board review for pathology
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Ankylosing spondylitis | autoimmune disease, HLA B-27
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| First group of muscles involved in Duchenne muscular dystrophy? | pelvic girdle
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| Vitamin K deficiency | bruising and bleeding
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| Reiter's syndrome | arthritis, Urthritis, conjunctivitis and skin rash
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| Fissures in articular cartilage and decreased proteoglycan within the matrix | osteoarthritis
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| deficiency of vitamin B12 results in this anemia | megaloblastic anemia
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| Chronic rheumatoid arthritis and splenomegaly | Felty's syndrome
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| Elephantiasis | obstruction of draining lymphatics
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| Multiple myeloma | malignant plasma cells, Bence Jones protein, M spike
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| AIDS | CD4 (T helper cells)
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| Pyogenic osteomyelitis affects which part of the bone | metaphysis
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| most common cause of pyogenic osteomyelitis | Staph. aureus
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| Pathological lesions in basal ganglia | Parkinson, Huntington, Wilson
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| Excess uric acid | gout
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| monosodium ureate crystals | gout, tophi
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| Hashimoto's disease | hypothyroidism, autoimmune
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| Most common malignant bone tumor | metastatic tumors
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| most common primary malignant bone tumors | osteosarcoma
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| Most common location for osteosarcoma | metaphysis of long bones around knee joint
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| Most common benign tumor in the uterus | leiomyoma
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| Type of necrosis most common in CNS | liquefactive
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| Kernicterus | unconjugated hyperbilirubinemia reaching the basal ganglia of infants
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| Accumulation of glucocerebrosides in the cells | Gaucher's disease
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| Both UMNL and LMNL occur in | amyotrophic lateral sclerosis
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| Thiamin deficiency causes | dry and wet beriberi
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| Hemophilia A | deficiency of antihemophilic globulin (factor 8)
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| Hemophilia B | deficiency of Christmas factor (factor 9)
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| Movement of leukocytes in response to concentration gradient of chemokines | chemotaxis
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| Smoking is a major cause of | cancer lung, thromboangitis obliterans, chronic bronchitis
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| Implicated in cancer cervix, vagina, and vulva | Human papilloma virus (types 16 & 18)
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| Signs in Kwashiorkor | edema, flaky-paint skin, retardation of growth, hepatomegaly
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| Marasmus is caused by | deficiency of calories (CHO and lipids)
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| T lymphocyte that helps in function of B lymphocyte | CD4
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| Most important leukocyte in acute inflammation | neutrophils
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| Example of granulomatous inflammation | TB, leprosy, syphilis, Sarcoidosis
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| Lesions in tertiary stage of syphilis | gumma, cardiovascular syphilis (aneurysm, aortic regurge) and neurosyphilis (meningovascular syphilis, paresis, tabes dorsalis)
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| Important factor in the deline of cervical cancer? | routine PAP smears
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| Decreased blood proteins | edema (decreased colloidal OP)
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| Arachnodactayly, subluxation of the lens, cardiac defects and hyperextensibility of the joints, aortic aneurysm | Marfan's syndrome
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| Albers Shoenberg disease | marble bone disease, defective function of osteoclast
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| Clinical features of Parkinson disease is related to | extrapyramidal system (deficiency of dopamine secreted by pigmented neurons in substania nigra of midbrain)
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| Familial hypercholesterolemia is considered as | most common autosomal dominant disease in USA (cholesterol receptors on liver cells)
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| A 25 year old female represents by weakness o extraocular muscles | myasthenia gravis
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| Most common symptom in esophageal cancer | dysphagia
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