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Antibiotics

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Question
Answer
Systemic infection in which pathogens are present in the circulating bloodstream   Septicemia  
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Syndrome involving multiple system organ involvement that is a result of microorganisms or their toxins circulating in the blood   Sepsis  
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Invasion of body by pathogenic microorgs that reproduce and multiply, causing disease   Infection  
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Localized presence and multipication of microorgs w/out invasion or damage   Colonization  
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Presence of viable bacteria in the blood   Bacteremia  
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Staphylococcus category   Gram-positive cocci  
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Streptococcus category   Gram-positive cocci  
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Escherichia coli category   Enteric gram-negative Bacilli  
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Haemophilus influenza category   Gram-negative Bacilli  
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Pseudomonas category   Gram-negative Bacilli  
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Mycobacterium category   Acid-Fast Bacilli (AFB)  
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Aqueous penicillin G   Natural penicillin, gm+ anaerobes  
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Procain pen G   Natural penicillin, gm+ anaerobes  
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Benzathine pen G   Natural penicillin, gm+ anaerobes  
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Oxacillin   Penicillinase resistant, penicillinase producing gm+ orgs  
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Nafcillin   Penicillinase resistant, penicillinase producing gm+ orgs  
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Dicloxacillin   Penicillinase resistant, penicillinase producing gm+ orgs  
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Cloxacillin   Penicillinase resistant, penicillinase producing gm+ orgs  
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Ampicillin, Ampicillin/sulbactam   Aminopenicillin (Extended Spectrum), same gm+ as pen G, some gm- (E. coli, H. flu)  
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Amoxicillin, Amoxicillin/clavulanate   Aminopenicillin (Extended Spectrum) Same gm- as pen G, some gm- (E. coli, H. flu)  
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Carbenicillin   Antipseudomonal Penicillin, pseudomonas  
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Ticarcillin   Antipseudomonal Penicillin, pseudomonas  
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Piperacillin, Piperacillin/tazobactam   Antipseudomonal Penicillin, pseudomonas  
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Cephalexin   Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis  
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Cephradine   Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis  
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Cefadroxil   Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis  
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Cefaclor   Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu)  
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Cefuroxime axetil   Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu)  
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Cefprozil   Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu)  
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Loracarbef   Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu)  
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Cefixime   Cephalosporins-3rd gen, more gm-, less gm+, moderate against pseudomonas  
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Cefpodoxime   Cephalosporins-3rd gen, more gm-, less gm+, moderate against pseudomonas  
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Ciprofloxacin   Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella  
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Ofloxacin   Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella  
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Lomefloxacin   Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella  
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Trovafloxacin   Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella  
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Gatifloxacin   Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella  
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Erythromycin   Macrolides, gm+, gm- (H. flu), genital pathogens  
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Clarithromycin   Macrolides, gm+, gm- (H. flu), genital pathogens  
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Azithromycin   Macrolides, gm+, gm- (H. flu), genital pathogens  
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Tetracycline   Tetracyclines, gm+, gm-, acne  
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Metronidazole (Flagyl)   Misc, gm+ and gm- anaerobes  
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Clindamycin   Misc, gm+ and gm- aerobes and anaerobes (better than Flagyl against), protozoa  
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SMX-TMP   Misc, gm+ and gm- aerobes, chlamydia, protozoa, UTI & PCP infections  
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Imipenem/cilastin   Carbapenems, wide spectrum, powerful  
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Aztreonam   Monobactams, powerful gm-, high resistance  
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Vancomycin   Glycopeptides, powerful gm+, high resistance  
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Teicoplanin   Glycopeptides, powerful gm+, MRSA  
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Gentamicin   Aminoglycosides, powerful gm-, low resistance  
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Tobramycin   Aminoglycosides, powerful gm-, low resistance  
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Gentamicin & Tobramycin (Aminoglycosides) toxicity   otoxicity, nephrotoxicty  
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Natural Penicillins Spectrum   Gm+ anaerobes  
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Penicillinase resistant spectrum   penicillinase producing gm+  
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Amonopenicillin (Extended Spectrum) spectrum   Same Gm+ as pen G, Gm- (salmonella, shigella, some E. coli, & H. flu)  
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Antipseudomonal Penicillin spectrum   Pseudomonas (gm-)  
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Cephalosporins-1st gen spectrum   gm+, little gm-, no H. flu, no B. fragillis  
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Cephalosporins-2nd gen spectrum   same gm+, addit gm- (H. flu)  
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Cephalosporins-3rd gen spectrum   gm-, less gm+, moderate against pesudomonas  
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Fluoroquinolones spectrum   excellent gm- (H. flu), decent gm+, shigella, salmonella  
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Macrolides spectrum   gm+, gm- (H. flu), genital pathogens, others: MAC, legionella, mycoplasma pneumonia, helicobacter pylori  
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Tetracyclines spectrum   decent gm+ and gm-, acne  
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Metronidazole spectrum   gm+ and gm- anaerobes  
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Clindamycin spectrum   gm+ and gm- anaerobes (better) and aerobes, protozoa  
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SMX-TMP spectrum   gm+ and gm- aerobes, chlamydia, protozoa, *UTIs, PCP*  
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Carbapenems/Imipenem/cilastin spectrum   wide, powerful, high resistance  
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Monobactams/Aztreonam spectrum   powerful gm-, high resistance  
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Glycopeptides/Vancomycin & Teicoplanin spectrum   powerful gm+, MRSA  
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Aminoglycosides/Gentamicin & Tobramycin spectrum   powerful gm-, low resistance  
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Oxacillin, Nafcillin, Dicloxacillin, Cloxacillin   Penicillinase resistant, penicillinase producing gm+ orgs  
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Ampicillin, Amoxicillin   Aminopenicillin, gm+ and gm- (more gm-)  
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Carbenicillin, Ticarcillin, Piperacillin   Antipseudomonal Penicillins  
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Cephalexin, Cephradine, Cefradoxil   1st gen Cephalosporins, gm+. little gm-, no H. flu, no B. fragilis  
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Cefaclor, Cefuroxime axetil, Cefprozil, Loracarbef   Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu)  
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Cefixime, Cefpodoxime   Cephalosporins-3rd gen, gm-, less gm+  
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Imipenem/cilastin   Carbapenem  
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Axtrepnam   Monobactam, gm-  
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Vancomycin, Teicoplanin   Glycopeptides, gm+, MRSA  
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Gentamicin, Tobramycin   Aminoglycosides, gm-  
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