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Lecture Unit 1

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Question
Answer
Prenatal period   First 38 weeks of human development. Scientific weeks.  
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Pre-embryonic period   Weeks 1-2  
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Embryonic period   Weeks 3-8  
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Fetal period   Weeks 9-38  
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Fertilization   When sperm enters egg. Occurs in the uterine tube.  
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Zygote   When genetic material mixes  
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Cleavage   Cell division  
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Morula   16 cell stage  
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Blastocyst   Composed of 2 parts: Trophoblast-becomes the fetal half of placenta & Embryoblast, Aka: inner cell mass (ICM)-becomes the embryo.  
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Trophoblast   2 layers: Cytotrophoblast: inner layer & Synctiotrophoblast: Outer layer. Layers form the Chorion which creates fetal part of placenta.  
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The Bilaminar disc   ICM divides. 2 sheets of cells: epiblast (top) & hypoblast (bottom). Epiblast forms embryo & Amnion. Hypolast forms yolk sac.  
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Embryonic period: Formation of Three germ layers   Embryonic period. Primitive streak appears on dorsal surface of epiblast. Gastrulation. Cells that invaginate form mesoderm and endoderm. Remaining cells: ectoderm. Hypoblast regresses.  
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Gastrulation   epiblast cells invaginate (move) through the primitive streak towards the hypoblast.  
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Body folding   Transverse: L & R sides of embyo curve toward midline. Forms cylindrical trunk w/ ectoderm covering exterior. Cephalocaudal: In head and tail regions. Creates future head and butt  
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Ectoderm derivatives   Skin and nervous tissue  
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Endoderm derivatives   Digestive and respiratory systems  
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Mesoderm derivatives   Muscle, tissue, heart, kidneys, reproductive organs  
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Neurulation   The notochord, a tube of mesoderm, forms parallel & deep to primative streak. It stimulates ectoderm to form the neural tube which becomes brain & spinal cord.  
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Induction   One structure influencing another structure to change form  
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Organogenesis   Organ development follows gastrulation and body folding. Most organ systems have developed by week 8. Embryo 1" long.  
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Fetal Period   Growth and maturation of organs  
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Birth defects   3/100 in US have serious structural birth defect. Causes of 50% of birth defects are unknown.  
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Teratogen   Anything that causes a birth defect. Embryo particularly sensitive during embryonic period.  
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Fetal Alcohol Syndrome (FAS)   Preventable. Growth retardation, heart defects, microcephally (small brain), leading cause of mental retardation.  
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Accutane   25% of bables born to mothers taking Accutane have serious birth defects and 50% are mentally disabled.  
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