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Turnicky 02 Hypo/Mic

Trunichy: Hypochromic Microcytic Anemia

Deficiency in __ or ___ Heme or globin chain synthesis
Result of deficiency in heme synthesis Iron deficiency
Result of deficiency in globin synthesis Thalassemia
Major storage form of iron Ferritin
Ferritin synthesis is directly proportional to... Total iron stores
Long term storage form of iron Hemosiderin
What stain is used to see hemosiderin? Prussian blue
Serum iron binding protein Transferrin
Serum iron measures... Transferrin bound iron
Use TIBC to discriminate between ___ and ___ IDA and ACD
Normal transferrin saturation 30%
Pt presents with: Decreased serum ferritin Decreased serum iron Increased TIBC Decreased %saturation What's the Dx? Iron deficiency anemia
Two substances that can cause Acquired Sideroblastic Anemia Alcohol and Lead
Inhibitory cytokines that adversely impact erythropoiesis TNF-B IL-1/6 INF-gamma Hepcidin
One of the most common human diseases IDA
Soluble iron storage form Ferritin
Created by: bcriss