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ANS Receptors

B. Busey ANS Receptors

Receptor TypeLocationAction
M1- Cholinergic CNS IP3DAG Increase Calcium
M2- Cholinergic Heart Increase cAMP, Potassium
M3-Cholinergic Smooth Muscle, Glands, Circular Iris IP3DAG, Allow Drainage from Schlemm, Constrict Pupil, Accomodation, Increase GI motility/Secretions
Alpha1- Adrenergic Postsynaptic- smooth muscle IP3DAG, Vasoconstrict, Sphincter Constrict, Relax Detrusor, Dilate Pupil
Alpha2- Adrenergic PreSynaptic- Smooth Muscle, Fat, Platelets, Nerve Terminal Decrease cAMP
Beta1- Adrenergic Heart Increase cAMP, Increase HR and Contractions
Beta2- Adrenergic Smooth Muscle/Cardiac Vessels, GI, Urinary Increase cAMP, Eye Dilator, Relax Detrusor, Relax GI
Beta3- Adrenergic Fat Increase cAMP
D1 Renal Increase cAMP
D2-4 CNS Decrease cAMP
Created by: bbusey on 2008-03-16



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