respiratory
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| adrenergic agents- constrict small arteriolestaht supply the structures of the upperrespiratotory tract. | nonopiod antitussive | cough reflex stimulation or direct stimulation of the secretory glands in the repiraotyr tract. | EXPECTORANT | xanthine and beta agonists | bronchodialation by increasing the levles of energy producing substance cAMP | xanthine
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| contraindicated in pts with diabetes, hypertension, cardiac disease, throid dysfunction | nonaddiction and does not cause CNS depression | used for productive cough | thins difficult to cough up mucus in respiratory tract. | increase level of cAMP by inhibiting enzyme that breaks down cAMP = alveolar stay open | caffiene | tx of chronic respiratory disorders ; relief of mild to moderate acute
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| constric sm artioles; anticholinergic; cortocosteriods- rarely used -aimed at inflammatory repsonse | Adverse effects Respiratory: Respiratory depression (with overdose) | MOA- 1.) reflex of stimulation by loosening and thinning rspt secretions 2.)dirct stimulation of secrtory glands | Adverse effects CNS: Headache, dizziness Dermatologic: Rash, urticaria GI: Nausea, vomiting, GI discomfort | tx for dmphaysem and chronic bronchitis | relatively slow onset- used for prevention of asthma attacks | increased metabolization in liver = incrased interactis and toxitiy
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| 3 routes- 1.)intranasally, 2.)orally, 3.topically | Lacks analgesic and addictive properties; controls cough spasms by depressing the cough center in the medulla; analog of codeine. | cough reflex stimulation or direct stimulation of the secretory glands in the repiraotyr tract. | Indications Symptomatic relief of respiratory conditions characterized by dry, nonproductive cough and in the presence of mucus in the respiratory tract. | SE- nauses, vomitting, anorexia, GE reflux | SE- nauses, vomitting, anorexia, GE reflux | blood levels10-20 mcg/ml
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