ANS Receptors

 
 

 
 
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Receptor Type Location Action
M1- CholinergicCNSIP3DAG Increase Calcium
M2- CholinergicHeartIncrease cAMP, Potassium
M3-CholinergicSmooth Muscle, Glands, Circular IrisIP3DAG, Allow Drainage from Schlemm, Constrict Pupil, Accomodation, Increase GI motility/Secretions
Alpha1- AdrenergicPostsynaptic- smooth muscleIP3DAG, Vasoconstrict, Sphincter Constrict, Relax Detrusor, Dilate Pupil
Alpha2- AdrenergicPreSynaptic- Smooth Muscle, Fat, Platelets, Nerve TerminalDecrease cAMP
Beta1- AdrenergicHeartIncrease cAMP, Increase HR and Contractions
Beta2- AdrenergicSmooth Muscle/Cardiac Vessels, GI, UrinaryIncrease cAMP, Eye Dilator, Relax Detrusor, Relax GI
Beta3- AdrenergicFatIncrease cAMP
D1RenalIncrease cAMP
D2-4CNSDecrease cAMP