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Lab quiz 2-Small intestine, protein digestion, H2O absorption

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What is the small intestine mostly responsible for?   digestion and absorption  
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How long are the duodenum, jejunum, ileum   10", 8', 12'  
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What are the four layers of the wall of the SI   mucosa, submucosa, muscularis externa, serosa  
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Where does most digestion take place   the SI  
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What is the main source of digestive enzymes   pancreas  
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What are the specializations of the mucosa and submucosa   plicae circularis or valves of Kerckrings (3x size increase) villi (10x) microvilli (20x)  
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What disease causes serious decrease in surface area   celiac disease-no villi  
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What is a lacteal   a central lymphatic duct in each villus for removal of intestinal lymph  
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What types of fatts go through the lacteal first   chylomicrons  
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What vessles supply the stomach and spleen, intestine and pancreas, intestine   celiac a, sup mesent a, inf mesent a  
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What arteries supply the liver   Hepatic & portal  
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What vein leaves the liver   hepatic v  
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How do lipophilic molecules cross cell membrane   simple diffusion  
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How do hydrophilic molecules cross the cell membrane   special transport systems such as channels or carriers  
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What is secondary active transport   driven by the Na+ gradient  
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What is primary active transport   driven by metabolic energy  
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How can some large cells enter the cell   by endocytosis  
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What activates pepsinogen   acid  
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What activates trypsinogen   intestinal protease enterokinase  
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T/F all luminal proteases are endopeptidases   T  
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What is the function of pepsin   not very important for protein digestion, acts only on aromatic AAs, inactivated as soon as chyme enters duod  
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Where does the final breakdown into absorbable units occur   in the brush border and catalyzed enzymes bound to the brush border membrane = contact digestion  
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Where are proteins digested   stomach  
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Where are proteases digested   lumen of SI  
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Where are polypeptides and AAs digested   brush border of SI  
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Where are AAs, dipeptides, tripeptides digested   enterocytes  
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Name the 5 zymogens   trypsinogen, chymotrypsinogen, proelastase, procarboxypeptidase A & B-the inactive forms  
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Where is absorption of proteins usually completed   mid jejunum, not totally complete until all di/tripeptides are taken up into the cell  
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Where do proteins in the colon come from   largely from intestinal bacteria and sloughed off cells that are egested  
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What is the daily water intake   1.5-2 L  
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What % of water intake is from solid food   80%  
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Where does most of the H2O absorption take place   SI  
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Which tubes in the experiment had the most protein hydrolysis   1ml .03 % boiled protease & ice cold protease  
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What color indicates a positive test for protein digestion   dark blue  
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Under what conditions is protease most effective   37 degrees C and 5-6pH  
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What color indicates a neg protein digestion test   light blue  
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What is the vitamin required in AA metab   B6  
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Where is pepsin inactivated   the pancreas  
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What prevents pancreatic proteases from digesting the pancreas   trypsin inhibitor( inhibits trypsinogen)  
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