BBC Pharm Word Scramble
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Question | Answer |
anti angiotensins include what class of drugs? | ACE-I, ARBs, aldosterone antagonists |
what diseases do anti angiotensins treat? | CHF, hypertension |
MOA of ACE inhibitors? | prevent conversion of Angiotensin I to Angiotensin II |
do ARBs cause cough? why or why not? | no, because it only blocks the receptor, so no increase in bradykinin, so no cough. blood pressure reduction tends to not be as significant. |
this is an aldosterone antagonist, blocking the effects of aldosterone. accordingly, it prevents aldosterone mediated effects, preventing the aldosterone mediate uptake of sodium and water. | spironolactone |
what type of diuretic is spironolactone? | potassium sparing diuretic. it blocks the aldosterone receptor |
adverse effects of spironolactone? | hyperkalemia, metabolic acidosis, hormone related sid eeffects (menstrual irregularities and gynecomastia). the latter effect is because of structural similarity to sex hormones. |
Created by:
aferdo01
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