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Drug profiles

Ativan,Atropine,Activated charcoal, Dopamine, Oxytocin

QuestionAnswer
Activated charcoal GENERIC NAME None
Activated charcoal BRAND NAME Activated charcoal
Activated charcoal CLASS Adsorbent
Activated charcoal MECHANISM OF ACTION Adsorbs toxic substances from the GI tract.
Activated charcoal INDICATIONS Most oral poisonings and medication overdoses.
Activated charcoal CONTRAINDICATIONS AMS, ingestion of corrosives, caustics, or petroleum distillates.
Activated charcoal ADVERSE REACTIONS May induce N/V.
Activated charcoal NOTES ON ADMINISTRATION Will not adsorb cyanide, lithium, iron, lead, or arsenic.
Activated charcoal INCOMPATABILITIES/DRUG INTERACTIONS Bonds with and generally inactivates anything it is administered with.
Activated charcoal DOSE/ROUTE Adult and peds 1-2g/kg PO or NGT.
Activated charcoal ONSET OF ACTION Variable
Activated charcoal PEAK EFFECTS n/a
Activated charcoal DURATION OF ACTION Variable
Activated charcoal AZ DRUG BOX SUPPLY RANGE 50g
Atropine GENERIC NAME None
Atropine BRAND NAME Atropine
Atropine CLASS Anticholinergic agent
Atropine MECHANISM OF ACTION Parasympatholytic. Increases HR in life threatening bradyarrhythmias.
Atropine INDICATIONS Hemodynamically unstable Bradycardia, Asystole, Bradycardic PEA, Organophosphate poisoning.
Atropine CONTRAINDICATIONS Tachycardia, Hypersensitivity, MI, narrow-angle glaucoma.
Atropine ADVERSE REACTIONS HA, dizziness, Palpitations, Tachycardia, arrhythmias, paradoxical Bradycardia when pushed slowly or at low doses, flushed, hot, dry skin, N/V.
Atropine NOTES ON ADMINISTRATION Moderate doses may cause pupil dilation.
Atropine INCOMPATABILITIES/DRUG INTERACTIONS Potential adverse effects when administered with digoxin, cholinergics, physostigmine.
Atropine DOSE/ROUTE ADULT Asystole and Bradycardic PEA 1mg IV/IO push may repeat every 3-5 minutes up to 3 doses.
Atropine DOSE/ROUTE ADULT Unstable Bradycardia 0.5 mg IV/IO every 3-5 minutes not to exceed 3mg total.
Atropine DOSE/ROUTE ADULT Organophosphate Poisoning Extremely large doses (2-4mg or higher)
Atropine DOSE/ROUTE PEDEATRIC 0.02 mg/kg IV/IO push. May double for second dose. Minimum single dose is 0.1 mg. Maximum single dose in child is 0.5mg. Child total dose, 1mg.
Atropine ONSET OF ACTION Immediate
Atropine PEAK EFFECTS Rapid to 1-2 minutes
Atropine DURATION OF ACTION 6 hours
Atropine AZ DRUG BOX SUPPLY RANGE (4) prefilled 1mg syringes. Total 4mg. (1) 8mg Multidose vial.
Oxytocin GENERIC NAME Oxytocin
Oxytocin BRAND NAME Pitocin
Oxytocin CLASS Hormone
Oxytocin MECHANISM OF ACTION Increases uterine contractions
Oxytocin INDICATIONS Postpartum hemorrhage after infant and placental delivery.
Oxytocin CONTRAINDICATIONS Presence of 2nd fetus. Unfavorable fetal position, hypersensitivity.
Oxytocin ADVERSE REACTIONS Hypotension, hypertension, tachycardia, arrhythmias, angina, anxiety, sz, N/V, uterine rupture.
Oxytocin NOTES ON ADMINISTRATION Monitor vital signs and uterine tone closely.
Oxytocin INCOMPATABILITIES/DRUG INTERACTIONS Other vasopressors might potentiate hypertension.
Oxytocin DOSE/ROUTE After delivery of placenta IM 3-10 units.
Oxytocin DOSE/ROUTE After delivery of placenta IV Mix 10-40 units in 1000cc of NS.
Oxytocin ONSET OF ACTION IM 5 minutes. IV immediate
Oxytocin PEAK EFFECTS Variable
Oxytocin DURATION OF ACTION IM 60 minutes, IV 20 minutes
Oxytocin AZ DRUG BOX SUPPLY RANGE 10 units optional
Lorazepam GENERIC NAME Lorazepam
Lorazepam BRAND NAME Ativan
Lorazepam CLASS Benzodiazepine, Anticonvulsive
Lorazepam MECHANISM OF ACTION Anxiolytic, anticonvulsant, and sedative effects, by binding with benzodiazepine receptors and enhancing the effects of GABA.
Lorazepam INDICATIONS Initial control of status epilepticus or severe recurrent seizures, severe anxiety, sedation.
Lorazepam CONTRAINDICATIONS Acute narrow angle glaucoma. Coma, shock, or suspected drug abuse.
Lorazepam ADVERSE REACTIONS apnea, drowsiness, sedation, ataxia, psychomotor impairment, confusion, restlessness, hypotension, Bradycardia.
Lorazepam NOTES ON ADMINISTRATION Inadvertent arterial injection may result in vasospasm and gangrene.
Lorazepam INCOMPATABILITIES/DRUG INTERACTIONS May precipitate CNS depression if patient already on CNS depressant medications.
Lorazepam DOSE/ROUTE Adult 2-4mg slow IV or IM. May repeat in 15-20 minutes to a max of 8mg.
Lorazepam DOSE/ROUTE Pediatric 0.05-0.20 mg/kg slow IV/IO over 2 minutes or IM. May repeat in 15-20 minutes to a max dose of 0.2 mg/kg
Lorazepam ONSET OF ACTION 5 minutes
Lorazepam PEAK EFFECTS Variable
Lorazepam DURATION OF ACTION 8 hours
Lorazepam AZ DRUG BOX SUPPLY RANGE 8mg optional
Dopamine GENERIC NAME Dopamine
Dopamine BRAND NAME Intropin
Dopamine CLASS Sympathomimetic, inotropic agent
Dopamine MECHANISM OF ACTION Stimulates alpha and beta adrenergic receptors. Increases myocardial contractility and stroke volume. Increases SVR.
Dopamine INDICATIONS hypotension with low cardiac output states.
Dopamine CONTRAINDICATIONS Hypovolemic shock, v-tach, v-fib
Dopamine ADVERSE REACTIONS Tachycardia, arrhythmias, angina, dyspnea, ha, n/v, skin and soft tissue necrosis,
Dopamine NOTES ON ADMINISTRATION Pregnancy safety not established.
Dopamine INCOMPATABILITIES/DRUG INTERACTIONS MAOI’s will enhance effects. Beta blockers may antagonize effects.
Dopamine DOSE/ROUTE ADULT and PEDS 2-20 mcg/kg/min titrated to patient response
Dopamine ONSET OF ACTION 4 minutes
Dopamine PEAK EFFECTS 10 minutes
Dopamine DURATION OF ACTION Stops immediately after DC
Dopamine AZ DRUG BOX SUPPLY RANGE 400mg
Created by: klindley
 

 



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