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ZELMAN Human Diseases 6th ed

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Question
Answer
What are the 3 stages of cancer devolopment in chronological order?   Initiation, Promotion and Progression  
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Why are cancer cells sensitive to radiation therapy and chemotherapy?   Because cancer cells are dividing all the time  
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How often should women have breast self-exams?   once a month  
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What is the normal sex chromosome of a normal male?   XY  
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How many chromosomes do humans have?   46  
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Why do sex-linked diseases affect men more than women?   Because they have an X chromosome  
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What are two colors that color blind people cannot distinguish?   Red and Green  
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What facilitates blood clotting?   Vitamin K  
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What occurs with the deficiency or toxicity of potassium?   cardiac arrest  
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Do benign tumors metastasize?   No  
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What are examples of carcinogens?   cigarettes, asbestos  
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What is a risk factor for some types of cancers?   environment  
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Cancer is the 2nd most common cause of death in the US.   true  
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What contributes to the integrity of mucous membranes?   Vitamin A  
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What happens when children are weaned too quickly from breast milk?   Kwashiorkor  
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Does the lack of calcium cause goiter   No  
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What does DNA contain?   genetic information  
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When does the incidence of Down syndrome increase?   with the mother's age  
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Turner's Syndrome   one of the sex chromosomes is missing resulting in karyotype of 45, XO, indicating the presence of 45 chromosomes, with only one X chromosome.  
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A person should apply sunscreen of at least   15 spf  
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What stands as a warning sign of cancer?   caution  
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Biopsy is   surgical removal and examination under a microscope.  
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What is nightblindness caused by?   A lack of Vitamin A  
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What does lack of Vitamin D in adults result in?   osteomalacia  
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What are bleeding gums cause by?   a lack of Vitamin C  
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What is weak muscle a sign of?   Vitamin D deficiency  
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What are congenital diseases?   those appearing @ birth or shortly after  
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What is an example of a familial disease?   Diabetes  
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What % chance does a female carrier of a sex-linked trait have of transmitting it to her offspring?   50%  
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adenoma   benign tumor of a gland  
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neoplasm   mass of cells that grow more rapidly that normal cells  
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promotion   altered cells that proliferate and bear a resemblance to benign neoplasms  
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chromosomes   DNA assembled into these units  
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hermaphrodite   individuals who have both testes and ovaries  
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amniocentesis   small amount of smniotic fluid that is withdrawn for testing  
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scurvy   disease due to Vitamin C deficiency  
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hypercalcemia   excessive Vitamin D  
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osteomalacia   bone disease in adults caused by lack of Vitamin D; softening of the bones  
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rickets   deficient bones in children that develops when Vitamin D is deficient and can be devoloped by diet  
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hemophiliac   person who blees for long periods of time  
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cyst   sac or capsule containing fluid, usually harmless  
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sarcoma   highly malignant connective tissue tumors  
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____cancer is the most lethal of all gynecological cancers.   ovarian  
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Cancer cells develop from normal cells throught a complex process called____.   transformation  
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Direct visualization techniques or____are used to assess specific locations and to obtain a tissue biopsy.   endoscopy  
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A benign tumor on a gland or____can stimulate oversecretion of a hormone in the structure from which it develops   adenoma  
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____cell carcinomas appear on skin that is visibly damaged as rough, flaky, red scales, with or without ulceration.   squamous  
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____are malignant neoplasms derived from pigment producing cells   melanomas  
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____are benign brain tumors that occur in the membranes that surroung the brain.   meningiomas  
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____is the second phase of malignant transformation whereby initiated cells proliferate and resemble benign neoplasms.   promotion  
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A____or tumor is a mass of cells that grow more rapidly that normal cells.   neoplasm  
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____is the systemic administration of medications to kill tumor cells   chemotherapy  
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Cancer signs and symptoms are often mistaken for signs of other, less-threatening diseases   True  
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Tobacco use is a major preventable cause of disease and premature death in the U.S.   True  
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Malignant tumors do not recur after removal   False benign tumors  
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At least 1/3 of all cancers can be attributed to living habits and carcinogens in the environment   True  
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Lipomas occur more often in men than in women.   False women do  
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A nagging cough or hoarseness can be a non-specific warning sign of cancer   true  
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a malignant neoplsm is usually localized to a tissue or organ   false a benign neoplasm  
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Adenocarcinoma is the most common type of lung cancer that occurs in nonsmokers   true  
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Tumor of the muscle   myoma  
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bloody sputum   heomoptysis  
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cancers of blood forming tissue   leukemia  
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used to detect breast cancer   mammography  
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a change in genetic material prepares the cell to become cancerous   initiation  
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swallowing difficulties   dysphagia  
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cancer cachexia   nutritional wasting  
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non-cancerous   benign neoplasm  
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tumor marker measured in blood   PSA  
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highly malignant connective tissue tumors that originate muscle, fat, bone, and blood vessels   sarcoma  
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The allele for color blindness is on the__chromosome.   X  
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Some alleles always produce an effect and are said to be____.   dominant  
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____is a multi-systemic disease resulting from the dysfunction of the gene that codes for the connective tissue protein fibrillin   Marfan syndrome  
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____involves removing cells from the villi through the cervix.   Chronic Billus Sampling  
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DNA is assembled into units called____.   chromosomes  
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In____the person's sex chromosomes are XXY.   Klinefelter's Syndrome  
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____is identified by a break, or weakness, on the long arm of the X chromosome.   Fragile X syndrome  
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____are alternate forms of a gene.   Alleles  
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____is the failure of two chromosomes to separate as the gametes, either the egg or the sperm, are beign formed.   Nondisjunction  
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Familial hypercholesterolemia is a common cause of cardiovascular disease in the U.S.   True  
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A female may have the sex-linked disease if she is homozygous for the recessive gene.   True  
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There are no treatments available for the hereditary diseases   False  
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Sickle cell anemia is an autosomal recessive disorder   True  
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Autosomes determine gender   False  
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People with hemophilia do not bleed more profusely or bleed faster than normal; they bleed for a longer period of time   True  
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If one parent is normal for a particular condition, each child has a 50% chance of being affected and manifesting the genetic defect   True  
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Sex cells divide by a process called mitosis   False  
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Phenylketonuria is caused by an autosomal dominant allele   False  
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Alleles that always produce an effect are said to be dominant   True  
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Only manifest themselves when the person is homozygous for the trait   recessive allele  
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An enzyme deficiency cause abnormal lipid metabolism in the brain, which results in progressive mental and physical retardation   Tay-sachs  
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Extra fingers or toes   polydactyly  
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XO karyotype   Turner's Syndrome  
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Identical alleles   homozygous  
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Diseases manifest theselves only when a person is homozygous for the defective allele   Autosomal recessive diseases  
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cartilage formation in the fetus is defective   achondroplasia  
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lack the enzyme necessary to convert galactose, a sugar derived from lactose in milk, to glucose   galactosemia  
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different alleles   heterozygous  
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a deletion of part of the short arm of choromosome 5   Cri du chat syndrome  
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___is the most common nutritional deficiency in the world   Iron Deficiency Anemia  
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Nearly___of adult Americans are overwight or obes despite published recommendation for healthy eating and healthy lifestyles   1/3  
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____works with calcium to support bone and tooth formation, nerve conduction, and muscle contractions   magnesium  
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____is required for absorption of clalcium and phosphorus from the gastrointestinal tract and for mineralization of bone   Vitamin D  
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____are chemical compounds consumed in food that are required for vital cellular processes that ensure growth and development, recovery from illness, and prevention of chronic disease   Nutrients  
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___are inorganic metals that do not furnish energy   minerals  
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Dietary vitamin C is required to prevent and to treat____   scurvy  
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____is caused by inadequate intake of carbohydrates, fats, proteins, minerals, and water   PEM (Protein Energy Malnutrition)  
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____, though not an esssential mineral, is necessary for the prevention of dental carries   Fluorine  
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There are approximately___nutrients that are required by the human body   40  
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More that 300 candidate genes have been identified that influence obesity in humans   True  
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In acute fluorine toxicity, irrecular chalky withe patches occur on the surface of the teeth   True  
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The primary manifestation of vitamin E deficiency is hemolytic anemia   true  
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obesity is the leadiing preventable cause of death among adults in the U.S.   False  
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Excess calcium is excreted through the bile produced by the liver   false  
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vitamin K deficiency is common in adults   false  
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Health care costs associated with obesity amount to nearly $100 biliion annually within the U.S.   True  
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Most large controlled research studies fail to demonstrate the value of vitamin C in the treatment or prevention of the common cold   True  
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the thyroid gland stores about 80% of the iodide that is ingested   True  
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Children raised in families with one overweight parent have a 80% chance of becoming overweight as an adult.   False  
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Can be syntehsized from the amino acid tryptophan   Niacin  
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Vitamin D deficiency in children   Rickets  
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Organic compounds that have important functions in metabolic reations that result in the release or storage of energy from carbohydrates, fats, and proteins   Vitamins  
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Functions as a coenzyme in gas exchange and in fat and carbohydrate metabolism   Biotin  
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Antioxidant protects tissues against free radicals   Vitamin C  
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Required for synthesis of coagulation factors within the liver   Vitamin K  
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Serves as a component in protein, lipid, and carbohydrate metabolism and fro red blood cell synthesis   Folic Acid  
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Inorganic elements that do not provide energy, but are needed for a number of anabolic and catabolic biochemical reactions within the body   Minerals  
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An important regulator for muscle activity and transmission of nerve impulses   Potassium  
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Combines with opsin to form rhodopsin, a pigment receptor that absorbs light in the rods of the retina in the eye   Vitamin A  
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