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Microbiology CH 8

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Question
Answer
What are the body's first lines of defense against foreign invasion of microbes?   skin, membranes, secretions  
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What happens when the first defensive lines are penetrated?   creates an opening for invasion of microbes  
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How does a fever help the body?   stimulates production of IL-1, stimulates migration of leukocytes to infection to kill pathogens, reduces iron which limits growth of iron-requiring pathogens  
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How does the inflammatory response help the body?   prevents, further spread of pathogen, localizes and contains the infection, contains and neutralizes toxins, aids in repair of damaged tissues  
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What are the outward signs of inflammation?   swelling (edema), redness (blood flow to the area), heat, pain and pus formation  
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How can you recognize an anaphylactic reaction?   itching, flushing, headache, ringing in ears, metallic taste in mouth, difficulty breathing, elevated blood pressure, increased heart rate, restlessness  
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How is an anaphylactic reaction treated?   administer 100% oxygen, inject epinephrine and steroids, start IV fluids, inject Levophed (vasopressor agent used to increase blood pressure)  
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What are autoimmune diseases?   Caused by person's immune system not recognizing a body tissue as being a normal part of the body. The body attempts to destroy the tissue perceived as foreign. Examples: lupus, multiple sclerosis, rheumatiod arthritis and Crohn's disease  
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Why is it important to match blood from a blood bank with the patient's own?   If mismatched, a transfusion reaction will occur.  
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What can happen if mismatched blood is administered?   SOB, rapid pulse, skin pallor, diffuse loss of blood at surgical site, decreased blood oxygen saturation  
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What can be done for the patient if mismatched blood is administered?   stop blood transfusion, steroids are given, urine output is monitored, dialysis may be indicated  
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peristalsis   successive waves of involuntary contraction passing along the walls of a hollow muscular structure (as the esophagus or intestine) and forcing the contents onward compare  
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wandering phagocyte   mobile macrophages that migrate to the infected area  
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lymphokine   any lymphocyte product, as interferon, that is not an antibody but may participate in the immune response through its effect on the function of other cells  
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invaginate   to fold in so that an outer becomes an inner surface  
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Second line of defense   phagocytes, complement and other blood products, interferon, fever production, iron and balance and the inflammatory response  
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Specific phagocytic cells   granulocytes and macrophages  
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neutrophils   most abundant and efficient phagocytes  
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eosinophils   play a efficient phagocytic role during the allergic response  
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two types of macrophages   mobile and fixed  
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fixed macrophage   traps and engulfs foreign debris  
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phagocytosis   engulfing of bacteria and debris  
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Function of lymph nodes   remove microbes from lymph before they reach major ducts that empty into the blood stream  
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