drug because rapidly metabolized); clinical use = produce complete miosis in eye surgery |
Methacholine | muscarinic selective, slightly longer duration of action; clinical use = bronchial airway hypersensitivity testing (diagnostic tool) |
Carbachol | carbamic acid derivative of ACh designed for longer duration of action (resists hydrolysis once bound to AChE); used in the eye to target the desired tissue, but not nicotinic/muscarinic selective; clinical use = produce complete miosis in eye surgery |
Bethanechol | added methyl to carbachol makes bethanechol; long-acting (resists hydrolysis) and selective for muscarinic receptors; bladder and GI hypotonia |
Pilocarpine | muscarinic agonist, binds AChE but resists hydrolysis (making it longer acting); used for treatment of open-angle glaucoma; natural product; can also be used clinically for Sjorgen’s syndrome |
Cevimeline | synthetic pilocarpine-like molecule; approved for Sjorgen’s syndrome |
Oxotremorine | muscarinic selective; long acting (resists AChE hydrolysis); clinical use = experimental model of Parkinson’s disease tremor |
Created by:
Krafty
Popular Science sets