Powders 2 - DDS II
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| Rank the following in order of size from smallest to largest: Very fine, Very Coarse, Fine, Coarse, Moderately Coarse. | Very fine, Fine, Moderately coarse, Coarse, and Very coarse
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| Finely and uniformly divided so as to smooth to the touch is a desirable property of ________________. | Powders
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| Define adsorptive. | The adhesion of a thin layer of molecules of some substance to the surface of a solid or liquid.
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| What is the USP terminology for particle size? | Very coarse, coarse, moderately coarse, fine and very fine.
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| Starch is a(n) ___________ and a(n) _________. | Vehicle, adsorbent
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| Minimal stratification when powders are stored or transported is an advantage of ____________. | Uniform particle size
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| What method of powder blending is used when a small amount of potent substance is to be mixed with a large amount of diluent by geometric dilution method. | Trituration
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| Define powder. | Intimate mixtures of dry, finely divided drugs and
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| What are the three categories of particle sizes of powder? | Fine, Colloidal, and Coarse
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| A carbonated solution that masks undesirable taste of a drug is a(n) ___________. | Effervescent
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| What process is used to obtain small doses which are below the minimum weighable quantity? | Trituration
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| Why are some injections reconstituted immediately before use? | They are unstable in solution
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| Define eutectic mixture. | That proportion og components which will give the lowest melting point.
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| Why is a combination of tartaric acid and citric acids used as an effervescent base rather than either acid alone? | Tartaric acids easily crumbles to form a fine powder, and citric acid forms a sticky mass and is difficult to granulate.
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| What types of containers are suitable for dusting powders? | Suitable bulk containers such as wide mouth glass jar, or a perforated or sifter can.
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| Name two common diluents powders for formulation of a bulk powder. | Starch and Talc
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| Name four methods of blending powders. | Spatulation, Trituration, Sifting, and Tumbling
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| What method of powder blending is used when a small amount of powders are blended by the movement of a spatula through the powders on a sheet of paper. | Spatulation
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| What are the two most common bases used to prepare effervescent granules? | Sodium bicarbonate and potassium bicarbonate
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| What type of powder blending results in a light, fluffy product? | Sifting
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| Methyl salicylate is a(n) _____________. | Scent
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| What method is used to comminute hard crystalline substances that do not crush easily? | Pulverization
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| What method of comminution is used to obtain particles of camphor? | Pulverization
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| ___________ were originally designed as a convenient mode of administering hard vegetable drugs such as roots, barks, and woods. | Powders
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| A uniform dissolution rate if the powder is to dissolve is and advantage of _____________. | Uniform particle size
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| Granules are agglomerates of _____________. | Powders
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| In what method of comminution are substances first dissolved in a minimum volume of volatile solvent such as alcohol or acetone? | Pulverization
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| Powders used in dry form include: | Powders for topical application, Dental cleansing powders, Insufflations, Powder from a packet that are mixed in soft foods
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| Rank the following in order of size from largest to smalllest: Very fine, Very Coarse, Fine, Coarse, Moderately Coarse. | Very coarse, Coarse, Moderately coarse, Fine and Very fine.
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| Talc is a(n) ___________ and a(n) _________. | Vehicle, adsorbent
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| What are dentifrices? | Powders used to clean the teeth.
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| What method of powder blending are used when powders are mixed in a rotating container. | Tumbling
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| Name three methods of comminution. | Trituration, Levigation, Pulverization
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| How are trituration and comminution related? | Trituration is a form of comminution in which continued rubbing of a solid in a mortar and pestle is used to reduce the solid particles to a desirable degree of fineness.
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| What is the continued rubbing of a solid in a mortar called? | Trituration
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| Which is more stable, a liquid or a powder? | Powder
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| Powders that are reconstituted include: | Oral antibiotic, Powders for injection
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| What is used in a community pharmacy to comminute particle size? | Mortar and pestle
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| What are two common levigating agents? | Mineral oil and Glycerin
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| Addition of what prevents liquefaction due to the formation of an eutectic mixture? | Magnesium carbonate or sialic acid
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| Talc is often used as a ________ or ___________. | Lubricant or astringent
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| Benzocaine is a(n) _____________. | Local anesthetic
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| Grinding of powder with the help of a liquid is known as ____________. | Levigation
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| What method of comminution is used when working with hard, fracturable powders? | Trituration
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| What is the simplest dosage form? | Powder
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| Finely divided powders intended for application to body cavities are called ___________. | Insufflations
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| How are hygroscopic substance supplied in order to avoid exposure to the air? | In granular form and double wrapped.
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| Substances which absorb moisture from the air are called __________. | Hygroscopic
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| Powders were originally designed as a convenient mode of administering __________. | Hard vegetable drugs
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