Calcium Chloride

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Answer

GENERIC NAME

None

BRAND NAME

Calcium Chloride

CLASS

Electrolyte

MECHANISM OF ACTION

Increases cardiac contractile state (positive inotropic effect), May enhance ventricular automaticity

INDICATIONS

1. Hypoglycemia, 2. Hyperkalemia 3. Magnesium sulfate overdose 4. Calcium channel blocker overdose 5. Adjunctive therapy in treatment of insect bites and stings

CONTRAINDICATIONS

1. Hypercalcemia 2. V-fib 3. Digitalis toxicity

ADVERSE REACTIONS

1. Bradycardia, 2. Asystole. 3. Hypotension 4.Peripheral Vasodilation. 5. Metallic taste. 6. Local necrosis. 7. Coronary and cerebral artery spasm. 8. Nausea and Vomiting.

NOTES ON ADMINISTRATION

Pregnancy safety Category C. Do not use routinely in cardiac arrest.

INCOMPATABILITIES/DRUG INTERACTIONS

May worsen arrhythmias secondary to digitalis toxicity. May antagonize the effects of verapamil. Do not mix with or infuse immediately before or after sodium bicarbonate without intervening flush.

DOSE/ROUTE Adult

500-1000mg (5-10 ml of a 10% solution) IV/IO push for Hyperkalemia and calcium channel blocker overdose. May be repeated as needed. DOSE/ROUTE Pediatric

ONSET OF ACTION

5-15 minutes

PEAK EFFECTS

3-5 minutes.

DURATION OF ACTION

15-30 minutes, but may persist for 4 hours (dose dependent).

AZ DRUG BOX SUPPLY RANGE

1 Gram