Trunichy: Hypochromic Microcytic Anemia
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Deficiency in __ or ___ | Heme or globin chain synthesis
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Result of deficiency in heme synthesis | Iron deficiency
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Result of deficiency in globin synthesis | Thalassemia
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Major storage form of iron | Ferritin
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Ferritin synthesis is directly proportional to... | Total iron stores
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Long term storage form of iron | Hemosiderin
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What stain is used to see hemosiderin? | Prussian blue
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Serum iron binding protein | Transferrin
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Serum iron measures... | Transferrin bound iron
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Use TIBC to discriminate between ___ and ___ | IDA and ACD
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Normal transferrin saturation | 30%
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Pt presents with: Decreased serum ferritin Decreased serum iron Increased TIBC Decreased %saturation What's the Dx? | Iron deficiency anemia
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Two substances that can cause Acquired Sideroblastic Anemia | Alcohol and Lead
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Inhibitory cytokines that adversely impact erythropoiesis | TNF-B
IL-1/6
INF-gamma
Hepcidin
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One of the most common human diseases | IDA
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Soluble iron storage form | Ferritin
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