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Powders 2

Powders 2 - DDS II

QuestionAnswer
Rank the following in order of size from smallest to largest: Very fine, Very Coarse, Fine, Coarse, Moderately Coarse. Very fine, Fine, Moderately coarse, Coarse, and Very coarse
Finely and uniformly divided so as to smooth to the touch is a desirable property of ________________. Powders
Define adsorptive. The adhesion of a thin layer of molecules of some substance to the surface of a solid or liquid.
What is the USP terminology for particle size? Very coarse, coarse, moderately coarse, fine and very fine.
Starch is a(n) ___________ and a(n) _________. Vehicle, adsorbent
Minimal stratification when powders are stored or transported is an advantage of ____________. Uniform particle size
What method of powder blending is used when a small amount of potent substance is to be mixed with a large amount of diluent by geometric dilution method. Trituration
Define powder. Intimate mixtures of dry, finely divided drugs and
What are the three categories of particle sizes of powder? Fine, Colloidal, and Coarse
A carbonated solution that masks undesirable taste of a drug is a(n) ___________. Effervescent
What process is used to obtain small doses which are below the minimum weighable quantity? Trituration
Why are some injections reconstituted immediately before use? They are unstable in solution
Define eutectic mixture. That proportion og components which will give the lowest melting point.
Why is a combination of tartaric acid and citric acids used as an effervescent base rather than either acid alone? Tartaric acids easily crumbles to form a fine powder, and citric acid forms a sticky mass and is difficult to granulate.
What types of containers are suitable for dusting powders? Suitable bulk containers such as wide mouth glass jar, or a perforated or sifter can.
Name two common diluents powders for formulation of a bulk powder. Starch and Talc
Name four methods of blending powders. Spatulation, Trituration, Sifting, and Tumbling
What method of powder blending is used when a small amount of powders are blended by the movement of a spatula through the powders on a sheet of paper. Spatulation
What are the two most common bases used to prepare effervescent granules? Sodium bicarbonate and potassium bicarbonate
What type of powder blending results in a light, fluffy product? Sifting
Methyl salicylate is a(n) _____________. Scent
What method is used to comminute hard crystalline substances that do not crush easily? Pulverization
What method of comminution is used to obtain particles of camphor? Pulverization
___________ were originally designed as a convenient mode of administering hard vegetable drugs such as roots, barks, and woods. Powders
A uniform dissolution rate if the powder is to dissolve is and advantage of _____________. Uniform particle size
Granules are agglomerates of _____________. Powders
In what method of comminution are substances first dissolved in a minimum volume of volatile solvent such as alcohol or acetone? Pulverization
Powders used in dry form include: Powders for topical application, Dental cleansing powders, Insufflations, Powder from a packet that are mixed in soft foods
Rank the following in order of size from largest to smalllest: Very fine, Very Coarse, Fine, Coarse, Moderately Coarse. Very coarse, Coarse, Moderately coarse, Fine and Very fine.
Talc is a(n) ___________ and a(n) _________. Vehicle, adsorbent
What are dentifrices? Powders used to clean the teeth.
What method of powder blending are used when powders are mixed in a rotating container. Tumbling
Name three methods of comminution. Trituration, Levigation, Pulverization
How are trituration and comminution related? Trituration is a form of comminution in which continued rubbing of a solid in a mortar and pestle is used to reduce the solid particles to a desirable degree of fineness.
What is the continued rubbing of a solid in a mortar called? Trituration
Which is more stable, a liquid or a powder? Powder
Powders that are reconstituted include: Oral antibiotic, Powders for injection
What is used in a community pharmacy to comminute particle size? Mortar and pestle
What are two common levigating agents? Mineral oil and Glycerin
Addition of what prevents liquefaction due to the formation of an eutectic mixture? Magnesium carbonate or sialic acid
Talc is often used as a ________ or ___________. Lubricant or astringent
Benzocaine is a(n) _____________. Local anesthetic
Grinding of powder with the help of a liquid is known as ____________. Levigation
What method of comminution is used when working with hard, fracturable powders? Trituration
What is the simplest dosage form? Powder
Finely divided powders intended for application to body cavities are called ___________. Insufflations
How are hygroscopic substance supplied in order to avoid exposure to the air? In granular form and double wrapped.
Substances which absorb moisture from the air are called __________. Hygroscopic
Powders were originally designed as a convenient mode of administering __________. Hard vegetable drugs
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