Anti-Infective Drugs
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| What Drugs are used for Tx of UTI, sinuses, lower resp. tract, GI, skin, bones, joints and Gonorrhea? | QUINOLONES:ciprofloxacin (Cipro), levofloxacin (Levaquin)
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| If pt is allergic to other antibiotics use this durg? | QUINOLONES
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| Before initiating a quinolone...? | C&S tests should be drawn to identify the causative organism.
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| Side effects of quinolones include: | N/V/D, abd pain, colitis, headache,dizzy Crystalluria, Superinfection, Phototoxicity, cartilage or tendon damage.
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| Use caution w/ quinolones and...? | elderly, GI disease, or arteriosclerosis, Strenuous exercise, (Tendon rupture)Seizure disorder. renel impairment
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| A broad-spectrum antibiotic used in Tx of rickets, chlap, Rocky Mtn. Fever, ACNE...? | Tetracyclines
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| Used to treat H. pylori infection? | Tetracyclines
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| Unfortunate sided effect of tetracyclines? Take it at what time of day? | discolored teeth in the young. Cant take if younger than 8yo. b/c of bone retard. Morning
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| Avoid taking________ with tetracyclines? | Antacids, Ca, Mg laxatives, Fe, Zn, Antidearrhea agents kaolin pectin or bismuth. Dairy products, Oral Contraceptives
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| If you dont discard expired drugs, _____ can result form taking outdated drugs. | Nephrotoxicity
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| What durgs are used to treat specific susceptible fungi? | Antifungals
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| What is the antifungal of choice? ppl w/ AIDS | Amphotericin B (IV)
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| Amphotericin B has severe side effects so... pt require...? | close medical supervision (hospitialization)
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| Side effects fo Amphotericin B include?: | Headache, chills, Fever-tachypnea, hypotension. Nephrotoxicity-(BUN, Cretine, Output measured) Hypokalemia
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| lipid based product that increases tolerability of antifungals ? | Abelcet
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| What drug is used to treat candidial infections? (yeast infections) | Fluconazole (Dyflucan)
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| What drug will cancel Fluconazole? | Rifampin- leads to clincal failure of fluconazole
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| Extreme caution w/ fluconazole and ...? | kids <13, preg, nursing, Hepatic or renal disease. Nephrotoxic!
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| What durg is administered PO, Tx of specific fungi causing tinea infections..? (Ringworm) | Griseofulvin
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| Side effects of Griseofulvin include:? | THIRST, headache, hypersensitivity reactions, photosensitivity.
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| Use caution w/ on Griseofulvin? | Kid <2, Preg, Liver dysfunction, Porphyria, Penicillin hypersensitivity
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| Avoid _____ while taking Griseofulvin. | Alcohol, Phenobarbital, coumarin, oral contraseptives
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| This drug is used to Tx (PO), of intestinal candidiasis. Or topically for Tx of Diaper Rash? | Nystatin (Mycostatin)
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| Antituberculosis agents are given for 2 purposes: | 1)Tx asymptomatic infection
2)Tx of active clinical TB & to prevent relapse
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| For asymptomatic TB. Tx consist of ...? How long? | daily isoniazid (INH) alone for 6-12 mths to prevent devel. of disease.
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| Alternate Tx of asymptomatic TB or INH-resistant use these drugs for Tx? | rifampin w/pyrazinamide
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| Tx of clinical TB is challenging for 2 reasons:? | 1)Increasing incidence of TB,high-risk pop.
2)resistant to drugs or imcompletion of 6-24 mth Tx.
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