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Ativan,Atropine,Activated charcoal, Dopamine, Oxytocin

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Question
Answer
Activated charcoal GENERIC NAME   None  
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Activated charcoal BRAND NAME   Activated charcoal  
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Activated charcoal CLASS   Adsorbent  
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Activated charcoal MECHANISM OF ACTION   Adsorbs toxic substances from the GI tract.  
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Activated charcoal INDICATIONS   Most oral poisonings and medication overdoses.  
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Activated charcoal CONTRAINDICATIONS   AMS, ingestion of corrosives, caustics, or petroleum distillates.  
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Activated charcoal ADVERSE REACTIONS   May induce N/V.  
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Activated charcoal NOTES ON ADMINISTRATION   Will not adsorb cyanide, lithium, iron, lead, or arsenic.  
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Activated charcoal INCOMPATABILITIES/DRUG INTERACTIONS   Bonds with and generally inactivates anything it is administered with.  
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Activated charcoal DOSE/ROUTE Adult and peds   1-2g/kg PO or NGT.  
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Activated charcoal ONSET OF ACTION   Variable  
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Activated charcoal PEAK EFFECTS   n/a  
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Activated charcoal DURATION OF ACTION   Variable  
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Activated charcoal AZ DRUG BOX SUPPLY RANGE   50g  
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Atropine GENERIC NAME   None  
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Atropine BRAND NAME   Atropine  
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Atropine CLASS   Anticholinergic agent  
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Atropine MECHANISM OF ACTION   Parasympatholytic. Increases HR in life threatening bradyarrhythmias.  
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Atropine INDICATIONS   Hemodynamically unstable Bradycardia, Asystole, Bradycardic PEA, Organophosphate poisoning.  
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Atropine CONTRAINDICATIONS   Tachycardia, Hypersensitivity, MI, narrow-angle glaucoma.  
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Atropine ADVERSE REACTIONS   HA, dizziness, Palpitations, Tachycardia, arrhythmias, paradoxical Bradycardia when pushed slowly or at low doses, flushed, hot, dry skin, N/V.  
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Atropine NOTES ON ADMINISTRATION   Moderate doses may cause pupil dilation.  
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Atropine INCOMPATABILITIES/DRUG INTERACTIONS   Potential adverse effects when administered with digoxin, cholinergics, physostigmine.  
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Atropine DOSE/ROUTE ADULT Asystole and Bradycardic PEA   1mg IV/IO push may repeat every 3-5 minutes up to 3 doses.  
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Atropine DOSE/ROUTE ADULT Unstable Bradycardia   0.5 mg IV/IO every 3-5 minutes not to exceed 3mg total.  
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Atropine DOSE/ROUTE ADULT Organophosphate Poisoning   Extremely large doses (2-4mg or higher)  
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Atropine DOSE/ROUTE PEDEATRIC   0.02 mg/kg IV/IO push. May double for second dose. Minimum single dose is 0.1 mg. Maximum single dose in child is 0.5mg. Child total dose, 1mg.  
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Atropine ONSET OF ACTION   Immediate  
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Atropine PEAK EFFECTS   Rapid to 1-2 minutes  
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Atropine DURATION OF ACTION   6 hours  
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Atropine AZ DRUG BOX SUPPLY RANGE   (4) prefilled 1mg syringes. Total 4mg. (1) 8mg Multidose vial.  
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Oxytocin GENERIC NAME   Oxytocin  
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Oxytocin BRAND NAME   Pitocin  
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Oxytocin CLASS   Hormone  
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Oxytocin MECHANISM OF ACTION   Increases uterine contractions  
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Oxytocin INDICATIONS   Postpartum hemorrhage after infant and placental delivery.  
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Oxytocin CONTRAINDICATIONS   Presence of 2nd fetus. Unfavorable fetal position, hypersensitivity.  
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Oxytocin ADVERSE REACTIONS   Hypotension, hypertension, tachycardia, arrhythmias, angina, anxiety, sz, N/V, uterine rupture.  
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Oxytocin NOTES ON ADMINISTRATION   Monitor vital signs and uterine tone closely.  
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Oxytocin INCOMPATABILITIES/DRUG INTERACTIONS   Other vasopressors might potentiate hypertension.  
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Oxytocin DOSE/ROUTE After delivery of placenta IM   3-10 units.  
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Oxytocin DOSE/ROUTE After delivery of placenta IV   Mix 10-40 units in 1000cc of NS.  
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Oxytocin ONSET OF ACTION   IM 5 minutes. IV immediate  
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Oxytocin PEAK EFFECTS   Variable  
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Oxytocin DURATION OF ACTION   IM 60 minutes, IV 20 minutes  
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Oxytocin AZ DRUG BOX SUPPLY RANGE   10 units optional  
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Lorazepam GENERIC NAME   Lorazepam  
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Lorazepam BRAND NAME   Ativan  
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Lorazepam CLASS   Benzodiazepine, Anticonvulsive  
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Lorazepam MECHANISM OF ACTION   Anxiolytic, anticonvulsant, and sedative effects, by binding with benzodiazepine receptors and enhancing the effects of GABA.  
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Lorazepam INDICATIONS   Initial control of status epilepticus or severe recurrent seizures, severe anxiety, sedation.  
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Lorazepam CONTRAINDICATIONS   Acute narrow angle glaucoma. Coma, shock, or suspected drug abuse.  
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Lorazepam ADVERSE REACTIONS   apnea, drowsiness, sedation, ataxia, psychomotor impairment, confusion, restlessness, hypotension, Bradycardia.  
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Lorazepam NOTES ON ADMINISTRATION   Inadvertent arterial injection may result in vasospasm and gangrene.  
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Lorazepam INCOMPATABILITIES/DRUG INTERACTIONS   May precipitate CNS depression if patient already on CNS depressant medications.  
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Lorazepam DOSE/ROUTE Adult   2-4mg slow IV or IM. May repeat in 15-20 minutes to a max of 8mg.  
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Lorazepam DOSE/ROUTE Pediatric   0.05-0.20 mg/kg slow IV/IO over 2 minutes or IM. May repeat in 15-20 minutes to a max dose of 0.2 mg/kg  
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Lorazepam ONSET OF ACTION   5 minutes  
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Lorazepam PEAK EFFECTS   Variable  
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Lorazepam DURATION OF ACTION   8 hours  
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Lorazepam AZ DRUG BOX SUPPLY RANGE   8mg optional  
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Dopamine GENERIC NAME   Dopamine  
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Dopamine BRAND NAME   Intropin  
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Dopamine CLASS   Sympathomimetic, inotropic agent  
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Dopamine MECHANISM OF ACTION   Stimulates alpha and beta adrenergic receptors. Increases myocardial contractility and stroke volume. Increases SVR.  
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Dopamine INDICATIONS   hypotension with low cardiac output states.  
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Dopamine CONTRAINDICATIONS   Hypovolemic shock, v-tach, v-fib  
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Dopamine ADVERSE REACTIONS   Tachycardia, arrhythmias, angina, dyspnea, ha, n/v, skin and soft tissue necrosis,  
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Dopamine NOTES ON ADMINISTRATION   Pregnancy safety not established.  
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Dopamine INCOMPATABILITIES/DRUG INTERACTIONS   MAOI’s will enhance effects. Beta blockers may antagonize effects.  
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Dopamine DOSE/ROUTE ADULT and PEDS   2-20 mcg/kg/min titrated to patient response  
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Dopamine ONSET OF ACTION   4 minutes  
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Dopamine PEAK EFFECTS   10 minutes  
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Dopamine DURATION OF ACTION   Stops immediately after DC  
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Dopamine AZ DRUG BOX SUPPLY RANGE   400mg  
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