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Cholinergic RX

Cholinergic and Cholinergic Blocking Agents

QuestionAnswer
What are the Cholinergic Effects? (6) SLUDGE: Salivation, Lacrimation, Urination, Diarrhea, GI motility increased, Emesis
What are the therapeutic uses of Cholinergic Agents? (4) 1. reduction of intraocular pressure in glaucoma or eye surgery; 2. post surgical bladder or intestinal atony; 3. diagnosis and treatment of myasthenia gravis; 4. Tx of Alzheimer's Disease
Adverse effects of Bethan(Urecholine) and Physostigmine (Antirilium)? Bradycardia, Hypotension, Headache, dizziness, abdominal cramping, N&V, bronchospams, increased bronchial secretions;
S/S of Cholinergic Crisis? (5) hypotension, bradycardia, bloody diarrhea, shock, cardiac arrest;
The Nurse would use what reversal agent for a toxicity/OD of Bethan(Urecholine) or Physostigmine (Antirilium)? Reversal agent is Atropine
Mechanism of action for Bethan(Urecholine)? Direct cholinergic that stimulates receptors in the bladder. increases bladder tone and mobility, relaxes sphincter;
Therapeutic uses for Bethan(Urecholine)? (4) 1. acute post op and post partum nonobstructive urinary retention; 2. neurogenic atony of bladder with urinary retention; 3. Chronic Refractory heartburn4. Diagnostic Test for cystic fibrosis
Contraindications for Bethan(Urecholine)and Physostigmine (Antirilium)? (7) 1. Hyperthyroidism2. Pueptic Ulcer Disease3. active bronchial asthma4. cardiac disease5. CAD6. Epilepsy7. Parkinson's Disease
Mechanism of Action for Physostigmine (Antirilium)? cholinergic agent that inhibits acetetylcholinesterase
Therapeutic uses of Physostigmine (Antirilium)? (2) 1. Symptomatic Tx of myasthenia gravis2. antidote for anticholinergic OD/toxicity
Patient teaching for Bethan(Urecholine) and Physostigmine (Antirilium)? (4) 1. take meds as ordered by MD2. space doses evenly apart3. CAll MD if develope muscle weakness, abdominal cramps, diarrhea, difficulty breathing;4. for pts. with myasthenia gravis, take 30 minutes before eating to improve chewing and swallowing
Created by: Annie Laurie Migues Annie Laurie Migues on 2010-04-18



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