PHAR134 exam 2 Drugs Word Scramble
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Question | Answer |
Carbachol | nonselective cholinergic agonist (carbamate bioisostere, less prone to HOH) |
Acetylcholine | nonselective cholinergic agonist |
Methacholine | selective muscarinic agonist (less prone to HOH) |
Pilocarpine | selective muscarinic agonist (tertiary amine) |
Bethanechol | selective muscarinic agonist (long acting) |
Muscarine | selective muscarinic agonist |
Edrophonium | competitive, reversible AChE inhibitor |
Donepezil | competitive, reversible AChE inhibitor (tertiary) |
Pyridostigmine | noncompetitive, reversible AChE inhibitor (slow onset, long duration) |
Neostigmine | noncompetitive, reversible AChE inhibitor (rapid onset, intermediate duration) |
Physostigmine | noncompetitive, reversible AChE inhibitor (tertiary) |
Demercarium | noncompetitive, reversible AChE inhibitor |
Ambenonium | noncompetitive, reversible AChE inhibitor |
Echothiophate | irreversible AChE inhibitor |
Parathion | irreversible AChE inhibitor |
Malathion | irreversible AChE inhibitor |
Sarin | irreversible AChE inhibitor |
Soman | irreversible AChE inhibitor |
Tabun | irreversible AChE inhibitor |
Pralidoxime | organophosphate poisoning antidote |
Homatropine | direct acting anticholinergic (topical admin=local effect) |
Tropicamide | direct acting anticholinergic (topical admin=local effect) |
Cyclopentolate | direct acting anticholinergic (topical admin=local effect) |
Atropine | direct acting anticholinergic |
Scopolamine | direct acting anticholinergic |
Ipratropium | direct acting anticholinergic (quaternary) |
Tiotropium | direct acting anticholinergic (quaternary) |
Dicyclomine | direct acting anticholinergic |
Oxybutynin | direct acting anticholinergic |
Tolterodine | direct acting anticholinergic (selectivity for bladder tissue) |
Trospium | direct acting anticholinergic (quaternary) |
Solifenacin | direct acting anticholinergic (selective M3>M1) |
Darifenacin | direct acting anticholinergic (selective M3>M1) |
Glycopyrrolate | direct acting anticholinergic (quaternary) |
Hemicholinium | indirect acting anticholinergic - block active transport of choline into nerve terminal |
Vesamicol | indirect acting anticholinergic - block transport of ACh into vesicle |
Botulinum toxin | indirect acting cholinergic - prevent vesicle fusion & release of ACh |
Nicotine | nicotinic agonist |
DMPP | nicotinic agonist (selective for autonomic ganglionic cells) |
Hexamethonium | ganglionic blocker |
Trimethaphan | ganglionic blocker |
Mecamylamine | ganglionic blocker |
Isoproterenol | nonselective beta agonist |
Dobutamine | beta-1 selective agonist |
Metaproterenol | short acting beta-2 selective agonist |
Terbutaline | short acting beta-2 selective agonist |
Albuterol | short acting beta-2 selective agonist |
Salmeterol | long acting beta-2 selective agonist |
Formoterol | long acting beta-2 selective agonist |
Phenylephrine | alpha-1 selective agonist |
Tetrahydrozoline | alpha-1 selective agonist |
Naphazoline | alpha-1 selective agonist |
Clonidine | alpha-2 selective agonist |
Amphetamine | indirect adrenergic agonist - releasing agent |
Methamphetamine | indirect adrenergic agonist - releasing agent |
Cocaine | indirect adrenergic agonist - reuptake inhibitor |
Selegiline | indirect adrenergic agonist - MAO inhibitor |
Ephedrine | mixed action adrenergic agonist. direct alpha & beta, and indirect acting (erythro isomer) |
Pseudoephedrine | mixed action adrenergic agonist. predominately indirect acting(threo isomer) |
Phentolamine | nonselective alpha antagonist |
Phenoxybenzamine | nonselective alpha antagonist |
Prazosin | selective alpha-1 antagonist |
Terazosin | selective alpha-1 antagonist (+ apoptosis of prostate cells) |
Doxazosin | selective alpha-1 antagonist (+ apoptosis of prostate cells) |
Alfuzosin | selective alpha-1 antagonist |
Tamsulosin | selective alpha-1a antagonist |
Silodosin | selective alpha-1a antagonist |
Yohimbine | selective alpha-2 antagonist |
Propranolol | nonselective beta antagonist |
Pindolol | nonselective beta antagonist + ISA |
Metoprolol | selective beta-1 antagonist |
Atenolol | selective beta-1 antagonist |
Labetolol | nonselective beta antagonist + alpha-1 antagonist |
Carvedilol | nonselective beta antagonist + alpha-1 antagonist + anti-inflammatory |
Reserpine | indirect andrenergic antagonist - block vesicular monoamine transporter, depleting NE |
Tyramine | indirect adrenergic antagonist - "false transmitter" that displaces NE |
Metyrosine | indirect adrenergic antagonist - inhibit tyrosine hydroxylase (TH) |
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