drugs for test 3
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| donepezil | ACh inhibitor; used for the treatment of Alzheimer's Disease
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| galantamine | ACh inhibitor; used for the treatment of Alzheimer's Disease
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| rivastigmine | ACh inhibitor; used for the treatment of Alzheimer's Disease
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| memantine | NMDA antagonists; used for the treatment of Alzheimer's Disease
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| L-dopa/Carbidopa | increase dopamoine synthesis; Treatment of Parkinson's Disease
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| Rasagiline | MOA-B inhibitor; treatment of Parkinson's disease
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| Apomorphine | dopamine receptor agonist; treatment of Parkinson's disease
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| Tolcapone/Entacapone | COMT inhibitor; treatment of Parkinson's Diseas
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| Selegiline | MOA-B inhibitor--low dosage is for treatment of Parkinson's Disease
MOA-A inhibitor; large doses used for treatment of depression
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| amantadine | NMDA antagonist; treatment of Parkinson's disease and Influenza A (uncoating and release inhibitor)
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| chlorpromazine | typical antipsychotic; treatment of schizophrenia
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| fluphenazine | typical antipsychotic; treatment of schizophrenia
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| haloperidol | typical antipsychotic; treatment of schizophrenia and behavioral syndromes accompanied by motor disturbances
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| clozapine | atypical antipsychotic; treatment of schizophrenia
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| risperidone | atypical antipsychotic; treatment of schizophrenia and bipolar disorder
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| lithium | first-line/standard treatment for bioplar disorder
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| valproate | anticonvulsant; treatment of seizures and bipolar disorder
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| carbamezepine | anticonvulsant; treatment of seizures and bipolar disorder
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| lamotrigine | anticonvulsant; treatment of seizures and bipolar disorder
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| amitriptline | tricyclic antidepressant (TCA); treatment of depression
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| bupropion | atypical antidepressant; treatment of depression
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| mirtazapine | atypica depressant; treatment of depression and insomnia
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| venlafaxine | 5-HT/NE reuptake inhibitor (SRNI)
treatment of depression
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| fluoxetine | serotonin selective reuptake inhibitor (SSRI); treatment of depression
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| paroxetine | serotonin selective reuptake inhibitor (SSRI); treatment of depression
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| sertraline | serotonin selective reuptake inhibitor (SSRI); treatment of depression
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| alprazolam | benzodiazepine (anxiolytic); treatment of anxiety
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| diazepam | benzodiazepine (anxiolytic); treatment of anxiety and skeletal muscle relaxtion and status epiepticus
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| buspirone | non-benzodiazepine (anxiolytic); treatment of anxiety
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| propranolol | non-benzodiazepine (anxiolytic (copletivitie Beta 1 and beta 2 blocker); treatment of performance anxiety
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| flumazenil | benzodiazepine receptor antagonist
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| temazepam | benzodiazepine for insomina
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| zaleplon | non-benzodiazepine receptor agonist for insomnia (NBRAs)
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| zolpidem | non-benzodiazepine receptor agonist for insomnia (NBRAs)
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| ramelteon | melatonin receptor agonists for insomnia
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| phenytoin | antiseizure drug
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| valproc aicd | antiseizure drug
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| phenobarbital | barbiurate; antiseizure drug
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| felbamate | glutamate receptor inhibitor; antiseizure drug
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| d-tuoburarine | non-depolarizing; nicotinic antagonists; NM blocker; skeletal muscle relaxer
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| succinylcholine | depolarizing; nicotinic antagonists; NM blocker; skeletal muscle relaxer
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| botulinum toxin | motor nerve blocker; skeletal muscle relaxer
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| baclofen | gaba analogue; skeletal muscle relaxer
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| cyclobenzaprine | skeletal muscle relaxer
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| tizanidine | alpha 2 agonists; skeletal muscle relaxer
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| dantrolene | skeletal muscle relaxer
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| oseltamivir | uncoating and release inhibitor; treatment of influenza A & B
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| acyclovir | dna replication inhibitor, purine derivatives; Treatment of Herpes simplex virus (HSV-1 & HSV-2), Epstein-Barr virus (EBV, infectious mononucleosis); Varicella-zoster virus (VZV, chickenpox); Cytomegalovirus (CMV)
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| zidovudine | RNA replication inhibitors
Nucleoside Reverse Transcriptase Inhibitors
Treatment OF HIV-1, HIV-2, Cytomegalovirus CMV (some)
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| nevirapine | RNA replication inhibitors
Non-nucleoside Reverse Transcriptase Inhibitors
Treatment of HIV-1
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| saquinavir | RNA replication inhibitors
Protease inhibitors: Peptidomimetics
Treatment of HIV-1/2
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| cyclophosphamide | Alkylating agents: Nitrogen Mustards
Cell Cycle Nonspecific Drugs
Treatment of Cancer: Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Breast, Ovarian
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| methotrexate | Antimetabolites: Folate antagonists Cell Cycle Specific Drugs
Treatment of Cancer: Acute Lymphatic Leukemia, CNS leukemia (IT), Gestational Trophoblastic Neoplasia, Breast, : Non-Hodgkin's Lymphoma
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| vincristine | Natural Products--Microtubule inhibitor
Cell Cycle Specific Drugs
Treatment of Cancer: Huntington's Disease, : Non-Hodgkin's Lymphoma, Brain, Acute Lymphatic Leukemia
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| trastuzumab | Monoclonal antibodies
Treatment of cancer: Breast (25% 1o tumors, HER2 overexpress), Prostate, Pancreatic, Lung, Ovarian
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| imatinib | Protein-tyrosine kinase inhibitors
Treatment of cancer: Chronic Myeloid Leukemia (Ph+), Gastrointestinal Stromal Tumor, Acute Lymphatic Leukemia (Ph+),
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| penicillin G | Inhibitors of cell wall synthesis
Therapeutic Use (Narrow Spectrum): Penicillin G
– Streptococcus pneumoniae, Neisseria gonorrhea, Peptococcus magnus, Clostridium perfringens, Trepnema pallidum
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| piperacillin | Inhibitors of cell wall synthesis
Therapeutic Use (Broad Spectrum, > G-): Piperacillin
– Streptococcus pneumoniae, Neisseria gonorrhea, Haemophilus influenzae, Escherichia coli, Pseudomonas aeruginosa, Morganella morganii, Citrobacter freundii, etc..
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| cefazolin | Inhibitors of cell wall synthesis
Therapeutic Use (1st Generation): Cefazolin
– MSSA, MSSE, Streptococcus pneumoniae, Streptococcus pyogenes, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae
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| cefeprime | Inhibitors of cell wall synthesis
Therapeutic Use (4th Generation): Cefepime (gram -)
– As 1st Generation, Haemophilus influenzae, Neisseria gonorrhoeae, Proteus vulgaris, Serratia marcescens, Acinetobacter calcoaceticus, Pseudomonas aeroginosa, etc..
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| vancomycin | Inhibitors of cell wall synthesis
Therapeutic UseGram (+)
– MRSA, MRSE, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Enterococcus faecalis, Clostridium difficile
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| gentamicin | Inhibitors of protein synthesis
Therapeutic Use
– G- aerobes: Francisella tularensis, Klebsiella pneumoniae + Piperacillin, Enterococcus fecaelis + Ampicillin, Streptococcus agalactiae + Ampicillin
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| azithromycin | Inhibitors of protein synthesis
Therapeutic Use Respiratory Tract Infections
– Streptococcus pneumoniae, Haemophilus influenzae , Moraxella catarrhalis, Legionella pneumophila , Chlamydia trachomatis, Mycobacterium avium-intracellulare
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| sulfamethozazole + trimethoprim | Antimetabolites
Therapeutic Use (UTI treatment)
– Listeria monocytogenes, Escherichia coli, Haemophilus influenzae, Legionella pneumophilia, Proteus mirabilis, Salmonella typhi, Shigella dysenteriae, Pneumocystis jiroveci
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| levofloxacin | Inhibitors of DNA gyrase
Therapeutic Use
– Streptococcus pneumoniae, Escherichia coli, Bacillus anthracis, Haemophilus influenzae, Legionella pneumophilia, Proteus mirabilis, Shigella dysenteriae,
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