Cholinergic and Cholinergic Blocking Agents
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| What are the Cholinergic Effects? (6) | SLUDGE: Salivation, Lacrimation, Urination, Diarrhea, GI motility increased, Emesis
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| What are the therapeutic uses of Cholinergic Agents? (4) | 1. reduction of intraocular pressure in glaucoma or eye surgery; 2. post surgical bladder or intestinal atony; 3. diagnosis and treatment of myasthenia gravis; 4. Tx of Alzheimer's Disease
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| Adverse effects of Bethan(Urecholine) and Physostigmine (Antirilium)? | Bradycardia, Hypotension, Headache, dizziness, abdominal cramping, N&V, bronchospams, increased bronchial secretions;
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| S/S of Cholinergic Crisis? (5) | hypotension, bradycardia, bloody diarrhea, shock, cardiac arrest;
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| The Nurse would use what reversal agent for a toxicity/OD of Bethan(Urecholine) or Physostigmine (Antirilium)? | Reversal agent is Atropine
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| Mechanism of action for Bethan(Urecholine)? | Direct cholinergic that stimulates receptors in the bladder. increases bladder tone and mobility, relaxes sphincter;
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| Therapeutic uses for Bethan(Urecholine)? (4) | 1. acute post op and post partum nonobstructive urinary retention; 2. neurogenic atony of bladder with urinary retention; 3. Chronic Refractory heartburn4. Diagnostic Test for cystic fibrosis
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| Contraindications for Bethan(Urecholine)and Physostigmine (Antirilium)? (7) | 1. Hyperthyroidism2. Pueptic Ulcer Disease3. active bronchial asthma4. cardiac disease5. CAD6. Epilepsy7. Parkinson's Disease
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| Mechanism of Action for Physostigmine (Antirilium)? | cholinergic agent that inhibits acetetylcholinesterase
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| Therapeutic uses of Physostigmine (Antirilium)? (2) | 1. Symptomatic Tx of myasthenia gravis2. antidote for anticholinergic OD/toxicity
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| Patient teaching for Bethan(Urecholine) and Physostigmine (Antirilium)? (4) | 1. take meds as ordered by MD2. space doses evenly apart3. CAll MD if develope muscle weakness, abdominal cramps, diarrhea, difficulty breathing;4. for pts. with myasthenia gravis, take 30 minutes before eating to improve chewing and swallowing
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