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Physiology

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Question
Answer
Major site of water reabsorption in GI   jejunum > ileum > colon  
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Most effective nephron site for acid excretion   proximule tubule  
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Nephron site for ADH effect   collecting duct  
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Nephron site for greatest generation of free water   thick ascending limb of medulla  
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Compression of thorax under water pruduces:   a restrictive pattern of PFTs  
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Constriction of efferent arteriole:   increases GFR and decreases renal plasma flow  
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Starling equation for GFR   GFR = Kf[(Pgc-Pbs) - "pi"gc)], where Kf = filtration coefficient, Pgc = hydrostatic pressure in glomerular capillary, Pbs = hydrostatic pressure in bowman's space; "pi"gc = oncotic pressure in glomerular capillary  
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Filtration fraction in glomerulus   FF = GFR/RPF  
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Constriction of afferent arteriole   no change in FF (dec GFR / dec RPF)  
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constrict efferent arteriole   increases FF (inc GFR / dec RPF)  
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increase plasma protein concentration (inc osmotic pressure of glomerular capillary)   decreases the FF; (dec GFR / no change in RPF)  
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decreasing plasma protein concentration (dec oncotic pressure)   increases FF (inc GFR / no change in RPF)  
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Constriction of ureter, decreases Pbs and decreases GFR   FF dec w/o affecting RPF (dec GFR / no change in RPF)  
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Negative charge of GBV   maintained by heparan sulfate  
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S1 heart sound correlates with   C wave in jugular venous pulses (closure of tricuspid valve)  
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Carotid massage   dec heart rate and increases vasodilation (innervated by CNIX and X; impulses inhibit tonic discharge of vasoconstrictor nerves and excite vagal innervation of heart = vasodilation/venodilation, drop in bp and hr, and dec CO  
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