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Vocab Review

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Term
Definition
agonists   Drugs that activate receptors to accelerate or slow normal cellular function.  
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antagonists   Drugs that bind with receptors but don't activate them. They block receptor action by preventing other drugs or substances from activating with them.  
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receptor   The cellular material located at the site of the action that interacts with the drug.  
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site of action   The location where an administered drug produces an effect.  
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hydrophilic   Capable of associating w/ or absorbing water.  
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hydrophobic   Water repelling; can't associate with water.  
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half-life   Amount of time it takes for the blood concentration of a drug to decline to one-half of an initial value.  
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absorption   The movement of a drug from the dosage formulation into the blood.  
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bioavailability   The amount of an administered dose that reaches the general circulation and the rate at which this occurs.  
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bioequivalency   The comparison of bioavailability b/w two dosage forms.  
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pharmaceutical equivalent   Drug products that contain identical amounts of the same active ingredient in the same dosage form.  
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therapeutic equivalent   Pharmaceutical equivalents that produce the same effects in patients.  
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Orange Book   Provides info on the therapeutic equivalence of brand and generic drugs.  
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