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BR-5
Physiology
| Question | Answer |
|---|---|
| Major site of water reabsorption in GI | jejunum > ileum > colon |
| Most effective nephron site for acid excretion | proximule tubule |
| Nephron site for ADH effect | collecting duct |
| Nephron site for greatest generation of free water | thick ascending limb of medulla |
| Compression of thorax under water pruduces: | a restrictive pattern of PFTs |
| Constriction of efferent arteriole: | increases GFR and decreases renal plasma flow |
| Starling equation for GFR | GFR = Kf[(Pgc-Pbs) - "pi"gc)], where Kf = filtration coefficient, Pgc = hydrostatic pressure in glomerular capillary, Pbs = hydrostatic pressure in bowman's space; "pi"gc = oncotic pressure in glomerular capillary |
| Filtration fraction in glomerulus | FF = GFR/RPF |
| Constriction of afferent arteriole | no change in FF (dec GFR / dec RPF) |
| constrict efferent arteriole | increases FF (inc GFR / dec RPF) |
| increase plasma protein concentration (inc osmotic pressure of glomerular capillary) | decreases the FF; (dec GFR / no change in RPF) |
| decreasing plasma protein concentration (dec oncotic pressure) | increases FF (inc GFR / no change in RPF) |
| Constriction of ureter, decreases Pbs and decreases GFR | FF dec w/o affecting RPF (dec GFR / no change in RPF) |
| Negative charge of GBV | maintained by heparan sulfate |
| S1 heart sound correlates with | C wave in jugular venous pulses (closure of tricuspid valve) |
| Carotid massage | dec heart rate and increases vasodilation (innervated by CNIX and X; impulses inhibit tonic discharge of vasoconstrictor nerves and excite vagal innervation of heart = vasodilation/venodilation, drop in bp and hr, and dec CO |