Duke PA pathology
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Which mechanisms of disease caused by tumors cause pain? | tissue destruction, organ compression
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| Staging catergorizes malignant tumors based on what? | potential for invasion and metastasis
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| Tumor grading is based on what? | histologic examination of the tumor, provides estimated degree of malignancy
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| TMN system | tumor staging
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| T in TMN system | reflects size of tumor
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| N in TMN system | reflects lymph node involvement
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| M in TMN system | reflects the extent of metastasis
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| In tumor staging, which number indicates a better prognosis? | lower
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| Who performs tumor grading? | pathologist
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| Is grading system the same for all tumors? | no - differs according to tumor type
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| Grade I tumor | well-differentiated, low anaplasia
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| Grade II, III tumor | intermediate differentiation
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| Grade IV tumor | poorly differentiated; high anaplasia
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| Major therapeutic modalities for cancer | surgery, radiation, chemo, immunotherapy, molecularly-based therapy, combination therapy
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| What is the 3rd most common cancer in incidence and mortality? | colorectal cancer
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| What percent of colorectal cancer has hereditary component? | 15-50 percent
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| What percent of colorectal cancer is due to known mutations? | roughly 15 percent - FAP, HNPCC
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| Can tobacco cause colon cancer? | yes
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