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Chapter 11
Vocab Review
Term | Definition |
---|---|
agonists | Drugs that activate receptors to accelerate or slow normal cellular function. |
antagonists | Drugs that bind with receptors but don't activate them. They block receptor action by preventing other drugs or substances from activating with them. |
receptor | The cellular material located at the site of the action that interacts with the drug. |
site of action | The location where an administered drug produces an effect. |
hydrophilic | Capable of associating w/ or absorbing water. |
hydrophobic | Water repelling; can't associate with water. |
half-life | Amount of time it takes for the blood concentration of a drug to decline to one-half of an initial value. |
absorption | The movement of a drug from the dosage formulation into the blood. |
bioavailability | The amount of an administered dose that reaches the general circulation and the rate at which this occurs. |
bioequivalency | The comparison of bioavailability b/w two dosage forms. |
pharmaceutical equivalent | Drug products that contain identical amounts of the same active ingredient in the same dosage form. |
therapeutic equivalent | Pharmaceutical equivalents that produce the same effects in patients. |
Orange Book | Provides info on the therapeutic equivalence of brand and generic drugs. |